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The Institute of Medical Sciences

Dr Anke Roelofs

Dr Anke Roelofs
Dr Anke Roelofs
Dr Anke Roelofs

MSc, PhD, FHEA

Senior Lecturer

About
Email Address
a.roelofs@abdn.ac.uk
Office Address

Arthritis and Regenerative Medicine Group
Room 3:16
Institute of Medical Sciences
Foresterhill
Aberdeen AB25 2ZD

School/Department
School of Medicine, Medical Sciences and Nutrition

Biography

I completed my MSc in Medical Biology at the University of Groningen in the Netherlands in 2003 cum laude (first class). I then moved to the University of Oxford where I obtained my DPhil in 2007. I continued my post-doctoral research career at the University of Aberdeen, where I am currently Senior Lecturer in Skeletal Regenerative Medicine. I am a member of the Arthritis and Regenerative Medicine team within the Aberdeen Centre for Arthritis and Musculoskeletal Health (ACAMH).

Qualifications

  • MSc Medical Biology 
    2003 - University of Groningen 
  • DPhil Medical Sciences 
    2007 - University of Oxford 
Research

Current Research

My current research interests are centered around synovial joint biology, with a particular focus on the roles of adult stem cells in joint maintenance, repair, and disease. We seek to enhance our understanding of the identity, ontogeny, regulation and functions of stem cells in the joint using approaches such as genetic cell lineage tracing and scRNA-seq. Our ultimate aim is to develop novel treatments that target endogenous stem cells to promote skeletal joint health and regeneration.

Please visit our Arthritis and Regenerative Medicine page to find out more about our team and the research that we do.

Teaching

Programmes

Courses

Publications

Page 3 of 5 Results 21 to 30 of 43

  • In vivo phenotypic characterisation of nucleoside label-retaining cells in mouse periosteum

    Cherry, H. M., Roelofs, A. J., Kurth, T., De Bari, C.
    European Cells & Materials, vol. 27, pp. 185-195
    Contributions to Journals: Articles

  • Cell-based Approaches to Joint Surface Repair: A Research Perspective

    Roelofs, A. J., Rocke, J. P. J., De Bari, C.
    Osteoarthritis and Cartilage, vol. 21, no. 7, pp. 892-900
    Contributions to Journals: Review articles

  • Bisphosphonates: Mechanisms of action

    Roelofs, A. J., Shay, G., Rogers, M.
    Handbook of cancer-related bone disease. Coleman, R., Abrahamsson, P., Hadji, P. (eds.). 2 edition. BioScientifica, pp. 75-99, 25 pages
    Chapters in Books, Reports and Conference Proceedings: Chapters

  • Influence of bone affinity on the skeletal distribution of fluorescently labeled bisphosphonates in vivo

    Roelofs, A. J., Stewart, C. A., Sun, S., Blazewska, K. M., Kashemirov, B. A., McKenna, C. E., Russell, R. G. G., Rogers, M. J., Lundy, M. W., Ebetino, F. H., Coxon, F.
    Journal of Bone and Mineral Research, vol. 27, no. 4, pp. 835-847
    Contributions to Journals: Articles

  • Synergistic inhibitory effect of apomine and lovastatin on osteosarcoma cell growth

    Moriceau, G., Roelofs, A. J., Brion, R., Redini, F., Ebetino, F. H., Rogers, M. J., Heymann, D.
    Cancer, vol. 118, no. 3, pp. 750-760
    Contributions to Journals: Articles

  • Directed migration of human bone marrow mesenchymal stem cells in a physiological direct current electric field

    Zhao, Z., Watt, C., Karystinou, A., Roelofs, A. J., McCaig, C. D., Gibson, I. R., De Bari, C.
    European Cells & Materials, vol. 22, no. -, pp. 344-358
    Contributions to Journals: Articles

  • Synthesis and characterization of novel fluorescent nitrogen-containing bisphosphonate imaging probes for bone active drugs

    Sun, S., Blazewska, K. M., Kashemirov, B. A., Roelofs, A. J., Coxon, F. P., Rogers, M. J., Ebetino, F. H., Mckenna, M. J., Mckenna, C. E.
    Phosphorus, Sulfur and SIlicon and the Related Elements, vol. 186, no. 4, pp. 970-971
    Contributions to Journals: Articles

  • Bisphosphonates: molecular mechanisms of action and effects on bone cells, monocytes and macrophages

    Roelofs, A. J., Thompson, K., Ebetino, F., Rogers, M. J., Coxon, F.
    Current Pharmaceutical Design, vol. 16, no. 27, pp. 2950-2960
    Contributions to Journals: Review articles

  • A role for L-α-lysophosphatidylinositol and GPR55 in the modulation of migration, orientation and polarization of human breast cancer cells

    Ford, L. A., Roelofs, A. J., Anavi-Goffer, S., Mowat, L., Simpson, D. G., Irving, A. J., Rogers, M. J., Rajnicek, A. M., Ross, R. A.
    British Journal of Pharmacology, vol. 160, no. 3, pp. 762-771
    Contributions to Journals: Articles

  • Bisphosphonates: mechanisms of action

    Roelofs, A. J., Rogers, M.
    Handbook of Cancer-Related Bone Disease. Coleman, R. E., Abrahamsson, P. A., Hadji, P. (eds.). BioScientifica, pp. 71-89, 19 pages
    Chapters in Books, Reports and Conference Proceedings: Chapters
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