Generation of antibody or peptide hits through
phage display is an invaluable tool for biological research as these recombinant antibodies/peptides bind specifically to their targets and can be easily expressed in bacterial or mammalian systems. Using phage display, the antigen binding regions of an antibody (variable heavy and light chain genes) are isolated and conveniently
reformatted into soluble antibody fragments or full monoclonal antibodies. These biological ligands can be used in a number of applications including;
Disease marker discovery
Drug target validation
Diagnostics (clinical to environmental samples)
In vivo imaging
Therapeutic candidates