Professor Dana Dawson

Professor Dana Dawson
Professor Dana Dawson
Professor Dana Dawson

DM, FRCP, D.Phil, FESC

Chair in Cardiovascular Medicine

About

Biography

Professor Dawson qualified in medicine at University of Medicine “Grigore T. Popa”, Iasi, Romania. After completing her MRCP with the Royal College of Physicians in London and read for a D. Phil in Cardiovascular Medicine at Merton College, University of Oxford, she trained in Cardiovascular Medicine in Edinburgh, Oxford and London in the UK and at the University of Virginia, Charlottesville, in the USA.  In 2010 she moved to the University of Aberdeen and Aberdeen Royal Infirmary where she currently is Professor of Cardiovascular Medicine and Consultant Cardiologist.

She made a significant contribution in advancing knowledge in acute stress induced (Takotsubo) cardiomyopathy,  having delivered several landmark mechanistic clinical trials. Takotsubo studies are ongoing in Aberdeen who lead the Scottish Takotsubo Registry which has been accruing all cases since 2010.

There is keen interest in other topics such as exercise based interventions and pharmacological therapies to improve cardio-metabolic health in patients with type 2 diabetes, mechanistic trials unmasking heart failure in patients with COPD,  deep cardiac phenotyping and strategies for prevention of cardio-toxicity in cardio-oncology. A cardio-dentistry collaboration explores the causal role of pathobionts in acute myocardial infarction.

Together with cardiac MR physicists, the group have developed the world's first cardiac array coil for cardiac Field Cycling Magnetic Resonance to investigate the unique characteristics of the heart muscle visible at low field and field cycling domains. 

Professor Dana Dawson leads the Cardiology and Cardiovascular Research Unit who have strong collaborative links with many other UK centres, participating in multi-centre clinical research studies.

Memberships and Affiliations

Internal Memberships

Team members and close collaborators:

Dr. David Gamble - BHF Clinical Research Fellow, Clinical Lecturer

Dr. Hilal Khan - Clinical Research Fellow

Dr. Susanth Alapati - BHF Clinical (Dental) Research Fellow

Dr Sara Sharif - Elphinstone Clinical (Dental) Research Fellow

Ms Amelia Rudd, MSc - BHF AHP Clinical Research Fellow

Miss Lesley Cheyne - Cardiovascular Technician

Ms Janaki Srivanasan – Senior Research Sonographer

Dr. Lionel Broche – Lecturer in Fast Field Cycling MR Physics

Dr. Gareth Davies - Fast Field Cycling MR Physics Research Fellow

Dr. James Ross - Lecturer in Cardiovascular Magnetic Resonance Physics

Dr. Caroline Scally – former BHF Clinical Research Fellow

Miss Nadine Godsman – former BHF non-clinical PhD student

Dr. Alice Mezincescu – Clinical Lecturer (former BHF Clinical Research Fellow)

Dr. Chaitanya Pradeep Joshi - former Clinical Research Fellow - Dental, Elphinstone Scholar

Dr. Hassan Abbas – BHF Clinical Research Fellow

 

Research Nurses:

RN Valerie Harries

RN Jocelyn Abernethy

RN Debbie Olaotan

RN Pauline Crozier

 

Research Radiographers:

Mr Mike Hendry (MRI)

Ms Nicola Crouch (MRI)

Ms Laura Reid (MRI)

Ms Michelle Mauchline (MRI)

Mrs Denise Forrest (CT)

Ms Louise Lamley (CT)

 

External Memberships

She is a member of the British Cardiovascular Society, American Heart Association, Fellow of the European Society of Cardiology, Chair of the Myocardial Function Working Group of the European Society of Cardiology and head of the Taskforce on Takotsubo within the Heart Failure Association of the European Society of Cardiology.

Prizes and Awards

Most recent mentored scientific investigations shortlisted for prize awards include:

1.    Janaki Srivanasan – winner of the British Society of Echocardiography Young Investigator Research Prize, October 2016

2.    Caroline Scally – finalist at the Early Career award, Society of Cardiovascular Magnetic Resonance, Washington, January 2017

3.    Caroline Scally – finalist at the Samuel A Levine Young Investigator Award of the American Heart Association, Anaheim, CA, November 2017

4.    Nadine Godsman – winner of the Young Investigator’s prize of the British Pharmacological Society – Pharmacology, December 2017 – London, England

5.    Caroline Scally - finalist at the Melvin Judkins Young Investigator Award of the American Heart Association, Chicago, IL, November 2018

6.    Alice Mezincescu – finalist at the Early Career Award-Translational Sciences of the Society of Cardiovascular Magnetic Resonance, Seattle, February 2019

7.   Chaitanya Joshi – Coronary Artery Disease Risk is Increased by Periodontitis Pathobionts, winner of the Sir Wilfred Fish Prize of The British Society of Periodontology and Implant Dentistry, London, November 2021

8.    Alice Mezincescu – Insulin Resistance in Type 2 Diabetes is Moderated by Saturated Fatty Acids Abundance and Turnover, finalist at the Early career award on Lifestyle and Cardiometabolic Risk, American Heart Association scientific sessions, Chicago, November 2022

9.   Amelia Rudd - Cardiovascular and Non-Cardiovascular Prescribing and Mortality after Takotsubo - winner of the Scottish Cardiac Society Award, October 2023

Research

Funding and Grants

RESEARCH GRANTS  – current:

1. Sodium-glucose transporter type 2 inhibition in anthracycline-related cardiotoxicity, D Dawson, D E Newby, BHF CRTF FS/CRTF/23/24508, 2024-2027, £363,697

2. Bioinformatics analysis of single cell SEQUENCing of Human PBMC in acutE cardiac disease- SEQUENCE study, H Khan, E Collie-Duguid, D Dawson, Tenovus Scotland, 03, 2023, £14,557

3. Importance of Gender Differences in secondary prevention and longterm outcomes of cardiovascular disease, T Pana (PI), D Dawson, P Myint, NHS Grampian Endowments, 2022-2023, £16,055

4. Replacement of (ultrasound) echocardiography equipment for clinical research, BHF Infrastructure Grant IG/F/21/50010, D Dawson, 2022, £73,604

5. Epigenetic Phase Variation of Periodontal Bacteria – a Mechanistic Contributor to Coronary Artery Disease, BHF Project Grant PG/22/11117, K Hijazi (PI) and D Dawson, £217,509, 2022-2025

6. Life-style interventions for modulation the Brain PhEnotype of TAKOtsUbo Cardiomyopathy BREAKOUT), D Dawson (PI), NHS Grampian Endowments, £310,552, 2020-2024

7. Epidemiology and predisposition of acute stress-induced (takotsubo) Cardiomyopathy - BHF Research Training Fellowship (FS/RTF/20/30009, for Ms Amelia Rudd): D Dawson (CI), David Newby, 2021-2023, £215,051

8. Demographic, multi-morbidity and genetic impact on myocardial involvement and its recovery from Covid-19: The Covid-Heart Study, NIHR, CI John Greenwood, D Dawson co-applicant, £775,095

9. The next leap in cardiac magnetic resonance imaging: cycling the field: D Dawson (CI), D Lurie, L Broche, J Ross, H Abbas: BHF New Horizons Grant no. NH/19/1/34595, 2020-2024, £277,722

10. Towards Elucidating the Genetic Predisposition for Acute Stress-Induced (Takostubo) Cardiomyopathy: D Dawson (Chief Investigator), Z Miedzybrodzka, Chest Heart and Stroke Scotland, 2019-2023, £24,950

11. PhysicaL Exercise and mental wellbeing rehabilitation for Acute StrEss-induced takotsubo cardiomyopathy: The PLEASE trial, BHF Project Grant no. PG/18/35/33786; D Dawson (Chief Investigator), D.E. Newby, Marc Petrie, S Leslie, C.C. Lang, G Horgan, S Gray, C Williams, 2019-2023, £298,134

12. Cardiac Energetics and Breast Cancer Treatment, Tenovus Scotland 01, D Dawson (Chief Investigator), R Sharma, 2019-2023, £19,595

13. Resting Cardiac Energetics in Patients Undergoing Anthracycline Chemotherapy for Breast Cancer, Friends of Anchor, D Dawson (Chief Investigator), R Sharma, 2019-2023, £14,724

Publications

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  • Intravenous sodium nitrite in acute ST-elevation myocardial infarction: a randomized controlled trial (NIAMI)

    Siddiqi, N., Neil, C., Bruce, M., Maclennan, G., Cotton, S. C., Papadopoulou, S., Feelisch, M., Bunce, N., Lim, P. O., Hildick-Smith, D., Horowitz, J., Madhani, M., Boon, N., Dawson, D., Kaski, J. C., Frenneaux, M., NIAMI investigators
    European Heart Journal, vol. 35, no. 19, pp. 1255-1262
    Contributions to Journals: Articles
  • MOLLI T1 mapping versus T2 W-SPAIR at 3T: myocardial area at risk measurements and the influence of microvascular obstruction

    Cameron, D., Siddiqi, N., Neil, C. J., Jagpal, B., Bruce, M., Richardson, A., Redpath, T. W., Frenneaux, M. P., Dawson, D. K.
    Journal of Cardiovascular Magnetic Resonance, vol. 16, O22
    Contributions to Journals: Articles
  • Nitrites in Acute Myocardial Infarction

    Siddiqi, N., Bruce, M., Neil, C. J., MacLennan, G., Cotton, S., Papadopoulou, S. A., Jagpal, B., Brown, S., Gonzalez, F. P., Singh, S., Schwarz, K., Feelisch, M., Bunce, N., Lim, P. O., Hildick-Smith, D., Horowitz, J., Madhani, M., Boon, N., Dawson, D., Kaski, J., Frenneaux, M. P.
    Circulation, vol. 128, no. 24, pp. 2705
    Contributions to Journals: Abstracts
  • Prognostic value of cardiovascular magnetic resonance in patients with suspected arrhythmogenic right ventricular cardiomyopathy

    Deac, M., Alpendurada, F., Fanaie, F., Vimal, R., Carpenter, J., Dawson, A., Miller, C., Roussin, I., di Pietro, E., Ismail, T. F., Roughton, M., Wong, J., Dawson, D., Till, J. A., Sheppard, M. N., Mohiaddin, R. H., Kilner, P. J., Pennell, D. J., Prasad, S. K.
    International Journal of Cardiology, vol. 168, no. 4, pp. 3514-3521
    Contributions to Journals: Articles
  • Cardiac metabolism in hypertrophy and heart failure: implications for therapy

    Siddiqi, N., Singh, S., Beadle, R., Dawson, D., Frenneaux, M.
    Heart Failure Reviews, vol. 18, no. 5, pp. 595-606
    Contributions to Journals: Articles
  • Right ventricular function in left ventricular disease: pathophysiology and implications

    Schwarz, K., Singh, S., Dawson, D., Frenneaux, M.
    Heart, Lung and Circulation, vol. 22, no. 7, pp. 507-511
    Contributions to Journals: Articles
  • Cardiac sarcoid or arrhythmogenic right ventricular cardiomyopathy: a role for Positron Emission Tomography (PET)?

    Choo, W. K., Denison, A. R., Miller, D. R., Dempsey, O. J., Dawson, D. K., Broadhurst, P. A.
    Journal of Nuclear Cardiology, vol. 20, no. 3, pp. 479-480
    Contributions to Journals: Articles
  • Protocol: does sodium nitrite administration reduce ischaemia-reperfusion injury in patients presenting with acute ST segment elevation myocardial infarction? Nitrites in acute myocardial infarction (NIAMI)

    Siddiqi, N., Bruce, M., Neil, C. J., Jagpal, B., MacLennan, G. S., Cotton, S. C., Papadopoulo, S. A., Bunce, N., Lim, P., Schwarz, K., Singh, S., Hildick-Smith, D., Horowitz, J. D., Madhani, M., Boon, N., Kaski, J., Dawson, D., Frenneaux, M. P.
    Journal of translational medicine, vol. 11, 116
    Contributions to Journals: Articles
  • Living Without Creatine: Unchanged Exercise Capacity and Response to Chronic Myocardial Infarction in Creatine-Deficient Mice

    Lygate, C. A., Aksentijevic, D., Dawson, D., Ten Hove, M., Phillips, D., de Bono, J. P., Medway, D. J., Sebag-Montefiore, L. M., Hunyor, I., Channon, K., Clarke, K., Zervou, S., Watkins, H., Balaban, R., Neubauer, S.
    Circulation Research, vol. 112, no. 6, pp. 945-955
    Contributions to Journals: Articles
  • Prognostic Role of CMR in Patients Presenting With Ventricular Arrhythmias

    Dawson, D. K., Hawlisch, K., Prescott, G., Roussin, I., Di Pietro, E., Deac, M., Wong, J., Frenneaux, M. P., Pennell, D. J., Prasad, S. K., Prescott, G. J.
    JACC. Cardiovascular Imaging, vol. 6, no. 3, pp. 335-344
    Contributions to Journals: Articles
  • GPIb VNTR C/C genotype may predict embolic events in infective endocarditis

    Daga, S., Shepherd, J. G., Hung, R. K. Y., Callaghan, J. G. S., Dawson, D. K., Padfield, G. J., Fitzgerald, J. R., Newby, D. E.
    The Journal of heart valve disease, vol. 22, no. 1, pp. 133-141
    Contributions to Journals: Articles
  • Metabolic therapy for heart failure including diastolic heart failure

    Siddiqi, N., Dawson, D., Rudd, A., Frenneaux, M.
    Heart and Metabolism, no. 57, pp. 18-24
    Contributions to Journals: Articles
  • Slowly resolving global myocardial inflammation/oedema in Tako-Tsubo cardiomyopathy: evidence from T2-weighted cardiac MRI

    Neil, C., Nguyen, T. H., Kucia, A., Crouch, B., Sverdlov, A., Chirkov, Y., Mahadavan, G., Selvanayagam, J., Dawson, D., Beltrame, J., Zeitz, C., Unger, S., Redpath, T., Frenneaux, M., Horowitz, J.
    Heart, vol. 98, no. 17, pp. 1278-1284
    Contributions to Journals: Articles
  • Contemporary imaging of the pericardium

    Dawson, D., Rubens, M., Mohiaddin, R.
    JACC. Cardiovascular Imaging, vol. 4, no. 6, pp. 680-684
    Contributions to Journals: Articles
  • Platelet receptor polymorphisms do not influence Staphylococcus aureus-platelet interactions or infective endocarditis

    Daga, S., Shepherd, J. G., Callaghan, J. G. S., Hung, R. K. Y., Dawson, D. K., Padfield, G. J., Hey, S. Y., Cartwright, R. A., Newby, D. E., Fitzgerald, J. R.
    Microbes and Infection, vol. 13, no. 3, pp. 216-225
    Contributions to Journals: Articles
  • Regional thicknesses and thickening of compacted and trabeculated myocardial layers of the normal left ventricle studied by cardiovascular magnetic resonance

    Dawson, D. K., Maceira, A. M., Raj, V. J., Graham, C., Pennell, D. J., Kilner, P. J.
    Circulation. Cardiovascular imaging, vol. 4, no. 2, pp. 139-146
    Contributions to Journals: Articles
  • A saw-tooth rather than noncompacted variant of left ventricular structure

    Dawson, D. K., Davlouros, P. A., Kilner, P. J.
    Journal of the American College of Cardiology, vol. 57, no. 8, pp. 999
    Contributions to Journals: Letters
  • Assessment of pericardial diseases and cardiac masses with cardiovascular magnetic resonance

    Dawson, D., Mohiaddin, R.
    Progress in Cardiovascular Diseases, vol. 54, no. 3, pp. 305-319
    Contributions to Journals: Articles
  • Paradoxical embolism via an atrial septal defect: in flagrante delicto

    Reid, L. E. M., Dawson, D. K.
    Journal of the American College of Cardiology, vol. 56, no. 22, pp. e43
    Contributions to Journals: Articles
  • Prognostic significance of myocardial fibrosis in hypertrophic cardiomyopathy

    O'Hanlon, R., Grasso, A., Roughton, M., Moon, J. C., Clark, S., Wage, R., Webb, J., Kulkarni, M., Dawson, D., Sulaibeekh, L., Chandrasekaran, B., Bucciarelli-Ducci, C., Pasquale, F., Cowie, M. R., McKenna, W. J., Sheppard, M. N., Elliott, P. M., Pennell, D. J., Prasad, S. K.
    Journal of the American College of Cardiology, vol. 56, no. 11, pp. 867-874
    Contributions to Journals: Articles
  • Significant aortic coarctation presenting as subarachnoid hemorrhage in the adult

    Martin, R., Sellar, R., Dawson, D.
    Journal of the American College of Cardiology, vol. 55, no. 14, pp. e25
    Contributions to Journals: Articles
  • Quantitative myocardial contrast echocardiography during pharmacological stress for diagnosis of coronary artery disease: a systematic review and meta-analysis of diagnostic accuracy studies

    Abdelmoneim, S. S., Dhoble, A., Bernier, M., Erwin, P. J., Korosoglou, G., Senior, R., Moir, S., Kowatsch, I., Xian-Hong, S., Muro, T., Dawson, D., Vogel, R., Wei, K., West, C. P., Montori, V. M., Pellikka, P. A., Abdel-Kader, S. S., Mulvagh, S. L.
    European Journal of Echocardiography, vol. 10, no. 7, pp. 813-825
    Contributions to Journals: Articles
  • Prognostic value of dipyridamole stress myocardial contrast echocardiography: comparison with single photon emission computed tomography

    Dawson, D., Kaul, S., Peters, D., Rinkevich, D., Schnell, G., Belcik, J. T., Wei, K.
    Journal of the American Society of Echocardiography, vol. 22, no. 8, pp. 954-960
    Contributions to Journals: Articles
  • Inter-valvular fibrosa pseudo-aneurysm as a late complication after aortic valve surgery

    Dawson, D., Pessotto, R., Neary, P.
    European Journal of Echocardiography, vol. 10, no. 1, pp. 169-170
    Contributions to Journals: Articles
  • Cardiac phenotype of mitochondrial creatine kinase knockout mice is modified on a pure C57BL/6 genetic background

    Lygate, C. A., Hunyor, I., Medway, D., de Bono, J. P., Dawson, D., Wallis, J., Sebag-Montefiore, L., Neubauer, S.
    Journal of Molecular and Cellular Cardiology, vol. 46, no. 1, pp. 93-99
    Contributions to Journals: Articles
  • Management of the ascending aortic pseudo-aneurysms: a single centre experience

    Dawson, D., Clarke, N. R. A., Banning, A. P.
    International Journal of Cardiology, vol. 130, no. 1, pp. 92-95
    Contributions to Journals: Articles
  • An unusual cause of severe mitral regurgitation: aberrantly inserted chordae tendineae

    Dawson, D., Mankad, P., Bloomfield, P., Boon, N. A.
    Journal of the American Society of Echocardiography, vol. 21, no. 1, pp. 90.e3-90.e4
    Contributions to Journals: Articles
  • Transthoracic diagnosis of left atrial appendage myxoma by real-time 3-dimensional echocardiography

    Dawson, D., Jin, X. Y., Mitchell, A. R. J., Ormerod, O. O., Becher, H.
    Journal of the American Society of Echocardiography, vol. 18, no. 2, pp. 192-193
    Contributions to Journals: Articles
  • Can contrast dobutamine stress echocardiography be performed with standardized imaging settings for everybody?

    Thibault, H., Timperley, J., Ehlgen, A., Pariente, A., Dawson, D., Becher, H.
    Journal of the American Society of Echocardiography, vol. 18, no. 11, pp. 1194-1202
    Contributions to Journals: Articles
  • Supranormal myocardial creatine and phosphocreatine concentrations lead to cardiac hypertrophy and heart failure: insights from creatine transporter-overexpressing transgenic mice

    Wallis, J., Lygate, C. A., ten Hove, M., Fischer, A., Schneider, J. E., Sebag-Montefiore, L., Dawson, D., Hulbert, K., Zhang, W., Zhang, M. H., Watkins, H., Clarke, K., Neubauer, S.
    Circulation, vol. 112, no. 20, pp. 3131-3139
    Contributions to Journals: Articles
  • nNOS gene deletion exacerbates pathological left ventricular remodeling and functional deterioration after myocardial infarction

    Dawson, D., Lygate, C. A., Zhang, M. H., Hulbert, K., Neubauer, S., Casadei, B.
    Circulation, vol. 112, no. 24, pp. 3729-3737
    Contributions to Journals: Articles
  • Atrio-ventricular block and ventricular tacchycardia induced by severe coronary spasm

    Dawson, D., Wistow, T. E.
    International Journal of Cardiology, vol. 97, no. 2, pp. 319-319
    Contributions to Journals: Letters
  • Quantitative 3-dimensional echocardiography for accurate and rapid cardiac phenotype characterization in mice

    Dawson, D., Lygate, C. A., Saunders, J., Schneider, J. E., Ye, X., Hulbert, K., Noble, J. A., Neubauer, S.
    Circulation, vol. 110, no. 12, pp. 1632-1637
    Contributions to Journals: Articles
  • Measurement of myocardial blood flow velocity reserve with myocardial contrast echocardiography in patients with suspected coronary artery disease: comparison with quantitative gated Technetium 99m sestamibi single photon emission computed tomography

    Dawson, D., Rinkevich, D., Belcik, T., Jayaweera, A. R., Rafter, P., Kaul, S., Wei, K.
    Journal of the American Society of Echocardiography, vol. 16, no. 11, pp. 1171-1177
    Contributions to Journals: Articles
  • Case study: metformin-associated lactic acidosis: could orlistat be relevant?

    Dawson, D., Conlon, C.
    Diabetes Care, vol. 26, no. 8, pp. 2471-2472
    Contributions to Journals: Articles
  • Automated, nonrigid alignment of clinical myocardial contrast echocardiography image sequences: comparison with manual alignment

    Noble, J. A., Dawson, D., Lindner, J., Sklenar, J., Kaul, S.
    Ultrasound in Medicine & Biology, vol. 28, no. 1, pp. 115-123
    Contributions to Journals: Articles
  • Skeletal muscle microvascular recruitment by physiological hyperinsulinemia precedes increases in total blood flow

    Vincent, M. A., Dawson, D., Clark, A. D. H., Lindner, J. R., Rattigan, S., Clark, M. G., Barrett, E. J.
    Diabetes, vol. 51, no. 1, pp. 42-8
    Contributions to Journals: Articles
  • Vascular recruitment in skeletal muscle during exercise and hyperinsulinemia assessed by contrast ultrasound

    Dawson, D., Vincent, M. A., Barrett, E. J., Kaul, S., Clark, A., Leong-Poi, H., Lindner, J. R.
    American Journal of Physiology: Endocrinology and Metabolism, vol. 282, no. 3, pp. E714-20
    Contributions to Journals: Articles
  • Non-invasive assessment of myocardial blood flow using echocardiography

    Dawson, D., Firoozan, S.
    International Journal of Cardiology, vol. 73, no. 2, pp. 105-13
    Contributions to Journals: Articles
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