The primary aim of this NIHR HTA-funded project is to assess the current evidence for the clinical effectiveness and cost-effectiveness of surveillance imaging strategies following endovascular repair (EVAR) of an abdominal aortic aneurysm. EVAR is a minimally invasive technique but is associated with potential complications, thus patients require lifelong surveillance following the procedure. Computed tomography angiography (CTA) is widely used but carries the risk of repeated exposure to radiation and to a toxic contrast agent. The use of ultrasound has been suggested as a possible, safer alternative. The imaging technologies under evaluation are colour duplex ultrasound (CDU) or contrast-enhanced ultrasound (CEU), alone or in conjunction with plain film X-ray, compared with computed tomography angiography (CTA). We are conducting a systematic review of the literature; considering data from national and international registries and relevant clinical databases; developing a model based economic evaluation to represent possible alternative surveillance strategies modelled at varying surveillance intervals; and recording the personal experience of two patient representatives. The results of the project will inform clinical practice and policy on the optimal surveillance strategy after EVAR.
Miriam Brazzelli email@example.com
Data Collection - Ongoing
Brazzelli, M, Hernandez, R, Sharma, P, Robertson, C, Shimonovich, M, MacLennan, G, Fraser, C, Jamieson, R, Vallabhaneni, S The clinical and cost-effectiveness of protocols using contrast-enhanced ultrasound and/or colour duplex ultrasound in the long-term surveillance of endovascular abdominal aortic aneurysm repair: an evidence synthesis and economic evaluation. Health Technol Assess 2017 (accepted for publication)