This course considers the development of neural structures, their plasticity when mature and their regenerative capacity when damaged. Topics include axon growth mechanisms, guidance, cell recognition, cell death, synaptogenesis and development of skeletal muscle and its innervation. Neural plasticity and interactions with the environment are examined by reviewing the development of mammalian sensory systems over a critical period. Plasticity in the adult covers mechanisms of learning and memory, central and peripheral nerve and muscle regeneration following injury and some examples of disease states (eg metabolic neuropathies and myopathies, muscular dystrophy, ageing and dementia). The course consists of 4 lectures and 1 laboratory session (lasting 8 hours) per week. It is examined by continuous assessment of practical work and essays, and a 3-hour written exam.

Pre-requisites : BM3001 or PA3001 or PY3001 or (AN3002 and AN3003 and AN3004 and AN3501) or (BM3002 and BM3003 and BM3004 and BM3005)

Course Organiser : Dr. Colin McCaig (ext. 3012) c.mcaig@abdn.ac.uk