Long term follow up for VUE - Vault or Uterine prolapse surgery Evaluation: two parallel randomised controlled trials of surgical options for upper compartment (uterine or vault) pelvic organ prolapse
Gynaecologists have recognised for some time that both anatomical failure and recurrence of prolapse symptoms after surgery are common: one in three women who have a prolapse operation will go on to have another, though not necessarily in the same compartment. More recently, it has also been recognised that surgery can be followed by a greater impairment of quality of life than from the original prolapse itself (for example the development of new-onset urinary incontinence after surgery or prolapse at a different site). Whilst anterior and posterior prolapse surgery is most common (90% of operations), around 43% of women also have a uterine (34%) or vault (9%) procedure at the same time. Indeed, this demonstrates that women who have a hysterectomy have around a 27% chance of needing a subsequent vault prolapse repair.
This extended follow-up of women randomised to the VUE trial is being conducted to better inform lomg-term clinical and cost – effectiveness of the alternative surgical procedures.
HERU researchers involved in this research project: Mary Kilonzo
External collaborators: C. Glazener, S. Breeman, G. McPherson, A. McDonald, J. Norrie, A. Elders (Health Services Research Unit (HSRU), University of Aberdeen); I.B.G. Montgomery (Aberdeen); S. Hagen (Glasgow Caledonian University); A.R.B. Smith (St. Mary’s Hospital Manchester); R.M. Freeman (Plymouth Hospital NHS Trust); C. Bain, K. Cooper (NHS Grampian).