Systematic reviews can provide the best evidence on the effectiveness of interventions. The optimal design and conduct of reviews is often complex and continually evolves.  We aim to develop and promote new methodologies for the design, conduct and reporting of knowledge syntheses.

A number of projects have investigated methods of conducting reviews such as empirical studies of different searching strategies and evaluation of risk of bias tools for nonrandomised studies.  Several members of HSRU lead advanced training courses and seminars.

  • The methodological handbook for the NICE Interventional Procedures Programme was developed in partnership with the Review Body for Interventional Procedures
  • Methods for reviewing nonrandomised studies have been integrated into the Cochrane Handbook
  • Training courses in review methodologies are regularly undertaken at National and International fora

Current collaborators include the Statistical and Non-randomised studies methods groups of the Cochrane Collaboration and the Agency for Healthcare Research and Quality.


Craig Ramsay;

MRC Search Filters Performance Project (MRC SFP)