Dr Anke Roelofs

Dr Anke Roelofs
Dr Anke Roelofs
Dr Anke Roelofs

MSc, PhD, FHEA

Senior Lecturer

About
Email Address
a.roelofs@abdn.ac.uk
Office Address

Arthritis and Regenerative Medicine Group
Room 3:16
Institute of Medical Sciences
Foresterhill
Aberdeen AB25 2ZD

School/Department
School of Medicine, Medical Sciences and Nutrition

Biography

I completed my MSc in Medical Biology at the University of Groningen in the Netherlands in 2003 cum laude (first class). I then moved to the University of Oxford where I obtained my DPhil in 2007. I continued my post-doctoral research career at the University of Aberdeen, where I am currently Senior Lecturer in Skeletal Regenerative Medicine. I am a member of the Arthritis and Regenerative Medicine team within the Aberdeen Centre for Arthritis and Musculoskeletal Health (ACAMH).

Qualifications

  • MSc Medical Biology 
    2003 - University of Groningen 
  • DPhil Medical Sciences 
    2007 - University of Oxford 
Research

Current Research

My current research interests are centered around synovial joint biology, with a particular focus on the roles of adult stem cells in joint maintenance, repair, and disease. We seek to enhance our understanding of the identity, ontogeny, regulation and functions of stem cells in the joint using approaches such as genetic cell lineage tracing and scRNA-seq. Our ultimate aim is to develop novel treatments that target endogenous stem cells to promote skeletal joint health and regeneration.

Please visit our Arthritis and Regenerative Medicine page to find out more about our team and the research that we do.

Teaching

Programmes

Publications

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  • Apomine (TM), an inhibitor of HMG-CoA-reductase, promotes apoptosis of myeloma cells in vitro and is associated with a modulation of myeloma in vivo

    Edwards, C. M., Mueller, G., Roelofs, A. J., Chantry, A., Perry, M., Russell, R. G. G., Van Camp, B., Guyon-Gellin, Y., Niesor, E. J., Bentzen, C. L., Vanderkerken, K., Croucher, P. I.
    International Journal of Cancer, vol. 120, no. 8, pp. 1657-1663
    Contributions to Journals: Articles
  • Selective inhibition of Rab prenylation by a phosphonocarboxylate analogue of risedronate induces apoptosis, but not S-phase arrest, in human myeloma cells

    Roelofs, A. J., Hulley, P. A., Meijer, A., Ebetino, F. H., Russell, R. G. G., Shipman, C. M.
    International Journal of Cancer, vol. 119, no. 6, pp. 1254-1261
    Contributions to Journals: Articles
  • Molecular mechanisms of action of bisphosphonates: current status

    Roelofs, A. J., Thompson, K., Gordon, S. A., Rogers, M. J.
    Clinical Cancer Research, vol. 12, no. 20 PT 2, pp. 6222S-6230S
    Contributions to Journals: Review articles
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