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Dr Catherine Jones

Senior Lecturer

 

Personal Details

Telephone:

+44 (0)1224 272403

E-mail:

c.s.jones@abdn.ac.uk


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Research Interests

The main focus of my current research is the evolution of parasite resistance, in particular, understanding host-parasite interactions at the molecular level. Research on the evolution of host defence mechanisms involves two main model systems. The first model system is the freshwater snail intermediate host and the causative agent of human schistosomiasis, the trematode Schistosoma spp. Current work spans the fields of population genetics, phylogenetics, the identification, and evolution of snail intermediate hosts, through to developing molecular approaches for the isolation and characterization of genes involved in parasite resistance. This research theme has been extended to include investigations of immune gene expression and parasite resistance in 3 fish systems including sealice, (Lepeophtheirus salmonis) and Gyrodactylus salaris resistance in Atlantic salmon and resistance to Tetracapsula bryosalmonae, PKX, causative agent of Proliferative Kidney Disease, PKD in trout.

An additional line of research is the genetics of sharks involving population genetics of globally distributed sharks such as the great white shark, hammerheads and basking sharks, as well as the study of microsatellite evolution in sharks.  

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Research Grants

2003-2009 Wellcome Trust; 'Biomphalaria glabrata: gene discovery, expression profiling and interval mapping to elucidate mechanisms of resistance to Schistosoma mansoni'. Principal Investigator.  (with Dr L.R Noble).

2004-2006 DEFRA; 'Conservation genetics of basking sharks'. Principal Investigator.(With Dr L.R.Noble).

2001/2004 MAFF. Immune Gene Expression during PKD infection. (With Prof. C. Secombes & Dr L.Noble).

2001/2004 EU Aberdeen University as Coordinators. (SALMOGYRO) The genetic basis of Gryrodactylus salaris Resistance in Altantic salmon (Salmo salar). (With Dr L.Noble).

1997/2002 BBSRC Advanced Fellowship to CSJ. Molecular genetic analysis and evolution of parasite resistance.

1999/ 2003 NERC Link Aquaculture / Scottish Salmon Growers/ Marine Harvest Scotland Identification of disease resistance genes and markers in Atlantic salmon differing in their susceptibility to sealice infection. (With Dr L. Noble & Prof. C. Secombes).

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Publications

  • Cauwelier, E., Gilbey, J., Jones, CS., Noble, LR. & Verspoor, E. Asymmetrical viability in backcrosses between highly divergent populations of Atlantic salmon (Salmo salar), Article, 2012, Conservation Genetics, 13, 6, pp1665 - 1669, ISSN/ISBN: 1566-0621
  • Lockyer, AE., Emery, AM., Kane, RA., Walker, AJ., Mayer, CD., Mitta, G., Coustau, C., Adema, CM., Hanelt, B., Rollinson, D., Noble, LR. & Jones, CS. Early Differential Gene Expression in Haemocytes from Resistant and Susceptible Biomphalaria glabrata Strains in Response to Schistosoma mansoni, Article, 2012, PLoS ONE, 7, 12, ISSN/ISBN: 1932-6203
  • Gubili, C., bilgin, r., kalkan, e., Karhan, U., Jones, CS., Sims, DW., kabasakal, h., martin, a. & Noble, LR. Antipodean white sharks on a Mediterranean walkabout?, Article, 2011, Proceedings of the Royal Society of London. B, Biological Sciences, 278, 1712, pp1679 - 1686, ISSN/ISBN: 0962-8452
  • Cauwelier, E., Gilbey, J., Jones, CS., Noble, LR. & Verspoor, E. Genotypic and phenotypic correlates with proliferative kidney disease-induced mortality in Atlantic salmon, Article, 2010, Diseases of Aquatic Organisms, 89, 2, pp125 - 135, ISSN/ISBN: 0177-5103
  • Campbell, G., Noble, LR., Rollinson, D., Southgate, VR., Webster, JP. & Jones, CS. Low genetic diversity in a snail intermediate host (Biomphalaria pfeifferi Krass, 1848) and schistosomiasis transmission in the Senegal River Basin, Article, 2010, Molecular Ecology, 19, 2, pp241 - 256, ISSN/ISBN: 0962-1083
  • Thieltges, DW., Ferguson, MA., Jones, CS., Noble, LR. & Poulin, R. Biogeographical patterns of marine larval trematode parasites in two intermediate snail hosts in Europe, Article, 2009, Journal of Biogeography, 36, 8, pp1493 - 1501, ISSN/ISBN: 0305-0270
  • Gubili, C., Johnson, R., Gennari, E., Oosthuizen, WH., Kotze, D., Meyer, M., Sims, DW., Jones, CS. & Noble, LR. Concordance of genetic and fin photo identification in the great white shark, Carcharodon carcharias, off Mossel Bay, South Africa, Article, 2009, Marine Biology, 156, 10, pp2199 - 2207, ISSN/ISBN: 0025-3162
  • Thieltges, DW., Ferguson, MA., Jones, CS., Krakau, M., de Montaudouin, X., Noble, LR., Reise, K. & Poulin, R. Distance decay of similarity among parasite communities of three marine invertebrate hosts, Article, 2009, Oecologia, 160, 1, pp163 - 173, ISSN/ISBN: 0029-8549
  • Pade, NG., Queiroz, NM., Humphries, NE., Witt, MJ., Jones, CS., Noble, LR. & Sims, DW. First results from satellite-linked archival tagging of porbeagle shark, Lamna nasus, Article, 2009, Journal of Experimental Marine Biology and Ecology, 370, 1-2, pp64 - 74, ISSN/ISBN: 0022-0981
  • Searle, JB., Jones, CS., Gunduz, I., Scascitelli, M., Jones, EP., Herman, JS., Rambau, RV., Noble, LR., Berry, RJ., Gimenez, MD. & Johannesdottir, F. Of mice and (Viking?) men, Article, 2009, Proceedings of the Royal Society of London. B, Biological Sciences, 276, 1655, pp201 - 207, ISSN/ISBN: 0962-8452
  • Gilbey, J., Cauwelier, E., Jones, CS., Mclay, A., Noble, LR. & Verspoor, E. Size-dependent growth of individual Atlantic salmon Salmo salar alevins from hatch to first feeding, Article, 2009, Journal of Fish Biology, 75, 10, pp2820 - 2831, ISSN/ISBN: 0022-1112
  • Lockyer, AE., Spinks, J., Kane, RA., Hoffmann, KF., Fitzpatrick, JM., Rollinson, D., Noble, LR. & Jones, CS. Biomphalaria glabrata transcriptome, Article, 2008, BMC Genomics, 9 - 634, ISSN/ISBN: 1471-2164
  • Collins, CA., Olstad, K., Sterud, E., Jones, CS., Noble, LR., Mo, TA. & Cunningham, CO. Isolation of a novel fish thymidylate kinase gene, upregulated in Atlantic salmon (Salmo salar L.) following infection with the monogenean parasite Gyrodactylus salaris, Article, 2007, Fish & Shellfish Immunology, 23, 4, pp793 - 807, ISSN/ISBN: 1050-4648
  • Cauwelier, E., Jones, CS., Noble, LR. & Verspoor, E. The genetical architecture of outbreeding depression in Atlantic salmon, Article, 2006, Journal of Fish Biology, 69 - 240, ISSN/ISBN: 0022-1112
  • Gow, J., Noble, LR., Rollinson, D. & Jones, CS. A High incidence of clustered microsatellite mutations revealed by parent-offpring analysis in an African freshwater snail, Bulinus forskalii (Gastropoda, Pulmonata)., Article, 2005, Genetica, 124, pp77 - 83, ISSN/ISBN: 0016-6707
  • Gow, J., Noble, LR., Rollinson, D. & Jones, CS. High levels of selfing are revealed by a parent-offspring analysis of the medically-important freshwater snail, Bulinus forskalii (Gastropoda, Pulmonata)., Article, 2005, Journal of Molluscan Studies, 71, pp175 - 180, ISSN/ISBN: 0260-1230
  • Gow, J., Noble, LR., Rollinson, D., Mimpfoundi, R. & Jones, CS. Breeding system and demography shape population genetic structure across ecological and climatic zones in the African freshwater snail, Bulinus forskalii (Gastropoda, Pulmonata), intermediate host for schistosomes, Article, 2004, Molecular Ecology, 13, 11, pp3561 - 3573, ISSN/ISBN: 0962-1083
  • Maclean, L., Pardini, AT., Noble, LR., Bishop, JDD. & Jones, CS. Polymorphic dinucleotide microsatellite loci in the clonal ascidian Diplosoma listerianum: predominance of compound and highly interrupted imperfect repeats., Article, 2004, Molecular Ecology Notes, 4, 2, pp283 - 285, ISSN/ISBN: 1471-8278
  • Lockyer, AE., Noble, LR., Rollinson, D. & Jones, CS. Schistosoma mansoni: Resistant specific infection-induced gene expression in Biomphalaria glabrata identified by fluorescent-based differential display, Article, 2004, Experimental Parasitology, 107, 1-2, pp97 - 104, ISSN/ISBN: 0014-4894
  • Lockyer, AE., Jones, CS., Noble, LR. & Rollinson, D. Trematodes and snails: an intimate association, Article, 2004, Canadian Journal Of Zoology/Revue Canadien De Zoologie, 82, 2, pp251 - 269, ISSN/ISBN: 0008-4301
  • Emery, AM., Loxton, NJ., Stothard, R., Jones, CS., Spinks, J., Llewellyn-Hughes, J., Noble, LR. & Rollinson, D. Microsatellites in the freshwater snail Bulinus globosus (Gastropoda : Planorbidae) from Zanzibar, Article, 2003, Molecular Ecology Notes, 3, 1, pp108 - 110, ISSN/ISBN: 1471-8278
  • Noble, LR., Jones, CS., Lockyer, AE., Spinks, J. & Rollinson, D. Molluscs, molecules and man: Towards new perspectives in Host-parasite interactions and future control strategies, Other contribution, 2003
  • Holland, JW., Gould, CRW., Jones, CS., Noble, LR. & Secombes, CJ. The expression of immune-regulatory genes in rainbow trout, Oncorhynchus mykiss, during a natural outbreak of proliferative kidney disease (PKD), Article, 2003, Parasitology, 126, ppS95 - 102, ISSN/ISBN: 0031-1820
  • Holland, JW., Gould, CRW., Jones, CS., Noble, LR. & Secombes, CJ. The expression of immune-regulatory genes in rainbow trout, Oncorhynchus mykiss, during a natural outbreak of proliferative kidney disease (PKD), Article, 2003, Parasitology, 126, ppS95 - 102, ISSN/ISBN: 1469-8161
  • Martin, AP., Pardini, AT., Noble, LR. & Jones, CS. Conservation of a dinucleotide simple sequence repeat locus in sharks, Article, 2002, Molecular Phylogenetics and Evolution, 23, 2, pp205 - 213, ISSN/ISBN: 1055-7903
  • Jones, CS., Lockyer, AE., Verspoor, E., Secombes, CJ. & Noble, LR. Towards selective breeding of Atlantic salmon for sea louse resistance: approaches to identify trait markers, Article, 2002, Pest Management Science, 58, pp559 - 568, ISSN/ISBN: 1526-498X
  • Lockyer, AE., Jones, CS., Noble, LR., Verspoor, E., Holland, JW. & Secombes, CJ. Isolation and characterisation of a putative interleukin 13 receptor a2 sequence from rainbow trout (Oncorhynchus mykiss), Article, 2001, Fish & Shellfish Immunology, 11, pp541 - 546, ISSN/ISBN: 1050-4648
  • Jones, CS., Lockyer, AE., Rollinson, D. & Noble, LR. Molecular approaches in the study of Biomphalaria glabrata - Schistosoma mansoni interactions: linkage analysis and gene expression profiling, Article, 2001, Parasitology, 123, ppS181 - S196, ISSN/ISBN: 0031-1820
  • Jones, CS., Lockyer, AE., Rollinson, D. & Noble, LR. Molecular approaches in the study of Biomphalaria glabrata - Schistosoma mansoni interactions: linkage analysis and gene expression profiling, Article, 2001, Parasitology, 123, ppS181 - S196, ISSN/ISBN: 1469-8161
  • Jones, CS., Rollinson, D., Mimpfoundi, R., Ouma, J. & Noble, LR. Molecular evolution of freshwater snail intermediate hosts within the Bulinus forskalii group, Article, 2001, Parasitology, 123, ppS277 - S292, ISSN/ISBN: 0031-1820
  • Jones, CS., Rollinson, D., Mimpfoundi, R., Ouma, J. & Noble, LR. Molecular evolution of freshwater snail intermediate hosts within the Bulinus forskalii group, Article, 2001, Parasitology, 123, ppS277 - S292, ISSN/ISBN: 1469-8161
  • Gow, J., Noble, LR., Rollinson, D. & Jones, CS. Polymorphic microsatellites in the African freshwater snail, Bulinus forskalii (Gastropoda, Pulmonata), Article, 2001, Molecular Ecology Notes, 1, pp237 - 241, ISSN/ISBN: 1471-8278
  • Pardini, AT., Jones, CS., Noble, LR., Kreiser, B., Malcolm, H., Bruce, BD., Stevens, JD., Cliff, G., Scholl, MC., Francis, M., Duffy, CAJ. & Martin, AP. Sex-biased dispersal of great white sharks, Article, 2001, Nature, 412, pp139 - 140, ISSN/ISBN: 0028-0836
  • Webster, JP., Davies, CM., Ndamba, J., Jones, CS., Noble, LR. & Woolhouse, MM. Spatio-temporal population genetics of Biomphalaria pfeifferi in the Zimbabwean Highveld using RAPD markers, Article, 2001, American Journal of Tropical Medicine and Hygiene, 95, pp515 - 527, ISSN/ISBN: 0002-9637
  • Campbell, G., Jones, CS., Lockyer, AE., Hughes, S., Brown, D., Noble, LR. & Rollinson, D. Molecular evidence supports an African affinity of the Neotropical freshwater gastropod, Biomphalaria glabrata, Say 1818, an intermediate host for Schistosoma mansoni, Article, 2000, Proceedings of the Royal Society of London. B, Biological Sciences, 267, pp2351 - 2358, ISSN/ISBN: 0962-8452
  • Rollinson, D., Stothard, JR., Jones, CS., Lockyer, AE., de Souza, CP. & Noble, LR. Molecular characterisation of intermediate snail hosts and the search for resistance genes, Article, 1998, Memorias do Instituto Oswaldo Cruz, 93, pp111 - 116, ISSN/ISBN: 0074-0276
  • Jones, CS., Noble, LR., Lockyer, AE., Brown, DS. & Rollinson, D. Species-specific primers discriminate schistosome intermediate hosts: unambiguous PCR diagnosis of Bulinus forskalii group taxa (Gastropoda: Planorbidae), Article, 1997, Molecular Ecology, 6, 9, pp843 - 849, ISSN/ISBN: 0962-1083
  • Noble, LR. & Jones, CS. A molecular and ecological investigation of the large arionid slugs of North-West Europe: The potential for new pests, Chapter, 1996, Ecology of Agricultural Pests, pp93 - 131
  • Bishop, JDD., Jones, CS. & Noble, LR. Female control of paternity in the internally fertilizing compound ascidian Diplosoma listerianum .2. Investigation of male mating success using RAPD markers, Article, 1996, Proceedings of the Royal Society of London. B, Biological Sciences, 263, 1369, pp401 - 407, ISSN/ISBN: 0962-8452
  • Rollinson, D., Jones, CS. & Noble, LR. New approaches to the identification of medically important freshwater snails associated with irrigated agriculture in Africa, Article, 1996, SLUGS, 66 - 312, ISSN/ISBN: 0306-3941
  • Vernon, JG., Okamura, B., Jones, CS. & Noble, LR. Temporal patterns of clonality and parasitism in a population of freshwater bryozoans, Article, 1996, Proceedings of the Royal Society of London. B, Biological Sciences, 263, 1375, pp1313 - 1318, ISSN/ISBN: 0962-8452
  • Jones, CS., Noble, LR., JONES, JS., TEGELSTROM, H., TRIGGS, GS. & BERRY, RJ. DIFFERENTIAL MALE GENETIC SUCCESS DETERMINES GENE FLOW IN AN EXPERIMENTALLY MANIPULATED MOUSE-POPULATION, Article, 1995, Proceedings of the Royal Society of London. B, Biological Sciences, 260, 1359, pp251 - 256, ISSN/ISBN: 0962-8452
  • VERNON, JG., Jones, CS. & Noble, LR. RANDOM AMPLIFIED POLYMORPHIC DNA (RAPD) MARKERS REVEAL CROSS-FERTILIZATION IN BIOMPHALARIA-GLABRATA (PULMONATA, BASOMMATOPHORA), Article, 1995, Journal of Molluscan Studies, 61, pp455 - 465, ISSN/ISBN: 0260-1230
  • Jones, CS., OKAMURA, B. & Noble, LR. PARENT AND LARVAL RAPD FINGERPRINTS REVEAL OUTCROSSING IN FRESH-WATER BRYOZOANS, Article, 1994, Molecular Ecology, 3, 3, pp193 - 199, ISSN/ISBN: 0962-1083
  • OKAMURA, B., Jones, CS. & Noble, LR. RANDOMLY AMPLIFIED POLYMORPHIC DNA ANALYSIS OF CLONAL POPULATION-STRUCTURE AND GEOGRAPHIC-VARIATION IN A FRESH-WATER BRYOZOAN, Article, 1993, Proceedings of the Royal Society of London. B, Biological Sciences, 253, 1337, pp147 - 154, ISSN/ISBN: 0962-8452

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