Intervention modelling experiments (IMEs) allow complex interventions to be explored and refined prior to a full-scale trial by delivering key elements of the intervention in a simulation that approximates clinical practice. This project, funded by the CSO, builds on previous CSO-funded work by running a full, web-based IME (WIME) to advance the methodology of IMEs by directly comparing results with an earlier paper-based IME. The WIME targets inappropriate prescribing of antibiotics in primary care. First, we compare predictors of prescribing behaviour obtained from the WIME with those obtained in the paper-based IME. Second, we use a randomised design to compare the effects on simulated prescribing behaviour of a previously-developed intervention with a new intervention developed specifically for web-based delivery.


Shaun Treweek;