This project has been commissioned but the NIHR Systematic Reviews Programme to assess the current evidence on the effects and safety of any interventions which aim to alleviate the symptoms of painful bladder syndrome (interstitial cystitis) in adults.

There is currently no definitive cure for painful bladder syndrome and treatment options, which aim to alleviate symptoms, include surgery, pharmacological treatments, supportive/conservative therapies, and lifestyle recommendations. As part of the project, we will conduct a network meta-analysis to estimate treatment effects for different clinical interventions.

The results of this project will inform clinical practice and policy on the most effective options for treating the symptoms of painful bladder and help to identify future primary research opportunities for the NHS. In addition, the findings of this project will contribute to the development of an evidence synthesis, which will be published in the Cochrane Library.

For further information see


Miriam Brazzelli;