This systematic review of the evidence on the safety and efficacy of foam sclerotherapy concluded that it appears to be efficacious in treating all types of superficial venous disease, including both main trunk and minor vein disease. While local adverse events associated with the procedure were relatively common, serious adverse events including stroke and myocardial infarction, grand malepileptic fit, pulmonary embolism and deep vein thrombosis were statistically rare. Adverse events such as visual disturbance, transient confusion, and other systemic symptoms were reported in rates of less than 6%.
This systematic review was undertaken on behalf of NICE‘s Interventional Procedures programme and was updated in 2013 by NICE.
Cynthia Fraser; firstname.lastname@example.org
Jia X, Mowatt G, Burr JM, Cassar K, Cook JA, Fraser C. Systematic review of the safety and efficacy of foam sclerotherapy for venous disease of the lower limbs. Br J Surg 2007;94(8):925-36.