BSRBR-AS: British Society for Rheumatology Biologics Register in Ankylosing Spondylitis
The British Society for Rheumatology Biologics Register – Ankylosing Spondylitis (BSRBR-AS) was established to monitor the safety of biologic treatments for patients with AS and to determine how such treatments affect symptoms, function, co-morbidities and quality of life. The study is a prospective cohort enrolling two groups of patients meeting international criteria for AS and who are naïve to biologic therapy: those commencing biologic therapy (etanercept or adalimumab) and those who are not commencing biologic therapy.
HERU researchers involved in this research project: Paul McNamee
External collaborators: G Macfarlane, G Jones (Other Applied Health Sciences, University of Aberdeen); K Hyrich, K Watson, M Lunt, D Symmons (Arthritis Research UK Epidemiology Unit, University of Manchester); R Sturrock (Centre for Rheumatic Diseases, University of Glasgow); L Kay (Freeman Hospital, Newcastle) and A Neilson (University of Edinburgh)
Macfarlane, G. J., Barnish, M. S., Jones, E. A., Kay, L., Keat, A., Meldrum, K. T., Pathan, E., Sturrock, R.D., Zabke, C., McNamee, P. and Jones, G. T. (2015) ‘The British Society for Rheumatology Biologics Registers in Ankylosing Spondylitis (BSRBR-AS) study: protocol for a prospective cohort study of the long-term safety and quality of life outcomes of biologic treatment', BMC Musculoskeletal Disorders, 16(1), 347.
Neilson, A.R., Jones, G., Macfarlane, G., Pathan, E. and McNamee, P. (2017) 'Real-world health-related quality of life ED-5D-5L outcomes in Ankylosing Spondylitis (AS): analysis of data from the UK British Society for Rheumatology Register in Ankylosing Spondylitis (BSRBR-AS) study', International Society for Pharmacoeconomics and Outcomes Research (ISPOR) 20th Annual Congress, Scottish Event Campus, Glasgow, 4-8 November 2017.
Jones, G., Macfarlane, G., Pathan, E., McNamee, P. and Neilson, A.R. (2018) 'Quality of life estimation in economic evaluations and healthcare decision making: different approaches, different results. Results from the British Society for Rheumatology Biologics Register in Ankylosing Spondylitis (BSRBR-AS)' [Poster], British Society for Rheumatology Annual Conference, Liverpool, 1-3 May 2018.
Jones, G., Macfarlane, G., Pathan, E., McNamee, P. and Neilson, A.R. (2018) 'Health utility estimates in economic evaluations in axial spondyloarthritis: different methods, different results', 11th Congress on Spondyloarthritides Gent, Belgium, 4-6 October 2018.