Professor Graham Devereux

Professor Graham Devereux
Professor Graham Devereux
Professor Graham Devereux

MA, BM, BCh, MD, PhD, FRCP(Ed)

Personal Chair (Clinical)

About

Child Health Royal Aberdeen Children's Hospital Aberdeen AB25 2ZG

Biography

Graham Devereux studied as an undergraduate at Cambridge and then Oxford Universities and trained in respiratory medicine in Newcastle, Nottingham and Aberdeen. Whilst in Newcastle he completed his MD thesis describing an epidemiological study of asthma prevalence in the North of England. After completing his clinical training in Aberdeen he completed a PhD thesis identifying antenatal influences on cord blood mononuclear cell responses. In addition to general clinical respiratory duties he has a subspecialist interest in airway diseases such as asthma, COPD and Cystic Fibrosis. His research interests include the identification of antenatal influences on the development of airways disease, but more recently he has become involved in clinical trials. 

Research

Research Overview

Research interests include the identification of antenatal influences on the development of airways disease and he is the principal investigator of the SEATON birth cohort study investigating associations between maternal diet during pregnancy and childhood asthma and allergy. He has published on the associations between childhood asthma and maternal diet, maternal smoking, parental occupation and fetal growth.

More recently he has become involved in clinical trials. he is Co-chief investigator for the NIHR HTA funded trial of low dose theophylline in COPD (TWICS) that has recruited 1578 people with COPD from 170 sites in the UK. He is working closely with Novabiotics to repurpose the drug cysteamine for use in people with cystic fibrosis, he has been/is chief investigator for several trials in this area. In the near future he will be co-chief investigator of the NIHR HTA funded trial of bisoprolol in COPD (BICS).

Publications

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  • Evolution of Eczema, Wheeze, and Rhinitis from Infancy to Early Adulthood Four Birth Cohort Studies

    Haider, S., Fontanella, S., Ullah, A., Turner, S., Simpson, A., Roberts, G., Murray, C. S., Holloway, J. W., Curtin, J. A., Cullinan, P., Arshad, S. H., Hurault, G., Granell, R., Custovic, A., Ainsworth, J., Boyd, A., Bush, A., Couch, P., Devereux, G., Emam, I., Guo, Y. K., Saglani, S., Woodcock, A., STELAR/UNICORN investigators
    American journal of respiratory and critical care medicine, vol. 206, no. 8, pp. 950-960
    Contributions to Journals: Articles
  • Modeling Wheezing Spells Identifies Phenotypes with Different Outcomes and Genetic Associates

    Haider, S., Granell, R., Curtin, J., Fontanella, S., Cucco, A., Turner, S., Simpson, A., Roberts, G., Murray, C. S., Holloway, J. W., Devereux, G., Cullinan, P., Arshad, S. H., Custovic, A.
    American journal of respiratory and critical care medicine, vol. 205, no. 8, pp. 883-893
    Contributions to Journals: Articles
  • Use of the oral beta blocker bisoprolol to reduce the rate of exacerbation in people with chronic obstructive pulmonary disease (COPD): a randomised controlled trial. (BICS)

    Cotton, S., Devereux, G., Abbas, H., Briggs, A. H., Campbell, K., Chaudhuri, R., Choudhury, G., Dawson, D., De Soyza, A., Fielding, S., Gompertz, S., Haughney, J., Lang, C. C., Lee, A., MacLennan, G., MacNee, W., McCormack, K., McMeekin, N., Mills, N. L., Morice, A., Norrie, J., Petrie, L., Price, D., Short, P., Vestbo, J., Walker, P., Wedzicha, J. A., Wilson, A., Lipworth, B. J.
    Trials, vol. 23, no. 1, 307
    Contributions to Journals: Articles
  • Spirometric phenotypes from early childhood to young adulthood: a Chronic Airway Disease Early Stratification study

    Wang, G., Hallberg, J., Charalampopoulos, D., Sanahuja, M. C., Breyer-Kohansal, R., Langhammer, A., Granell, R., Vonk, J. M., Mian, A., Olvera, N., Laustsen, L. M., Rönmark, E., Abellan, A., Agusti, A., Arshad, S. H., Bergström, A., Boezen, H. M., Breyer, M. K., Burghuber, O., Bolund, A. C., Custovic, A., Devereux, G., Donaldson, G. C., Duijts, L., Esplugues, A., Faner, R., Ballester, F., Garcia-Aymerich, J., Gehring, U., Haider, S., Hartl, S., Backman, H., Holloway, J. W., Koppelman, G. H., Lertxundi, A., Holmen, T. L., Lowe, L., Mensink-Bout, S. M., Murray, C. S., Roberts, G., Hedman, L., Schlünssen, V., Sigsgaard, T., Simpson, A., Sunyer, J., Torrent, M., Turner, S., Van den Berge, M., Vermeulen, R. C., Vikjord, S. A. A., CADSET Clinical Research Collaboration
    ERJ Open Research, vol. 7, no. 4, 00457
    Contributions to Journals: Articles
  • Maternal iron supplementation in pregnancy and asthma in the offspring: Follow-up of a randomised trial in Finland

    Shaheen, S. O., Gissler, M., Gissler, M., Devereux, G., Erkkola, M., Kinnunen, T. I., Mcardle, H., Sheikh, A., Hemminki, E., Nwaru, B. I., Nwaru, B. I., Nwaru, B. I., Nwaru, B. I.
    European Respiratory Journal, vol. 55, no. 6, 1902335
    Contributions to Journals: Letters
  • Low-dose oral theophylline combined with inhaled corticosteroids for people with chronic obstructive pulmonary disease and high risk of exacerbations: a RCT

    Devereux, G., Cotton, S., Fielding, S., McMeekin, N., Barnes, P. J., Briggs, A., Burns, G., Chaudhuri, R., Chrystyn, H., Davies, L., Soyza, A. D., Gompertz, S., Haughney, J., Innes, K., Kaniewska, J., Lee, A., Morice, A., Norrie, J., Sullivan, A., Wilson, A., Price, D.
    Health technology assessment (Winchester, England), vol. 23, no. 37, pp. 1-146
    Contributions to Journals: Articles
  • Distinguishing wheezing phenotypes from infancy to adolescence: A pooled analysis of five birth cohorts

    Oksel, C., Granell, R., Haider, S., Fontanella, S., Simpson, A., Turner, S., Devereux, G., Arshad, S. H., Murray, C. S., Roberts, G., Holloway, J. W., Cullinan, P., Henderson, J., Custovic, A.
    Annals of the American Thoracic Society, vol. 16, no. 7, pp. 868-876
    Contributions to Journals: Articles
  • Maternal vitamin D and E intakes in pregnancy and asthma to age 15 years: A cohort study

    Devereux, G., Craig, L., Seaton, A., Turner, S.
    Pediatric Pulmonology, vol. 54, no. 1, pp. 11-19
    Contributions to Journals: Articles
  • Temporarily quadrupling the dose of inhaled steroid to prevent asthma exacerbations: FAST

    McKeever, T., Mortimer, K., Bradshaw, L., Haydock, R., Pavord, I., Higgins, B., Walker, S., Wilson, A., Price, D., Thomas, M., Devereux, G., Brightling, C., Renwick, C., Parrott, S., Mitchell, E., Duley, L., Harrison, T.
    Health Technology Assessment, vol. 22, no. 70, pp. 1-82
    Contributions to Journals: Articles
  • Effect of Theophylline as Adjunct to Inhaled Corticosteroids on Exacerbations in Patients With COPD: A Randomized Clinical Trial

    Devereux, G., Cotton, S., Fielding, S., McMeekin, N., Barnes, P. J., Briggs, A., Burns, G., Chaudhuri, R., Chrystyn, H., Davies, L., De Soyza, A., Gompertz, S., Haughney, J., Innes, K., Kaniewska, J., Lee, A., Morice, A., Norrie, J., Sullivan, A., Wilson, A., Price, D.
    JAMA, vol. 320, no. 15, pp. 1548-1559
    Contributions to Journals: Articles
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