The aim of eTHoS is to establish the effectiveness and cost-effectiveness of stapled haemorrhoidpexy (SH) compared with traditional excisional haemorrhoidectomy (TH). At present there is no evidence that tells us which of these types of surgery is best for patients who have haemorrhoids that require surgery.

This multi-centre trial, funded by the National Institute for Health Research (NIHR) Health Technology Assessment (HTA) Programme, will recruit 800 patients (400 to SH and 400 to TH). Patients who require surgical treatment to improve symptoms with circumferential haemorrhoids grade II, III and IV can take part. 

The study will run over 72 months, with the primary outcome being patient reported overall health related quality of life over a period of two years. 

eTHoS study websiteEthos Trial Logo


Jessica Wood;