- Neuronal Disease
Every behaviour, action or decision we take in the world is governed by our nervous system and diseases of the nervous system break down our ability to function. Sadly such disorders are all too common; damage to the spinal cord will paralyze limbs, motor neuron disease or Parkinson’s disease disable movement while diabetic neuropathy will lead to loss of peripheral nerves with many damaging consequences. More pernicious are the diseases that effect thought and cognition, destroying the ability to reason. Alzheimers disease will spiral into complete dementia, depression will degrade the pleasure of life, schizophrenia fracture coherent thought.
Researchers in Aberdeen neuroscience are tackling all these diseases through the discovery of the genes and proteins that underlie these disorders and understanding how malfunctions in these molecules can lead to disease. Many researchers are taking a translational or “bench to bedside” approach, working with clinicians to take molecular discoveries towards the development of cure for disease.
- The Aging Brain
A SPECT scan of blood flow (A) and positron emission tomorgraphy (B) in Alzheimer’s disease and a T2 axial MRI scan of a normal brain (C) (Murray)
A successful line of research by Aberdeen scientists has been the study of the aging brain; not a disease but a process of inevitable deterioration that we all must bear. A combination of brain imaging, genetic, molecular and pathological studies aim to provide a complete neurobiological description of the events that lead to the progressive failure of the brain with age. These studies will show how this decline may be slowed.
The Aging Brain