Systematic review of the efficacy and safety of using mesh or grafts in surgery for uterine or vaginal wall proplase

Summary

This systematic review was conducted as part of the HSRU Review Body for Interventional Procedures (ReBIP) project supported by theNational Institute for Health and Clinical Excellence (NICE) Interventional Procedures Programme

Based on the information provided in this review on the safety and efficacy of sacrocolpopexy using mesh for vaginal vault prolapse repair, the Committee found that the evidence appeared to be adequate to support the use of this procedure provided that normal arrangements were in place for clinical governance and audit (sacrocolpopexy using mesh for vaginal vault prolapse repair, IPG283). 

However, the review also provided evidence for four other surgical procedures using mesh in women with uterine or vault prolapse surgery: 

In all four cases, the Committee found that the current evidence on the safety and efficacy was inadequate in quantity and quality. Therefore these procedures should only be used with special arrangements for clinical governance, consent and audit or research.  Partly in response, the HSRU / CHaRT trial VUE was funded to provide this evidence. 

Contact

Cathryn Glazener; c.glazener@abdn.ac.uk (member of review team)

Status

Complete

Publications

Jia X, Glazener C, Mowatt G, Jenkinson DJ, Fraser C, Bain C, Burr JM. Systematic review of the efficacy and safety of using mesh in surgery for uterine or vaginal vault prolapse. Int Urogynecol J Pelvic Floor Dysf  2010;21(11):1413-31.