OTIS:  Prospective collaborative study of patients with intestinal segments transposed into urinary tract following surgery for bladder cancer or benign end-stage bladder disease

Each year in the UK around 3,000 people have major surgery because their bladders are seriously diseased or must be removed. This prospective study compared the various surgical options using transposed intestinal segments and established sufficiently large observational cohorts to allow statistically reliable comparisons between the surgical procedures. Outcomes measured were quality of life and requirements for other healthcare resources, up to at least one year after the index procedure. Approximately 600 patients were recruited from 10 hospitals in Great Britain.

Outcome and Translation

This study informed the relative effectiveness and efficiency of alternative treatments for patients undergoing bladder surgery.

Click here for further details on this project

HERU researchers involved in this research project: Rodolfo Hernández

External Collaborators: J N’Dow and A Grant (HSRU, University of Aberdeen)

Publications 

OTIS Study Team (Hernández, R. is a member of the study team) (forthcoming) Prospective collaborative study of patients with intestinal segments transposed into urinary tract following surgery for bladder cancer or benign end-stage bladder disease (OTIS). Final report submitted to BUPA.