Dr Thomas Baddeley

Dr Thomas Baddeley The University of Aberdeen School of Medicine & Dentistry Dr Thomas Baddeley Research Fellow work +44 (0)1224 272947

Research Fellow

Dr Thomas Baddeley

Personal Details

Telephone: +44 (0)1224 272947
Email: t.c.baddeley@abdn.ac.uk
hCard

Research Interests

The development and use of new analytical methods in the study of small organic molecules undergoing clinical evaluation.

The synthesis and study of novel organic compounds for use as potential drug candiates and excipients.

The study of the physical properties of novel oligosaccharides


^ top

Selected Publications

  • Storey,J. M. D.; Sinclair,J.; Marshall,C.; Wischik,C. M.; Sinclair,J.; Baddeley,T. Methods of synthesis and/or purification of diaminophenothiazinium compounds, Patent Published, EP2057136 (A2), Published 13May 2009.
  • Thomas C. Baddeley and James L. Wardell, Synthesis of Per- and Poly-Substituted Trehalose Derivatives: Studies of Properties Relevant to Their Use as Excipients for Controlled Drug Release Journal of Carbohydrate Chemistry, (2009), 28, 198–221 
  • Thomas C. Baddeley, Luciana de Souza Franca, R. Alan Howie, Geraldo M. de Lima, Janet M. S. Skakle,Jose Dias de Souza, James L. Wardell; and Solange M. S. V. Wardell 2-Hydroxyacetophenone arylhydrazones. Supramolecular arrangements based on C––H… O(H), C––H… O(NO), N––H… O(H), N––H… O(NO), C––H… p or p … p interactions, Z. Kristallogr. (2009), 224, 213–224.
  • Wischik,C. M.; Rickard,J. E.; Harrington,C. R.; Horsley,D.; Storey,J. M. D.; Marshall,C.; Sinclair,J.; Baddeley,T. Case 12 3-7 Diamino - IOH phenothiazine salts and their uses, Chapter in Book, in press, US CIP.
  • Thomas C. Baddeley, Jairo Bordinhão, Nadia M. Comerlato, Laila de Castro Cortás, Glaucio B. Ferreira, R. Alan Howie and James L. Wardell Studies of distannylated-1,2-dithiolato compounds: Synthesis of 4,5-bis[(triorganostannylmethyl)thiolato]-1,3-dithiole-2-thiones, (R3SnCH2)2(dmit), and 4,5-bis[(triorganostannylmethyl)thiolato]-1,3-dithiole-2-ones, (R3SnCH2)2(dmio) – Crystal structures of (Ph3SnCH2)2(dmit) and (Ph3SnCH2)2(dmio), Journal of Organometallic Chemistry, (2007),692, Issue 25, 5583-5588.
  • Thomas C. Baddeley, William T. A. Harrison, R. Alan Howie, Janet M. S. Skakle and James L. Wardell Co-crystallised α- and β-Anomers of 2,3,4,6-Tetra-acetyl-d -glucopyranose, in which the α- and β-Anomers are Randomly Distributed in the Hydrogen-bonded Chains of Molecules, Journal of Chemical Crystallography. (2007) 37, 853-858.
  • Kyeremeh,K.; Baddeley,T.; Stein,B. K.; Jaspars,M. A homologous series of eunicellin-based diterpenes from Acalycigorgia sp. characterised by tandem mass spectrometry, Original Article in Peer Reviewed Journal, 2006, Tetrahedron, 62, pp8770 - 8778, ISSN/ISBN: 0040-4020
  • T. C. Baddeley, R. A. Howie, J. M. S. Skakle and J. L. Wardell 1,2,3,4-Tetra-O-acetyl-b-D-glucopyranuronic acid monohydrate at 120K and anhydrous 1,2,3,4-tetra-O-acetyl-b-D-glucopyranose at 292K, Acta Cryst. (2005), C61, o711-o714.
  • T. C. Baddeley, I. G. Davidson, C. Glidewell, J. N. Low, J. M. S. Skakle and J. L. Wardell Supramolecular structures of substituted a,a'-trehalose derivatives, Acta Cryst. (2004), B60, 461-471.
  • T. C. Baddeley, I. G. Davidson, J. M. S. Skakle and J. L. Wardell Ethyl 1,2,3,4-tetra-O-acetyl-b-D-glucopyranuronate, Journal of Chemical Crystallography. (2003). 33, 33-38.
  • T. C. Baddeley, S. M. Clow, P. J. Cox, I. G. Davidson, A. M. Murdoch and J. L. Wardell Disordered 2,2',3,3',4,6,6'-hepta-O-pivaloyl-a,a'-trehalose,Acta Cryst. (2003), E59, o753-o755
  • T. C. Baddeley, S. M. Clow, P. J. Cox, I. G. Davidson, C. Ryder and J. L. Wardell Disordered 4,4'-di-O-isobutyroyl-2,2',3,3',6,6'-hex-O-acetyl-a,a'-trehalose, Acta Cryst. (2003), E59, o848-o850
  • T. C. Baddeley, I. G. Davidson, J. M. S. Skakle and J. L. Wardell 1,2,3,4-Tetra-O-acetyl-b-D-glucopyranuronamide, Acta Cryst. (2002), E58, o447-o449
  • T. C. Baddeley, S. M. Clow, P. J. Cox, I. G. Davidson, R. A. Howie and J. L. Wardell Ditrityl-a,a'-trehalose hexaacetate, Acta Cryst. (2002), E58, o476-o477
  • T. C. Baddeley, S. M. Clow, P. J. Cox, A. M. McLaughlin and J. L. Wardell a,a'-Trehalose octaacetate ethyl acetate solvate, Acta Cryst. (2001), E57, o456-o457.

 


^ top

update

‹ back