Dr Mairi McLean

Dr Mairi McLean
BSc(Hons), MBChB (Hons), MRCP, PhD

Senior Clinical Lecturer

Overview

Contact Details

Telephone
work +44 (0)1224 437319
Email
Address
The University of Aberdeen School of Medicine, Medical Sciences & Nutrition
University of Aberdeen
Rm 3.26, Institute of Medical Sciences
Foresterhill
Aberdeen
AB25 2ZD
 

Biography

Senior Clinical Lecturer and Honorary Consultant in Gastroenterology, University of Aberdeen, UK (2011-date)

Visiting Research Fellow, National Cancer Institute, NIH, USA (2012–2015). Funded by Crohn’s & Colitis Foundation of America. Department of Molecular Immunoregulation, Cancer & Inflammation Program, National Cancer Institute, NIH, USA.


Education editor for Gut (2012-date), an international journal of gastroenterology & hepatology. Monthly podcast interview and editing ‘journal scan: GI highlights from the literature’.


Secretary of the Aberdeen Immunology group, a regional group of the British Society of Immunology (2016-date).


Member of the Scientific Advisory Group, Grampian Tissue Biorepository, Dept of Pathology, NHS Grampian, UK

 

 

Research

Research Interests

Mucosal immunology and epithelial barrier dysfunction in inflammatory bowel disease

Anti-inflammatory cytokine networks as treatment strategy for inflammatory bowel disease

The role of chronic inflammation in the pathogenesis of sporadic colorectal cancer

Novel biomarkers to aid diagnosis, assessment of disease severity and response to treatment in inflammatory bowel disease and gastrointestinal cancers

Current Research

The role of HMGB1 in the pathogenesis of oesophageal neoplastic progression - Ross Porter - B Med Sci student (intercalating Medical student) 2016-2017 (funded by Pathology Society Bursary)

The role of HMGB1 in colorectal cancer 2015-2018 (funded by NHS Grampian Endowments and Friends of Anchor) - Sandra Hapca - Medical Reseach Scotland Studentship 2017

Defining the role of interleukin-27 in human inflammatory bowel disease - a novel therapy? - Daniel Brice BSc Hons - PhD student 2016-2019 (funded by PhD studentship from CICRA and NHS Endowments)

Interleukin-33 is a novel treatment target in inflammatory bowel disease - 2017-2019  (funded by Mason Medical Research Trust)

 

Collaborations

Dr Scott Durum, Immunologist, National Cancer Institute, National Institutes of Health, Maryland, USA

Professor Graeme Murray, Professor of Pathology, University of Aberdeen, UK

Professor Emad El-Omar, Professor of Gastroenterology, University of New South Wales, Sydney, Australia

Dr Georgina Hold, Senior lecturer in Gastroenterology, University of Aberdeen, UK

Dr Heather Wilson, Senior Lecturer in Immunology, University of Aberdeen, UK

Dr Alasdair MacKenzie, Reader Molecular Biology, University of Aberdeen, UK

Further Info

External Responsibilities

Clinical consultant gastroenterologist, NHS Grampian

Publications

Publications 

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