Anaesthesia & Intensive CareThe anaesthesia and intensive care group’s main research interest is mitochondrial damage and oxidative stress and its impact on inflammation as related to anaesthesia, pain and critical illness. Sepsis is the major cause of death on the intensive care unit usually as a result of multiple organ failure, when the mortality rate is in excess of 70%. We are investigating the role of mitochondrial damage and oxidative stress in driving the dysregulated inflammatory responses which occur during sepsis and assessing possible novel therapeutic approaches. We also have ongoing research related to the role of oxidative stress in the mechanisms of pain resulting from chemotherapy 

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