Dr Margaret Cruickshank

Dr Margaret Cruickshank The University of Aberdeen School of Medicine & Dentistry Senior Lecturer (Clinical Consultant) work +44 (0)1224 438434 work +44 (0)1224 553470 work +44 (0)1224 553069 work fax 01224 553200 pref m.e.cruickshank@abdn.ac.uk pref MacGillivray Academic Centre Aberdeen Maternity Hospital ABERDEEN AB25 2ZD

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Research Interests

I have  a programme of research in pre-invasive disease of the lower genital tract,clinical research trials and molecular studies in collaboration with Universities of Edinburgh, Dundee, Cambridge, Nottingham and Strathclyde and NHS Scotland.  The focus of this work relates to Human Papilloma virus infection (HPV).   

 

 

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Collaborations

The collaborators in our resrach programme  have set up a Scottish HPV Investigators Research Network (SHINe) to promote collaboration and the development of HPV research.  This includes the development of a national HPV archive funded by CSO BTR programme grant and collaboration to optimise our research strategy with the HPV surveillance work of Health Protection Scotland.

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Teaching Responsibilities

Dr Maggie Cruickshank is responsible for the planning and co-ordination of Phase IV (Final Year) of the MB ChB course  and participates in specialist teaching in Obstetrics and Gynaecology, including co-ordination of the Phase III Reproductive Health block.

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Publications

Contributions to Journals

Articles

• Higgins, C. & Cruickshank, M. (2012). 'A population based case control study of aetiological factors associated with vulval lichen sclerosus'. Journal of Obstetrics and Gynaecology, vol 32, no. 3, pp. 271-275.
• Gurumurthy, M., Morah, N., Gioffre, G. & Cruickshank, M. (in press). 'The surgical management of complications of vulval lichen sclerosus'. European Journal of Obstetrics & Gynecology and Reproductive Biology.
• Sharp, L., Cotton, S., Thornton, A., Gray, NM., Whynes, D., Smart, L., Waugh, N., Duncan, I., Cruickshank, M. & Little, J. (in press). 'Which women default from follow-up cervical cytology tests?: A cohort study within the TOMBOLA trial'. Cytopathology.
  [Online] DOI: 10.1111/j.1365-2303.2011.00848.x
• Cotton, S., Sharp, L., Cochran, C., Gray, N., Cruickshank, M., Smart, L., Thornton, A. & Little, J. (2011). 'After-effects reported by women having follow-up cervical cytology tests in primary care: a cohort study within the TOMBOLA trial'. British Journal of General Practice, vol 61, no. 587, pp. e333-e339.
  [Online] DOI: 10.3399/bjgp11X578007
• Cotton, SC., Sharp, L., Little, J., Cruickshank, ME., Seth, R., Smart, L., Duncan, I., Harrild, KA., Neal, K., Waugh, NR. & The TOMBOLA Group (2010). 'The role of human papillomavirus testing in the management of women with low-grade abnormalities: multicentre randomised controlled trial'. BJOG-An International Journal of Obstetrics and Gynaecology, vol 117, no. 6, pp. 645-659.
  [Online] DOI: 10.1111/j.1471-0528.2010.02519.x
• Cairns, M., Cuschieri, KS., Cubie, HA. & Cruickshank, ME. (2010). 'High-Risk HPV Genotyping in the Follow-Up of Women Treated Conservatively for Microinvasive Cervical Cancer'. International Journal of Gynecological Cancer, vol 20, no. 1, pp. 154-157.
  [Online] DOI: 10.1111/IGC.0b013e3181c3a6b6
• Gurumurthy, M., Cairns, M. & Cruickshank, ME. (2010). 'Case Series of Zoon Vulvitis'. Journal of Lower Genital Tract Disease, vol 14, no. 1, pp. 56-58.
  [Online] DOI: 10.1097/LGT.0b013e3181afd524
• Milingos, DS., Harry, V. & Cruickshank, ME. (2010). 'The Clinically Suspicious Cervix-How Often Is It Cancer?'. Journal of Lower Genital Tract Disease, vol 14, no. 3, pp. 196-199.
  [Online] DOI: 10.1097/LGT.0b013e3181cb4c7d
• Whynes, D., Philips, Z., Woolley, C., Cotton, SC., Cruickshank, ME., Harrild, KA., Little, J., Sharp, L., Waugh, NR. & The TOMBOLA Group (2009). 'Cytological surveillance compared with immediate referral for colposcopy in management of women with low grade cervical abnormalities: multicentre randomised controlled trial'. British Medical Journal, vol 339, pp. b2546.
  [Online] DOI: 10.1136/bmj.b2546
• Sharp, L., Cotton, SC., Cochran, C., Gray, NM., Little, J., Neal, K., Cruickshank, ME. & The TOMBOLA (Trial Of Management of Borderline and Other Low-grade Abnormal smears) Group (2009). 'After-effects reported by women following colposcopy, cervical biopsies and LLETZ: results from the TOMBOLA trial'. BJOG: An International Journal of Obstetrics and Gynaecology, vol 116, no. 11, pp. 1506-1514.
  [Online] DOI: 10.1111/j.1471-0528.2009.02263.x
• McFadden, KM., Sharp, L. & Cruickshank, ME. (2009). 'The prospective management of women with newly diagnosed vulva intraepithelial neoplasia: clinical outcome and quality of life'. Journal of Obstetrics and Gynaecology, vol 29, no. 8, pp. 749-753.
• Shanbhag, S., Clark, H., Timmaraju, V., Bhattacharya, S. & Cruickshank, ME. (2009). 'Pregnancy outcome after treatment for cervical intraepithelial neoplasia'. Obstetrics & Gynecology, vol 114, no. 4, pp. 727-35.
  [Online] DOI: 10.1097/AOG.0b013e3181b5cba3
• Sharp, L., Cruickshank, ME., Little, J., Cotton, SC., Harrild, KA., Cochran, C., Waugh, NR., Smart, L. & TOMBOLA Group (2009). 'Biopsy and selective recall is as effective as immediate LLETZ in the management of women with low-grade smears referred for colposcopy'. British Medical Journal, vol 339, pp. 2548.
• Whynes, D., Philips, Z., Woolley, C., Cotton, SC., Harrild, KA., Cruickshank, ME., Little, J., Smart, L., Waugh, NR. & TOMBOLA group (2009). 'Options for managing low grade cervical abnormalities detected at screening: cost effectiveness study'. British Medical Journal, vol 339, pp. 2549.
  [Online] DOI: 10.1136/bmj.b2549
• Shehmar, M., Finn, C., Peile, E., Redman, C. & Cruickshank, ME. (2009). 'A Validity Study of The National UK Colposcopy Objective Structured Clinical Examination - Is it a test fit for purpose?'. British Journal of Obstetrics and Gynaecology, vol 116, no. 13, pp. 1796-1800.
• Cairns, M., Gray, NM. & Cruickshank, M. (2008). 'The impact of microinvasive cancer of the cervix on women during follow-up'. International Journal of Gynecological Cancer, vol 18, no. 6, pp. 1289-1293.
  [Online] DOI: 10.1111/j.1525-1438.2007.01186.x
• Kitchener, H., Walker, P., Nelson, L., Hadwin, R., Patnick, J., Moore, C. & Cruickshank, ME. (2008). 'HPV testing as an adjunct to cytology in the follow-up of women treated for cervical intraepithelial neoplasia'. British Journal of Obstetrics and Gynaecology, vol 115, no. 8, pp. 1001-1007.
• Cairns, M. & Cruickshank, ME. (2007). 'A Review of Women With Microinvasive Cervical Cancer in the Grampian Region'. Journal of Lower Genital Tract Disease, vol 11, no. 4, pp. 290-293.
  [Online] DOI: 10.1097/LGT.0b013e31804f5a93
• Cotton, SC., Sharp, L., Seth, R., Masson, LF., Little, J., Cruickshank, ME., Neal, K., Waugh, NR. & TOMBOLA Group (2007). 'Lifestyle and sociodemographic factors associated with high-risk HPV infection in UK women'. British Journal of Cancer, vol 97, no. 1, pp. 133-139.
  [Online] DOI: 10.1038/sj.bjc.6603822
• Harry, V., Cruickshank, ME. & Parkin, D. (2007). 'Auditing the Use of Colposcopy Versus General Gynecology Clinics to Investigate Women With Postcoital or Intermenstrual Bleeding: A Case for a New Outpatient Service'. Journal of Lower Genital Tract Disease, vol 11, no. 2, pp. 108-111.
  [Online] DOI: 10.1097/01.lgt.0000245049.67965.39
• Thangaratinam, S., Walker, PW., Freeman-Wang, T., Luesley, D., Cruickshank, ME. & Redman, C. (2007). 'Identifying the Performance Criteria for Appraisal of Colposcopists: Benchmarking Delphi'. BJOG: An International Journal of Obstetrics and Gynaecology, vol 114, no. 10, pp. 1288-1291.
  [Online] DOI: 10.1111/j.1471-0528.2007.01442.x
• Gray, NM., sharp, L., Cotton, SC., Masson, LF., little, J., Walker, LG., Avis, M., Philips, Z., Russell, I., Whynes, DK., Cruickshank, ME., Woolley, CM. & The TOMBOLA Group (2006). 'Psychological effects of a low-grade abnormal cervical smear test result:anxiety and associated factors'. British Journal of Cancer, vol 94, pp. 1253-1262.
  [Online] DOI: 10.1038/sj.bjc.6603086
• Bentley, E., Cotton, SC., Cruickshank, ME., Duncan, I., Gray, NM., Jenkins, D., little, J., Neal, K., Philips, Z., Russell, I., Seth, R., sharp, L. & Waugh, NR. (2006). 'Refining the management of low-grade cervical abnormailities in the UK National Health Service and defining the potential for human papillomavirus testing: A commentary on emerging evidence'. Journal of Lower Genital Tract Disease, vol 10, no. 1, pp. 26-38.
  [Online] DOI: 10.1097/01.lgt.0000192695.93172.75
• Cotton, SC., Sharp, L., Little, J., Cruickshank, ME. & TOMBOLA Group (2006). 'Trial of management of borderline and other low grade abnormal smears (TOMBOLA): Trial design'. Contemporary Clinical Trials, vol 27, no. 5, pp. 449-471.
  [Online] DOI: 10.1016/j.cct.2006.04.001
• Parkin, D., Warraich, Q., Fleming, DJ., Chew, GK. & Cruickshank, ME. (2006). 'An audit of the quality of endometrial cancer care in a specialised unit'. Scottish Medical Journal, vol 51, no. 2, pp. 22-24.
• Harry, V., Lyall, M., Cruickshank, ME. & Parkin, D. (2006). 'Cervical amyloidosis: a rare cause of Post menopausal bleeding'. European Journal of Obstetrics & Gynecology and Reproductive Biology, vol 137, no. 2, pp. 252-253.
• Narayansingh, GV., Miller, ID., Sharma, M., Welch, CJ., Sharp, L., Parkin, DE. & Cruickshank, ME. (2005). 'The prognostic significance of micrometastases in node-negative squamous cell carcinoma of the vulva'. British Journal of Cancer, vol 92, pp. 222-224.
  [Online] DOI: 10.1038/sj.bjc.6602343
• Chew, GK., Cruickshank, M., Rooney, PH., Miller, ID., Parkin, D. & Murray, GI. (2005). 'Human Papillomavirus 16 infection in adenocarcinoma of the cervix'. British Journal of Cancer, vol 93, no. 11, pp. 1301-1304.
  [Online] DOI: 10.1038/sj.bjc.6602855
• Cruickshank, ME., Anthony, GB., Fitzmaurice, AE., McConnell, D., Graham, WJ., Alexander, DA., Tunstall, ME. & Ross, JAS. (2005). 'A randomised controlled trial to evaluate the effect of self administereed analgesia on women's experience of outpatient treatment at colposcopy'. BJOG-An International Journal of Obstetrics and Gynaecology, vol 112, no. 12, pp. 1652-1658.
  [Online] DOI: 10.1111/j.1471-0528.2005.00782.x
• Flannelly, G., Monaghan, J., Cruickshank, ME., Duncan, I., Johnson, J., Jordan, J., Campbell, MK. & Patnick, J. (2004). 'Cervical screening in women over the age of 50: results of a population-based multicentre study'. BJOG-An International Journal of Obstetrics and Gynaecology, vol 111, no. 4, pp. 362-368.
  [Online] DOI: 10.1111/j.1471-0528.2004.00085.x
• Flannelly, G., Monaghan, J., Cruickshank, ME., Duncan, I., Johnston, J., jordan, J., Campbell, MK. & Patnick, J. (2004). 'Cervical screening in women over the age of fifty: results of a population based multicentre study'. British Journal of Obstetrics and Gynaecology, vol 111, no. 4, pp. 362.
• McNally, O., Delaney, EK., Petty, RD., Hutcheon, AW., Cruickshank, ME. & Parkin, D. (2003). 'Is optimal first line chemotherapy deliverable in all newly diagnosed ovarian cancers. A population based study'. British Journal of Cancer, vol 89, pp. 966-967.
  [Online] DOI: 10.1038/sj.bjc.6601071
• Cruickshank, ME., Sharp, L., Murray, GI. & Smart, L. (2002). 'Persistent infection with human papillomavirus following the successful treatment of high grade cervical intraepithelial neoplasia'. BJOG-An International Journal of Obstetrics and Gynaecology, vol 109, no. 5, pp. 579-581.
  [Online] DOI: 10.1111/j.1471-0528.2002.01554.x
• Cruickshank, ME., Chambers, G., Murray, GI., McKenzie, L., Donaldson, C., Andrews, J., Campbell, MK. & Kitchener, H. (2002). 'Age-restricted cervical screening: HPV testing at age 50 identifies a high risk group for cervical disease'. International Journal of Gynecological Cancer, vol 12, no. 6, pp. 735-740.
  [Online] DOI: 10.1046/j.1525-1438.2002.01116.x
• Chew, GK. & Cruickshank, ME. (2001). 'Human papillomavirus as a form of risk assessment'. Best Practice & Research in Clinical Obstetrics & Gynaecology, vol 15, no. 5, pp. 759-768.
  [Online] DOI: 10.1053/beog.2001.0218
• McFadyen, MCE., Cruickshank, ME., Miller, ID., McLeod, HL., Melvin, WT., Haites, NE., Parkin, D. & Murray, GI. (2001). 'Cytochrome P450 CYP1B1 over-expression in primary and metastatic ovarian cancer'. British Journal of Cancer, vol 85, no. 2, pp. 242-246.
  [Online] DOI: 10.1054/bjoc.2001.1907
• Cruickshank, ME., Angus, VC., Kelly, M., McPhee, S. & Kitchener, HC. (1997). 'The case for stopping cervical screening at age 50'. British Journal of Obstetrics and Gynaecology, vol 104, no. 5, pp. 586-589.

Scientific Reviews

• James, R., Cruickshank, ME. & Siddiqui, N. (2008). 'Management of Cervical Cancer: Summary of SIGN Guidelines'. British Medical Journal, vol 336, pp. 41-43.
• Cairns, M. & Cruickshank, ME. (2006). 'Treatment and follow-up of women with micro invasive cervical cancer'. Reviews in Gynaecological Practice, vol 6, no. 3-4, pp. 126-132.
  [Online] DOI: 10.1016/j.rigapp.2006.05.001

Editorials

• Cruickshank, ME. (2005). 'What does HPV mean for the postmenopausal woman?'. Papillomavirus Report, vol 16, no. 5, pp. 320-321.
  [Online] DOI: 10.1179/095741905X69717
• McFadden, KM. & Cruickshank, ME. (2005). 'New developments in the management of VIN (Review)'. Reviews in Gynaecological Practice, vol 5, pp. 102-108.
  [Online] DOI: 10.1016/j.rigp.2005.04.002

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