Outputs

Outputs
Grants awarded in 2013
  1. £59, 965.  Chest Heart and Stroke Scotland.  Childhood asthma prevalence in 2014- how and why has this changed over the past 50 years?  Lead Applicant.  Jan-Dec 2014.
  2. £22,000. Health Informatics Research. Fetal origins of autistic spectrum disorder.  Co-Applicant.  Jan-Dec 2014.
  3. £12,000.  Health Informatics Research. PhD studentship.  Lead Applicant.  March 2014-Feb 2017.
  4. £9,500.  Tenovus Scotland. A Study of Children’s Bronchial Airway Epithelial Cell Response to Common Environmental Exposures.  Lead Applicant.  March 2014-Feb 2015.
  5. £9, 935. Tenovus Scotland. Using nasal airway cells to study wheezing conditions in children.  Co-Applicant. Jan-Dec 2014.
  6. £199,000. Action Medical Research. Does the prescribing of asthma controller medication according to beta 2 receptor gene status improve quality of life in 12-21 year olds with asthma? Co Applicant. Jan 2014- Dec 2015.
  7. £41,405, Chief Scientists Office of the Scottish Executive.  Volatile organic compounds and risk of asthma and allergy: a systematic review and meta-analysis of observational and interventional studies. CZG/2/573. Jan 2013-August 2013.
  8. £2,579,402 NIHR Health Technology Assessment  Programme:  A randomised, double-blind placebo controlled trial of the effectiveness of low dose oral theophylline as an adjunct to inhaled corticosteroids in preventing exacerbations of chronic obstructive pulmonary disease. 11/58/15. Sept 2013-Aug 2017
  9. £89,942. Chest Heart and Stroke Scotland. Is childhood wheezy bronchitis an early determinant of chronic obstructive pulmonary disease? A longitudinal study. March 2013-Febr 2016
  10. £109,000. NHS Grampian and Scottish Government.  Use of indoor air quality measurements as an avenue and adjunct to motivational interview in smoking cessation. Jan 2013- May 2014.
  11. £1,999,932 Asthma UK Centre for Applied Research. AC-2012-01. Through University of Edinburgh.  Oct 2013-Sept 2018.
  12. £174,237. The effect of nanoparticles on in-vitro airway epithelial cell function in children and adults with and without asthma. ETM/274. Sept 2013-Aug 2015.
  13. £286,672 NIHR Health Technology Assessment Programme. The Clinical and Cost-effectiveness of Temporarily Quadrupling the Dose of Inhaled Steroid to Prevent Asthma Exacerbations: a Pragmatic, Randomised, Normal Care, Controlled Trial. May 2013- October 2017.
  14. £103,652: Health Sciences Scotland, Cystic Fibrosis Trust. A first time in man phase I/IIa study for Lynovex® in cystic fibrosis. Jan 2014-Jan 2015.
  15. £190,761. CSO.  First Steps to Smoke-free: Using air-quality feedback to facilitate smoke-free homes through the NHS Lanarkshire First Steps Programme (CZH/4/983).
Other Active Grants
  1. £135,000 Saudi Ministry of Higher Education. Study of asthma to investigate in utero effects of diet. (SAUDI). February 2010-July 2014.
  2. £174,237Chief Scientists Office of the Scottish Executive. Antenatal influences on, and inter-relationships between, airway epithelial cell responses and lung function in neonates. CAF/10/06 August 2010 – July 2013
  3. £2.1 million; Natural Environment Research Council/Medical Research Council: From Airborne exposures to BiologicaL Effects (FABLE): the impact of nano-particles on health. GMW PI and sole applicant (Collaborative project with University of Birmingham; £250,000 to UoA). May 2011-October 2014
  4. £90,000; Royal Embassy of Saudi Arabia: The role of airway epithelial cell toll-like receptors in asthmatic and healthy subjects. PhD studentship. Oct 2011-Oct 2014
  5. Government of Kuwait: £90,000; Relationship between eosinophils and T cell Subsets in asthma.  PhD studentship Oct 2010-Oct 2014
  6. Axiken Pharmaceuticals, San Diego, U.S.A.: £40,000;  CCR3 antagonism of inflammatory cell function.  Jan-2010-Dec 2014
  7. £75,000 ARCHIE charity. Airway epithelial cell phenotype in asthma and wheezing conditions. October 2010- September 2014.
  8. £125,000 Glaxo Smith Kline. Investigator-initiated Study. Prescribing and dispensing practice for Asthma medication in Scotland. March 2011- January 2014
  9. £72,487, Development and clinical piloting of a dietary soup intervention during pregnancy with the aim of reducing the likelihood of childhood asthma. Knowledge Exchange Transfer Fund, Jan 2012 –May 2014.
  10. £1,490,550, Medical Research Council. MICA: STELAR (Study Team for Early Life Asthma Research) consortium - Asthma e-lab and identification of novel endotypes of childhood asthma. Sept 2012 – August 2016. MR/K001035/1
  11. £5,000. Ex vivo assessment of the mucolytic and antibacterial capacity of Lynovex. Scottish Enterprise November 2012-April 2013
  12. Cowie H, Reis S, Semple S, Riddell K. Urban Air Quality Citizen Science Programme. Scottish Environmental Protection Agency. 2013. £28,720.
  13. Hilton S, Semple S, Duffy S. Children’s exposure to second-hand tobacco smoke: An analysis of newspaper coverage 2002-2012. Does it tell us about the direction future policy should be going? Cancer Research UK. 2013-2014. £20,517.
  14. Hilton S, Semple S, Duffy S. Children’s exposure to second-hand tobacco smoke: A pilot coding of newspaper coverage. Scottish School of Public Health. 2013. £8,500.
Current Publications

Papers

  1. Smith S, Fielding S, Murchie P, Johnston M, Wyke S, Powell R, Devereux G, Nicolson M, Macleod U, Wilson P, Ritchie L, Lee AJ, Campbell NC. Reducing the time before consulting with symptoms of lung cancer: a randomised controlled trial in primary care. Br J Gen Pract 2013 ;63:24-25
  2. Miller DR. Mydin HH. Marshall AD. Devereux GS. Currie GP. Fatal haemorrhage following endobronchial ultrasound-transbronchial needle aspiration: an unfortunate first. Quarterly J Med 2013; 106:295-6.
  3. Nurmatov U, Tagieva N, Semple S, Devereux G, Sheikh A. Volatile organic compounds and risk of asthma and allergy: a systematic review and meta-analysis of observational and interventional studies. Primary Care Respiratory Journal  2013; 22:PS9-PS15
  4. Kurmi OP, Devereux GS, Smith WCS, Semple S, Steiner MFC, Simkhada P, Lam KH, Ayres JG. Reduced lung function due to biomass smoke exposure in young adults in rural Nepal. Eur Respir J. 2013; 41:25-30
  5. Al-Makoshi A, Al-Frayh A, Turner S, Devereux G. Breastfeeding practice and its association with respiratory symptoms and atopic disease in 1-3 year old children in the City of Riyadh, Central Saudi Arabia. Breast Feeding Medicine. Breastfeeding Medicine, 2013 8:127-33.
  6. Larsen PS, Kamper-Jørgensen M, Adamson A, Barros H, Bonde JP, Brescianini S, Brophy S, Casas M, Charles M-A, Devereux G, et al.  Birth cohort resources in Europe: a large opportunity for aetiological child health research. Paediatric and Perinatal Epidemiology 2013;27:393-414..
  7. Devereux G, Tagiyeva N, Turner SW, Ayres JG, Seaton A, Hudson G, Hough RL, Campbell CD, Shand CA. Early-life residential exposure to soil components in rural areas and childhood respiratory health and allergy. Science of Total Environment. 2014; 466-467: 338-344.
  8. Wassall HJH, Devereux G, Seaton A, Barker RN. Complex effects of vitamin E and vitamin C supplementation on in vitro neonatal mononuclear cell responses to allergens. Nutrients  2013, 5, 3337-3351.
  9. Nwaru B, Craig L, Allan K, Prabhu N, Turner S, McNeill G, Erkkola, M, Seaton A, Devereux G. Breastfeeding and introduction of complementary foods during infancy in relation to the risk of asthma and atopic diseases up to 10 years. Clin Exp Allergy 2013;43:1263-73. Chosen as Editor’s choice for the month..
  10. Sewell DA, Hammersley VS, Devereux G, Robertson A, Stoddart A, Weir C, Worth A, Sheikh A. Investigating the effectiveness of the Mediterranean diet in pregnant women for the primary prevention of asthma and allergy in high-risk infants: protocol for a pilot randomised controlled trial. Trials 2013; 14:173.
  11. Albarbarawi O,  Barton A,  Miller D,  McSharry C, Chaudhuri R, Thomson NC, Palmer CN,  Devereux G. Huang JT. Characterization and validation of an isotope-dilution LC-MS/MS method for quantification of total desmosine and isodesmosine in plasma and serum. Bioanalysis 2013; 5:1991-2001.
  12. Grose D, Devereux G, Brown L, Jones R, Sharma D, Selby C,  Morrison D, Docherty K, McIntosh D, McElhinney P, Nicolson M, Milroy R.Simple and objective prediction of survival in patients with lung cancer; staging the host systemic inflammatory response.,". Lung Cancer International
  13. Targett K, Bourke S, Nash E, Murphy E, Ayres J, Devereux G.The physical and psychological factors associated with employment in adults with cystic fibrosis; a cross-sectional survey. Occupational Medicine (In press).
  14. Doust E, Ayres JG, Devereux G, Dick F, Crawford JO, Cowie H, Dixon K. Is pesticide exposure a cause of obstructive airways disease? A systematic review. European Respiratory Review. (in press).
  15. Nurmatov U, Devereux G, Worth A, Healy L, Sheikh A. Effectiveness, and safety of orally-administered immunotherapy for food allergy: systematic review and meta-analysis. Br J Clin Nutr (In press).
  16. Scaife A, Miller D,  Spiteri-Cornish D, Turner SW, Devereux GS, Walsh GM. Inhibitory effects of Montelukast on mediator release by nasal epithelial cells from asthmatic subjects with or without allergic rhinitis. Respiratory Medicine  2013 Dec;107(12):1859-65
  17. Miller D, Turner SW, Spiteri-Cornish D, McInnes N, Scaife A, Danielian PJ, Farooq M , Devereux G, Walsh GM. Culture of airway epithelial cells from neonates sampled 48 hours of birth. PLoS ONE  2013 Nov 4;8(11):e78321.
  18. Kurmi OP,  Smith WCS, Devereux GS, Sadhra S, Semple S, Steiner MFC, Lam KBH, Simkhada P, Ayres JG.  Indoor air pollution - Biomass smoke - Cardiovascular risk - Systolic blood pressure - Diastolic blood pressure - Hypertension. Int J Publ Health Res (In press).
  19. Sonnenschein-van der Voort AMM, Arens LR, Jongste JC, Annesi-maesano I, Barros H, Basterrechea M, Bisgaard H, Chatzi L, Corpeleijn E, Correia S, Craig LC, Devereux G et al. Preterm birth, birth weight and infant growth and the risk of childhood asthma: a meta-analysis of 31 birth cohorts.  J Allergy Clin Immunol  (In press).
  20. Gahire S, Miller J, Semple S, Turner SW.  Carbon dioxide concentration, school attendance and educational attainment.  Journal of School health. (in press).
  21. Smith S, Craig LC, Raja EA, McNeill G, Turner SW.Prevalence and year-on-year trends in childhood thinness in a whole population study.  Arch Dis Child 2014;99:58-61
  22. Saunders SP, Goh CS, Brown SJ, Palmer CN, Porter RM, Cole C, Campbell LE, Gierlinski M, Barton GJ, Schneider G, Balmain A, Prescott AR, Weidinger S, Baurecht H, Kabesch M, Gieger C, Lee YA, Tavendale R, Mukhopadhyay S, Turner SW, Madhok VB, Sullivan FM, Relton C, Burn J, Meggitt S, Smith CH, Allen MA, Barker JN, Reynolds NJ, Cordell HJ, Irvine AD, McLean WH, Sandilands A, Fallon PG. Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects.  J Allergy Clin Immunol 2013;132:1121-9.
  23. Midulla F, Lombardi E, Carlsen KC, Regamey N, Grigg J, Ross Russell RI, Turner SW, Prifitis K, Eber E.  Paediatrics in Vienna.  Eur Respir J. 2013;42:1092-1104.
  24. Semple S, Ibrahim AE, Apsley A, Steiner M, Turner S. Using a new, low-cost air quality sensor to quantify second-hand smoke (SHS) levels in homes. Tob Control 2013doi: 10.1136/tobaccocontrol-2013-051188
  25. Ritchie DD, Amos A, Shaw S, O’Donnell R, Semple S, Turner S, Martin C.  How do policy advisors and practitioners prioritise the protection of children from second hand smoke exposure in a country with advances tobacco control policy?  Tobacco Control 2013 doi: 10.1136/tobaccocontrol-2012-050936
  26. Cutts R, Turner SW. 'Longitudinal measurements of exhaled nitric oxide in children–what is a significant change in FENO? Paediatr Allergy Immunol 2013;24:540-548
  27. Turner SW, Carter J, Chalmers I, Pacitti N, MacConaghy L, Booth NA. Proteolytic activity in amniotic fluid at term and early childhood respiratory symptoms. J Maternal-Fetal Neonatal Med 2013 doi 10.3109/14767058.2013.818647
  28. Smith S, Craig LC, McNeill G, Turner SW.  Growing up before growing out: secular trends in height, weight and obesity in 5-6 year old children born between 1970 and 2006.  Arch Dis Child. 2013;98:269-273
  29. Friend A, Craig LC, Turner SW.  The Prevalence of Metabolic Syndrome in Children – a Systematic Review of the Literature.  Metabol Syndrome Rel Disorder. 2013;11:71-80
  30. Mullane D, Turner S, Cox D, Goldblatt J, Landau L, le Souef P. Reduced infant lung function, active smoking and wheeze in eighteen year olds.  JAMA Pediatr 2013; 167:368-73
  31. Wilson IS, Ritchie D, Amos A, Shaw A, O’Donnell R, Mills LM, Semple SE Turner SW.  ‘I’m not doing this for me’: mothers’ accounts of creating smoke-free homes.  Health Education Research. 2013; 28:165-7
  32. Turner S. Research activity, barriers and competencies among senior paediatricians in Scotland.  Arch Dis Child 2014;99:91-93
  33. Turner SW. Predicting the future for recurrent respiratory symptoms in young children: Applying a dash of science to the art of medicine.  J Allergy Clin Immunol.  2013. doi:10.1016/j.jaci.2013.07.001
  34. Ross JA, Macdiarmid JI, Semple S, Watt SJ, Moir G, Henderson G. Cognitive Symptoms and Welding Fume Exposure. Ann Occup Hyg. 2013;57:26-33.
  35. Gee IL, Semple S, Watson A, Crossfield A. Nearly 85% of tobacco smoke is invisible--a confirmation of previous claims. Tob Control. 2013;22(6):429.
  36. Tagiyeva N, Anua SM, Semple S, Dick F, Devereux G. The 'take home' burden of workplace sensitizers: flour contamination in bakers' families. Environ Int. 2012;46:44-9.
  37. Semple S, Apsley A, MacCalman L. An inexpensive particle monitor for smoker behaviour modification in homes. Tob Control. 2012 Sep 26. [Epub ahead of print].
  38. Shaw A, Ritchie D, O'Donnell R, Amos A, Mills LM, Semple SE, Turner SW, Wilson IS. Creating smoke-free homes for children. Nurs Times. 2013 Mar 12-18;109(10):28-30.
  39. Galea KS, Hurley JF, Cowie H, Shafrir AL, Sánchez Jiménez A, Semple S, Ayres JG, Coggins M. Using PM2.5 concentrations to estimate the health burden from solid fuel combustion, with application to Irish and Scottish homes. Environ Health. 2013 Jun 19;12:50.
  40. Abidin EZ, Hashim Z, Semple S. Second-Hand Smoke in Public Spaces: How Effective has Partial Smoke-Free Legislation Been in Malaysia? Asian Pac J Cancer Prev. 2013;14(11):6845-50.
  41. Ng MG, de Poot S, Schmid K, Cowie H, Semple S, van Tongeren M. A preliminary comparison of three dermal exposure sampling methods: rinses, wipes and cotton gloves. Environ Sci Process Impacts. 2013 Dec 18;16(1):141-7.
  42. Semple S, Ibrahim AE, Apsley A, Steiner M, Turner S. Using a new, low-cost air quality sensor to quantify second-hand smoke (SHS) levels in homes. Tob Control. 2013 Sep 17. doi: 10.1136/tobaccocontrol-2013-051188. [Epub ahead of print].
  43. Frasch HF, Dotson GS, Bunge AL, Chen CP, Cherrie JW, Kasting GB, Kissel JC, Sahmel J, Semple S, Wilkinson S. Analysis of finite dose dermal absorption data: Implications for dermal exposure assessment. J Expo Sci Environ Epidemiol. 2014 Jan;24(1):65-73.
  44. Paudyal P, Ayres JG, Semple S, Macfarlane GJ. Low back pain among textile workers: a cross-sectional study. Occup Med (Lond). 2013;63(2):129-34.
  45. Gorman Ng M, de Poot S, Schmid K, Cowie H, Semple S, van Tongeren M. Properties of liquids and dusts: how do they influence dermal loading during immersion, deposition, and surface contact exposure pathways? Ann Occup Hyg. 2013;57(5):627-39.

Book chapters/Reviews

  1. Devereux G, Prabhu N. Asthma and Allergic disease, in Nutrition and development: long and short term consequences for health. J Buttriss. London, Blackwells .
  2. Devereux G. Landmark Papers in Allergy, Edited by Aziz Sheikh, Thomas Platts-Mills, and Allison Worth, Stephen Holgate. OUP 2013
  3. Devereux G . Middleton's Allergy. Principles and Practice. 8th Edition. Eds: N. Franklin Adkinson, Bruce S Bochner,  A Wesley Burks, William W Busse, Stephen T Holgate, Robert F Lemanske, Robyn E O'Hehir, ISBN: 978-0-323-08593-9
  4. Turner SW.  Acute and Chronic Lung Infections- Epidemiology.  European Respiratory Society Paediatric Respiratory Medicine Handbook   2013. 
  5. Turner SW.  Paediatric Respiratory Medicine.  European Respiratory Society White Book. 2013
  6. Stenson B and Turner SW.  Macleod’s Clinical Examination.  2013.  Examination of infants and children
  7. Walsh G.M. (2013) Antihistamines (H1 receptor antagonists). Side Effects of Drugs Annual 35 Ed J.K. Aronson, Elsevier, (in press)
  8. Walsh G.M. (2013) Eosinophil Apoptosis and Clearance in Asthma. Journal of Cell Death 6, 17–25
  9. Walsh G.M. (2013) An update on biologic-based therapy in asthma. Immunotherapy 5(11):1255-64.
  10. Walsh G.M. (2013) Therapeutic Potential of Targeting Interleukin 5 in Asthma. BioDrugs 27:559–5630.
  11. Walsh G.M. (2013) Profile of reslizumab in eosinophilic disease and its potential in the treatment of poorly controlled eosinophilic asthma.  Biologics: Targets and Therapy 7, 7–11.