Professor Claude Wischik

Professor Claude Wischik

Chair in Mental Health (Clin)

Overview

Contact Details

Telephone
work +44 (0)1224 438558
work +44 (0)1224 438559
Email
Address
The University of Aberdeen
TauRx Therapeutics Ltd
1st Floor, Sir Moir Lockhead Building
395 King Street
Aberdeen
AB24 5RP
United Kingdom
Research

Research Interests

Molecular Neuropathology of Alzheimer's Disease, and in particular the therapeutic intervention of tau pathology

Publications

Publications 

Currently viewing:

Page 1 of 7 Results 1 to 10 of 67

  • Hernandes-Alejandro, M, Montaño, S, Harrington, CR, Wischik, CM, Salas-Casas, A, Cortes-Reynosa, P, Pérez Salazar, E, Cazares-Apatiga, J, Apatiga-Perez, R, Ontiveros Torres, MÁ, Perry, G, Pacheco-Herrero, M & Luna-Muñoz, J 2020, 'Analysis of the Relationship Between Metalloprotease-9 and Tau Protein in Alzheimer's Disease', Journal of Alzheimer's Disease, vol. 76, no. 2, pp. 553-569. [Online] DOI: https://doi.org/10.3233/JAD-200146
  • Cranston, AL, Wysocka, A, Steczkowska, M, Zadrozny, M, Palasz, E, Harrington, CR, Theuring, F, Wischik, C, Riedel, G & Niewiadomska, G 2020, 'Cholinergic and inflammatory phenotypes in transgenic tau mouse models of Alzheimer’s Disease and Frontotemporal Lobar Degeneration', Brain Communications, vol. 2, no. 1, fcaa033. [Online] DOI: https://doi.org/10.1093/braincomms/fcaa033
  • Shiells, H, Schelter, BO, Bentham, P, Baddeley, TC, Rubino, CM, Ganesan, H, Hammel, J, Vuksanovic, V, Staff, RT, Murray, AD, Bracoud, L, Wischik, DJ, Riedel, G, Gauthier, S, Jia, J, Moebius, HJ, Hardlund, J, Kipps, CM, Kook, K, Storey, JMD, Harrington, CR & Wischik, CM 2020, 'Concentration-Dependent Activity of Hydromethylthionine on Clinical Decline and Brain Atrophy in a Randomized Controlled Trial in Behavioral Variant Frontotemporal Dementia', Journal of Alzheimer's Disease, vol. 75, no. 2, pp. 501-519. [Online] DOI: https://doi.org/10.3233/JAD-191173
  • Riedel, G, Klein, J, Niewiadomska, G, Kondak, C, Schwab, K, Lauer, D, Magbagbeolu, M, Steczkowska, M, Zadrozny, M, Wydrych, M, Cranston, A, Melis, V, Santos, RX, Theuring, F, Harrington, CR & Wischik, CM 2020, 'Mechanisms of anticholinesterase interference with tau aggregation inhibitor activity in a tau-transgenic mouse model', Current Alzheimer Research, vol. 17, no. 3, pp. 285-296. [Online] DOI: https://doi.org/10.2174/1567205017666200224120926
  • Pollack, SJ, Trigg, J, Khanom, T, Biasetti, L, Marshall, KE, Al-Hilaly, YK, Rickard, JE, Harrington, CR, Wischik, CM & Serpell, LC 2020, 'Paired helical filament forming region of tau (297-391) influences endogenous tau protein and accumulates in acidic compartments in human neuronal cells', Journal of Molecular Biology, vol. 432, no. 17, pp. 4891-4907. [Online] DOI: https://doi.org/10.1016/j.jmb.2020.05.027
  • Al-Hilaly, YK, Foster, BE, Biasetti, L, Lutter, L, Pollack, SJ, Rickard, JE, Storey, JMD, Harrington, CR, Xue, W-F, Wischik, CM & Serpell, LC 2020, 'Tau (297-391) forms filaments that structurally mimic the core of paired helical filaments in Alzheimer's disease brain', FEBS LETTERS, vol. 594, no. 5, pp. 944-950. [Online] DOI: https://doi.org/10.1002/1873-3468.13675
  • Schelter, BO, Shiells, HC, Baddeley, TC, Rubino, CM, Ganesan, H, Hammel, J, Vuksanovic, V, Staff, RT, Murray, AD, Bracoud, L, Riedel, G, Gauthier, S, Jia, J, Bentham, P, Kook, K, Storey, JMD, Harrington, CR & Wischik, CM 2019, 'Concentration-Dependent Activity of Hydromethylthionine on Cognitive Decline and Brain Atrophy in Mild to Moderate Alzheimer’s Disease', Journal of Alzheimer's Disease, vol. 72, no. 3, pp. 931-946. [Online] DOI: https://doi.org/10.3233/JAD-190772
  • Vuksanovic, V, Staff, RT, Ahearn, T, Murray, AD & Wischik, CM 2019, 'Cortical Thickness and Surface Area Networks in Healthy Aging, Alzheimer’s Disease and Behavioral Variant Fronto-Temporal Dementia', International Journal of Neural Systems, vol. 29, no. 6, 1850055. [Online] DOI: https://doi.org/10.1142/S0129065718500557
  • König, M, Berlin, B, Schwab, K, Frahm, S, Theuring, F, Wischik, CM, Harrington, CR, Riedel, G & Klein, J 2019, 'Increased Cholinergic Response in α-Synuclein Transgenic Mice (h-α-synL62)', ACS Chemical Neuroscience, vol. 10, no. 4, pp. 1915-1922. [Online] DOI: https://doi.org/10.1021/acschemneuro.8b00274
  • Flores-Rodríguez, P, Harrington, CR, Wischik, CM, Ibarra-Bracamontes, V, Zarco, N, Navarrete, A, Martínez-Maldonado, A, Guadarrama-Ortíz, P, Villanueva-Fierro, I, Ontiveros-Torres, MA, Perry, G, Alonso, AD, Florán-Garduño, B, Segovia, J & Luna-Muñoz, J 2019, 'Phospho-Tau Protein Expression in the Cell Cycle of SH-SY5Y Neuroblastoma Cells: A Morphological Study', Journal of Alzheimer's Disease, vol. 71, no. 2, pp. 631-645. [Online] DOI: https://doi.org/10.3233/JAD-190155
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