Mr Tiehui Wang

Research Fellow

Personal Details

E-mail:

t.h.wang@abdn.ac.uk

Selected Publications

1. Wang T, Martin SAM & Secombes CJ (2010) Two interleukin-17C-like genes exist in rainbow trout Oncorhynchus mykiss that are differentially expressed and modulated. Dev Comp Immunol. [Epub ahead of print] 2. Wang T, Martin SAM & Secombes CJ (2010) Cloning of a novel interleukin-20 like gene in rainbow trout Oncorhynchus mykiss gives a clue to the evolution of the IL-10 family. Dev Comp Immunol. 34:158-167. 3. Wang, T., Bird, S., Koussounadis, K., Holland, J. W., Carrington, A., Zou, J. & Secombes, C. J. 2009. Identification of a novel IL-1 cytokine family member in teleost fish. J Immunol. 183:962-74. 4. Wang, T., Secombes, C. J. 2009. Identification and expression analysis of two fish-specific IL-6 cytokine family members, the ciliary neurotrophic factor (CNTF)-like and M17 genes, in rainbow trout Oncorhynchus mykiss. Mol Immunol. 46:2290-8. 5. Wang, T., P. C. Hanington, M. Belosevic, and C. J. Secombes. 2008. Two macrophage colony-stimulating factor genes exist in fish that differ in gene organization and are differentially expressed. J Immunol 181:3310-3322. 6. Wang, T., and C. J. Secombes. 2008. Rainbow trout suppressor of cytokine signalling (SOCS)-1, 2 and 3: molecular identification, expression and modulation. Mol Immunol 45:1449-1457. 7. Wang, T., J. W. Holland, A. Carrington, J. Zou, and C. J. Secombes. 2007. Molecular and functional characterization of IL-15 in rainbow trout Oncorhynchus mykiss: a potent inducer of IFN-gamma expression in spleen leukocytes. J Immunol 179:1475-1488. 8. Hanington, P. C., T. Wang, C. J. Secombes, and M. Belosevic. 2007. Growth factors of lower vertebrates: characterization of goldfish (Carassius auratus L.) macrophage colony-stimulating factor-1. J Biol Chem 282:31865-31872. 9. Wang, T., J. W. Holland, N. Bols, and C. J. Secombes. 2005. Cloning and expression of the first nonmammalian interleukin-11 gene in rainbow trout Oncorhynchus mykiss. Febs J 272:1136-1147. 10. Boshra, H., T. Wang, L. Hove-Madsen, J. Hansen, J. Li, A. Matlapudi, C. J. Secombes, L. Tort, and J. O. Sunyer. 2005. Characterization of a C3a receptor in rainbow trout and Xenopus: the first identification of C3a receptors in nonmammalian species. J Immunol 175:2427-2437. 11. Wang, T., N. Johnson, J. Zou, N. Bols, and C. J. Secombes. 2004. Sequencing and expression of the second allele of the interleukin-1beta1 gene in rainbow trout (Oncorhynchus mykiss): identification of a novel SINE in the third intron. Fish Shellfish Immunol 16:335-358. 12. Wang, T., and C. J. Secombes. 2003. Complete sequencing and expression of three complement components, C1r, C4 and C1 inhibitor, of the classical activation pathway of the complement system in rainbow trout Oncorhynchus mykiss. Immunogenetics 55:615-628. 13. Wang, T., J. Zou, C. Cunningham, and C. J. Secombes. 2002. Cloning and functional characterisation of the interleukin-1 beta 1 promoter of rainbow trout (Oncorhynchus mykiss). Biochim Biophys Acta 1575:108-116. 14. Wang, T., M. Ward, P. Grabowski, and C. J. Secombes. 2001. Molecular cloning, gene organization and expression of rainbow trout (Oncorhynchus mykiss) inducible nitric oxide synthase (iNOS) gene. Biochem J 358:747-755.

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Publications

Bruijn, Id., Belmonte, R., Anderson, VL., Saraiva, M., Wang, T., van West, Pv. & Secombes, CJ. Immune Gene Expression in Trout Cell Lines Infected with the Fish Pathogenic Oomycete Saprolegnia Parasitica, Article, 2012, Developmental and Comparative Immunology, ISSN/ISBN: 0145-305X
Chang, M., Wang, T., Nie, P., Zou, J. & Secombes, CJ. Cloning of two rainbow trout nucleotide-binding oligomerization domain containing 2 (NOD2) splice variants and functional characterization of the NOD2 effector domains, Article, 2011, Fish & Shellfish Immunology, 30, 1, pp118 - 127, ISSN/ISBN: 1050-4648
Wang, T., Diaz-Rosales, P., Costa, M., Martin, S., Campbell, S., Snow, M., Collet, B. & Secombes, C. Functional characterization of a nonmammalian IL-21, Article, 2011, Journal of Immunology, 186, 2, pp708 - 721, ISSN/ISBN: 0022-1767
Wang, T., Huang, W., Costa, M., Martin, S. & Secombes, C. Two copies of the genes encoding the subunits of putative interleukin (IL)-4/IL-13 receptors, IL-4Ra, IL-13Ra1 and IL-13Ra2, have been identified in rainbow trout (Oncorhynchus mykiss) and have complex patterns of expression and modulation, Article, 2011, Immunogenetics, 63, 4, pp235 - 253, ISSN/ISBN: 0093-7711
Wang, T., Diaz-Rosales, P., Martin, SAM. & Secombes, CJ. Cloning of a novel interleukin (IL)-20-like gene in rainbow trout Oncorhynchus mykiss gives an insight into the evolution of the IL-10 family, Article, 2010, Developmental and Comparative Immunology, 34, 2, pp158 - 167, ISSN/ISBN: 0145-305X
Wang, T., Monte, M., Huang, W., boudinot, P., Martin, SAM. & Secombes, CJ. Identification of two FoxP3 genes in rainbow trout (Oncorhynchus mykiss) that are differentially expressed and modulated., Article, 2010, Molecular Immunology, In Press, ISSN/ISBN: 0161-5890
Holland, JW., Karim, A., Wang, T., Alnabulsi, A., Scott, J., Collet, B., Mughal, MS., Secombes, CJ. & Bird, S. Molecular cloning and characterization of interferon regulatory factors 4 and 8 (IRF-4 and IRF-8) in rainbow trout, Oncorhynchus mykiss, Article, 2010, Fish & Shellfish Immunology, 29, 1, pp157 - 166, ISSN/ISBN: 1050-4648
Wang, T., Holland, J., Martin, S. & Secombes, C. Sequence and expression analysis of two T helper master transcription factors, T-bet and GATA3, in rainbow trout Oncorhynchus mykiss and analysis of their expression during bacterial and parasitic infection, Article, 2010, Fish & Shellfish Immunology, 29, 5, pp705 - 715, ISSN/ISBN: 1050-4648
Wang, T., Martin, SAM. & Secombes, CJ. Two interleukin-17C-like genes exist in rainbow trout Oncorhynchus mykiss that are differentially expressed and modulated, Article, 2010, Developmental and Comparative Immunology, 34, 5, pp491 - 500, ISSN/ISBN: 0145-305X
Casadei, E., Wang, T., Zou, J., Vecino, JLG., Wadsworth, S. & Secombes, CJ. Characterization of three novel beta-defensin antimicrobial peptides in rainbow trout (Oncorhynchus mykiss), Article, 2009, Molecular Immunology, 46, 16, pp3358 - 3366, ISSN/ISBN: 0161-5890
Wang, T., Bird, S., Koussounadis, A., Holland, JW., Carrington, AC., Zou, J. & Secombes, CJ. Identification of a Novel IL-1 Cytokine Family Member in Teleost Fish, Article, 2009, Journal of Immunology, 183, 2, pp962 - 974, ISSN/ISBN: 0022-1767
Oestergaard, AE., Martin, SAM., Wang, T., Stet, RJM. & Secombes, CJ. Rainbow trout (Oncorhynchus mykiss) possess multiple novel immunoglobulin-like transcripts containing either an ITAM or ITIMs, Article, 2009, Immunology, 125, pp83 - 83, ISSN/ISBN: 0019-2805
Diaz-Rosales, P., Bird, S., Wang, T., Fujiki, K., Davidson, WS., Zou, J. & Secombes, CJ. Rainbow trout interleukin-2, Article, 2009, Fish & Shellfish Immunology, 27, 3, pp414 - 422, ISSN/ISBN: 1050-4648
Gao, Q., Nie, P., Thompson, K., Adams, A., Wang, T., Secombes, CJ. & Zou, J. The search for the IFN-gamma receptor in fish, Article, 2009, Developmental and Comparative Immunology, 33, 8, pp920 - 931, ISSN/ISBN: 0145-305X
Holland, JW., Bird, S., Williamson, B., Woudstra, C., Mustafa, A., Wang, T., Zou, J., Blaney, SC., Collet, B. & Secombes, CJ. Molecular characterization of IRF3 and IRF7 in rainbow trout, Oncorhynchus mykiss, Article, 2008, Molecular Immunology, 46, 2, pp269 - 285, ISSN/ISBN: 0161-5890
Wang, T., Holland, JW., Carrington, AC., Zou, J. & Secombes, CJ. Molecular and Functional Characterization of IL-15 in Rainbow Trout Oncorhynchus mykiss, Article, 2007, Journal of Immunology, 179, 3, pp1475 - 1488, ISSN/ISBN: 0022-1767
Chen, KW., Chen, YC., Lo, HJ., Odds, FC., Wang, T., Lin, CY. & Li, SY. Multilocus sequence typing for analyses of clonality of Candida albicans strains in Taiwan, Article, 2006, Journal of Clinical Microbiology, 44, 6, pp2172 - 2178, ISSN/ISBN: 0095-1137
Wang, T., Holland, JW., Bols, N. & Secombes, CJ. Cloning and expression of the first nonmammalian interleukin-11 gene in rainbow trout Oncorhynchus mykiss, Article, 2005, European Journal of Biochemistry, 272, 5, pp1136 - 1147, ISSN/ISBN: 0014-2956
Wang, T., Johnson, N., Zou, J., Bols, N. & Secombes, CJ. Sequencing and expression of the second allele of the interleukin-1 beta 1 gene in rainbow trout (Oncorhynchus mykiss), Article, 2004, Fish & Shellfish Immunology, 16, 3, pp335 - 358, ISSN/ISBN: 1050-4648
Wang, T. & Secombes, CJ. Complete sequencing and expression of three complement components, Clr, C4 and C1 inhibitor, of the classical activation pathway of the complement system in rainbow trout Oncorhynchus mykiss, Article, 2003, Immunogenetics, 55, pp615 - 628, ISSN/ISBN: 0093-7711
Wang, T., Zou, J., Cunningham, C. & Secombes, CJ. Cloning and functional characterisation of the interleukin-1 beta 1 promoter of rainbow trout (Oncorhynchus mykiss), Article, 2002, Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1575, 1-3, pp108 - 116, ISSN/ISBN: 0167-4781
Zou, J., Wang, T., Hirono, I., Aoki, T., Inagawa, H., Honda, T., Soma, GI., Ototake, M., Nakanishi, T., Ellis, BE. & Secombes, CJ. Differential expression of two tumor necrosis factor genes in rainbow trout, Oncorhynchus mykiss, Article, 2002, Developmental and Comparative Immunology, 26, 2, pp161 - 172, ISSN/ISBN: 0145-305X
Bird, S., Zou, J., Wang, T., Munday, B., Cunningham, C. & Secombes, CJ. Evolution of interleukin-1 beta, Scientific review, 2002, Cytokine & Growth Factor Reviews, 13, 6, pp483 - 502, ISSN/ISBN: 1359-6101
Bird, S., Wang, T., Zou, J., Cunningham, C. & Secombes, CJ. The first cytokine sequence within cartilaginous fish: IL-1 beta in the small spotted catshark (Scyliorhinus canicula), Article, 2002, Journal of Immunology, 168, 7, pp3329 - 3340, ISSN/ISBN: 0022-1767
Laing, KJ., Wang, T., Zou, J., Holland, JW., Hong, SH., Bols, N., Hirono, I., Aoki, T. & Secombes, CJ. Cloning and expression analysis of rainbow trout Oncorhynchus mykiss tumour necrosis factor-alpha, Article, 2001, European Journal of Biochemistry, 268, 5, pp1315 - 1322, ISSN/ISBN: 0014-2956
Wang, T. & Secombes, CJ. Cloning and expression of a putative common cytokine receptor gamma chain (gC) gene in rainbow trout (Oncorhynchus mykiss), Article, 2001, Fish & Shellfish Immunology, 11, pp233 - 244, ISSN/ISBN: 1050-4648
Secombes, CJ., Wang, T., Hong, S., Peddie, S., Crampe, M., Laing, KJ., Cunningham, C. & Zou, J. Cytokines and innate immunity of fish, Article, 2001, Developmental and Comparative Immunology, 25, 8-9, pp713 - 723, ISSN/ISBN: 0145-305X
Wang, T., Ward, M., Grabowski, P. & Secombes, CJ. Molecular cloning, gene organization and expression of rainbow trout (Oncorhynchus mykiss) inducible nitric oxide synthase (iNOS) gene, Article, 2001, Biochemical Journal, 358, pp747 - 755, ISSN/ISBN: 0264-6021

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