The clinical effectiveness and cost effectiveness of rapid point of care tests for the detection of genital Chlamydia infection in women and men: systematic review and economic evaluation
This study involved a systematic review of the diagnostic performance and effectiveness of point of care tests and the incorporation of these data into a simple economic model. Current practice was found to be less costly and more effective, although there were circumstances under which point-of-care testing could become a viable alternative (i.e. if uptake rates for testing were increased using this point-of-care method).
Outcome and Translation
There was insufficient evidence to suggest that the Chlamydia Rapid Test could improve detection of genital Chlamydia infection compared with current practice. Therefore there is no evidence to support the use of this test by the NHS at the present time. Further research examining uptake and return rates was recommended, along with research on the acceptability of point-of-care testing.
HERU resreachers involved in this research project: Luke Vale (HERU/HSRU); Zahidul Quayyum
External collaborators: J Hislop and G Mowatt (HSRU, University of Aberdeen)
Hislop, J., Quayyum, Z., Flett, G., Boachie, C., Fraser, C. and Mowatt, G. (2010) 'Systematic review of the clinical effectiveness and cost-effectiveness of rapid point-of-care tests for the detection of genital chlamydia infection in women and men', Health technology Assessment, 14(29).
Quayyum, Z. (2011) 'Rapid point-of-care tests for the detection of genital chlamydia infection in women and men: is it a cost-effective option for NHS?' HERU Briefing Paper, University of Aberdeen, July 2011.
Hislop, J. and Quayyum, Z. (2010) 'Creating realistic scenarios for sensitivity analysis in economic evaluation - applying parameter data from a different setting: a case study on chlamydia testing', 7th Annual Health Technology Assessment International, Dublin, June 2010.