SPECT cost effectiveness and probabilistic sensitivity analyses

SPECT cost effectiveness and probabilistic sensitivity analyses


Hernández, R., McKenzie, L. (HERU) and Vale, L. (HERU/HSRU)


Coronary heart disease (CHD) is the commonest cause of death in the UK, causing over 120,000 deaths in 2001. CAD is the commonest cause of CHD. Strategies involving SPECT with and without Stress Electrocardiography (EGC), and Coronary Angiography (CA), were compared to diagnostic strategies not involving SPECT. To make informed decision based on cost effectiveness it is important to know not only if a particular test is cost effective but also the degree of imprecision of those results. This project built upon previous work in the area and assessed the statistical imprecision around cost effectiveness results obtained in a previously developed economic model. Unlike earlier evaluations this study included a probabilistic analysis in which the statistical imprecision of the results was assessed.


R Hernández




Hernández, R.and Vale, L. The value of myocardial perfusion scintigraphy in the diagnosis and management of angina and myocardial infarction: a probabilistic economic analysis. Medical Decision Making. 2007; 27(6): 772-788.