FILMS

Randomised comparison of macular hole surgery with or without internal limiting membrane peeling (FILMS)

Investigators

Lois, N. (Grampian University Hospitals Trust), Burr, J., Norrie, J. (HSRU, University of Aberdeen) and Vale, L. (HERU)

Summary

A randomised controlled trial in patients with stage 2-3 FTMH was conducted. Patients were recruited from centres throughout the UK and Ireland. Patients were followed up for 6 months and health service costs and QALYs (derived from the EQ-5D) were estimated.

The study found that Peeling was associated with small but not statistically significant improvements in QALYs and more substantial reductions in cost, which again did not reach conventional levels of statistical significance. However, there was over a 90% chance that peeling would be considered cost-effective.

Contact

G Scotland

Status

Complete

Publications

Lois, N., Burr, J., Norrie, J., Vale, L., Cook, J. and McDonald, A. The Full-thickness macular hole and Internal Limiting Membrane peeling Study (FILMS) Group. Clinical and cost-effectiveness of internal limiting membrane peeling for patients with idiopathic full thickness macular hole. Protocol for a Randomised Controlled Trial: FILMS (Full-thickness macular hole and Internal Limiting Membrane peeling Study). Trials. 2008, Nov 3; 9(1):61.

Lois, N., Burr, J., Norrie, J., Vale, L., Cook, J., McDonald, A. and Ternent, L. Clinical and cost-effectiveness of internal limiting membrane peeling for patients with idiopathic full thickness macular hole. Final grant report submitted to Chief Scientist Office. September 2009.

Presentations

-FILMS

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