The clinical effectiveness and cost-effectiveness of computed tomography screening for lung cancer: systematic reviews
Black, C., Bain, L., Thomas, S., Waugh, N. (Department of Population Health, University of Aberdeen) Ayres, J., Godden, D. (Division of Applied Health Sciences, University of Aberdeen), Bagust, A. (University of Liverpool Management School) Boland, A., McLeod, C. (Liverpool Reviews and Implementation Group, University of Liverpool) and Walker, S. (Department of Radiology, Aberdeen Royal Infirmary)
Early detection and successful treatment of lung cancer has the potential to save countless lives. Lung cancer is the leading cause of death from cancer in the UK, killing approximately 34,000 people per year. Screening would be attractive if it could detect presymptomatic lung cancer at a stage when surgical intervention is feasible. The study assessed the effectiveness and cost-effectiveness of computed tomography screening in the detection of lung cancer by taking into account the effect of mortality, detection of early disease and the impact on quality of life in order to assist policy making and to assist to clarify research needs. Separate narrative reviews were performed for the clinical and cost-effectiveness.
Black, C., Bagust, A., Boland, A., Walker, S., McLeod, C.,de Verteuil, R., Ayres, J., Bain, L., Thomas, S., Godden, D. and Waugh, N. The clinical effectiveness and cost-effectiveness of computed tomography screening for lung cancer: systematic reviews. Health Technology Assessment. 2006; 10(3)
Black, C.,de Verteuil, R., Walker, S., Ayres, J., Boland, A., Bagust, A. and Waugh, N. Population screening for lung cancer using CT, is there evidence of clinical effectiveness? A systematic review of the literature. Thorax. 2007; 62(2): 131-138.