Musculoskeletal Programme: http://www.abdn.ac.uk/ims/research/musculoskeletal-175.php
Stuart graduated in Physiology and Sports Science from the University of Glasgow before undertaking a PhD entitled "Temperature and in vivo human skeletal muscle function and metabolism" at the University of Strathclyde(2007). During his doctoral studies Stuart was awarded the Pfizer Prize from the Physiological Society in 2005. Stuart remained at the University of Strathclyde as a Post-Doctoral Research Fellow before moving to Loughborough University to take up a Senior Research-Associate position. Stuart joined the institute of medical sciences in November 2008 as a Lecturer in Exercise Physiology.
Stuart has two main areas of interest.
With age there is a natural loss of muscle mass that is termed sarcopenia and this can have major effects on physical function and quality of life in the elderly. The precise cause of the loss of muscle mass is not yet known, but we do know that elderly muscles exhibit an anabolic resistance to exercise and food intake. We are currently investigating whether an increase in n3 PUFA consumption, particularly fish oils, can augment the adaptive response to resistance exercise in the elderly. Preliminary results have shown that fish oils can retard the loss of muscle mass with age in a rat model and that this effect is potentially mediated through an increase activity of p70s6k, a key regulator of protein synthesis.
We are also interested in determining the effects of high intensity exercise on post prandial lipaemia and activation of the immune system. Upon the consumption of a high fat meal triglycerides enter the blood stream and can trigger a series of inflammatory reactions that ultimately results in endothelial dysfunction, a precursor for the development of atherosclerosis. It is known that exercise can reduce the magnitude of this response but the optimal and most time efficient form of exercise has yet to be determined. We are also interested in extending this research to patient populations where post prandial lipaemia is a contributing factor to disease progression.
Dr Henning Wackerhage
Dr Aivaras Ratkevicius
Dr Arimantas Lionikas
Dr Frank Thies
Professor Michael Frenneaux
2010-11 NHS Grampian Endowments. Gray SR and Frenneaux M. The effect of short duration high intensity interval exercise on post-prandial lipaemia and adhesion molecules. £4,025
2010-11 Tenovus Scotland. Gray SR and Thies F. The effect of fish oil supplementation on immune function and inflammatory responses to execise. £7,575
2010-2013 Saltire Energy Studentship. Gray SR and Ratkevicius A. High intensity exercise and metabolic regulation. £85,896
2012-13 NHS Grampian Endowments. Ratkevicius A and Gray SR. Citrate synthase as a target in the treatment of lipotoxicity in skeletal muscle cells. £8,000
2012-2015 BBSRC New Investigator. Gray SR. Overcoming the blunted response to resistance exercise with fish oil to maximise the maintenance of muscle mass in older people. £330,684
I currently teach on the following courses.
SR2501 (Course Co-ordinator)
PY3002 (Course Co-ordinator)
SR4004/5 (Course Co-ordinator)
Ad Hoc reviewer for the Cytokine, Endocrine, Acta Physiologica, Journal of Sports Sciences, International Journal of Sports Nutrition and Exercise Metabolism, Preventive Medicine, Applied Physiology Nutrtion and Metabolism, Scandinavian Journal of Medicine and Science in Sports, PLoS ONE, AGE, Obesity, British Journal of Pharmacology, Metabolism, Molecular Nutrition and Food Research, Lipids, BMC Research Notes, Clinical Science and the European Journal of Applied Physiology.
Reviewer for grant applications submitted to BBSRC, BHF and BUPA.
I have recently acted as a mentor for secondary school pupils taking part in the "Science of Sport: How to Win Gold" competition organised by the Physiological Society. I also recently participated in i'm a scientist get me out of here, where we had online chats with primary school kids who then decided whether we our responses merit their votes. I did not win!
Member of the college of life sciences and medicine ethics review board (CERB).
Health and Safety Adviser for HSB labs and RPS for IMS level 2.
Dr Mariasole Da Boit - Research Fellow working on the BBSRC funded project entitled "the blunted response to resistance exercise with fish oil to maximise the maintenance of muscle mass in older people".
Torkamol Kamolrat - PhD student funded by the Royal Thai government. Torkamol's thesis is investigating the role of EPA/DHA on skeletal muscle anabolic signalling.
Brendan Gabriel - PhD student funded by the Saltire Energy Studentship. Brendan's project is investigating the effect of high intensity exercise on fat metabolism and CV health.
Patrick Gray - Technician/MSc Student. Patrick's thesis is investigating the effect of n3 PUFAs on post exercise immune function.
Nor Aini Jamil - PhD student investigating the role of Vitamin D in bone and muscle health in South East Asian populations living in Aberdeen.