Scottish Biologics Facility

Biologic ligands including classical monoclonal antibodies (and their fragments), peptides and alternative binding scaffolds are invaluable tools for biomarker validation, diagnostic assay development, in vivo imaging and drug discovery. Using phage display technology, large antibody or protein libraries can be selected and screened for target binding, by displaying binding sites on the surface of bacteriophage. The SULSA-supported Scottish Biologics Facility (SBF) at the University of Aberdeen will offer antibody-library screening services against a wide range of targets including proteins, peptides and haptens. In addition, SULSA-researchers will be able to gain training in phage display based selection, screening techniques, antibody reformatting etc. through the experienced technologist working within the facility. The facility has recently increased its staff and has moved to new facilities on the University of Aberdeen's Forseterhill site. The process of establishing suitable protocols for antibody selection is now well underway. It is anticipated that the facility will be able to offer antibody selection as part of the next round of SULSA Translational Biology Screening (Q2 2010).

Website

www.abdn.ac.uk/sbf/

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