Mr ANDREW ELDERS

Mr ANDREW ELDERS The University of Aberdeen School of Medicine & Dentistry Mr ANDREW ELDERS Research Fellow work +44 (0)1224 438158

Statistician

Mr ANDREW ELDERS

Personal Details

Telephone: +44 (0)1224 438158
Email: andrew.elders@abdn.ac.uk
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Biography

Andrew Elders joined the Unit in November 2009 as a research fellow in medical statistics.  He studied mathematics and economics at the University of St Andrews and worked at the Scottish Office in Edinburgh after graduating in 1995.  In February 2001, he moved to Perth, Australia and worked as an analyst for Gee-Woolhouse before returning to the UK to join the Information and Services Division (ISD) of NHS National Services Scotland in September 2002.  Andrew took a 2-year secondment to NHS Fife in 2006 as a senior statistician in the public health department before moving to the Health Intelligence Unit in NHS Lothian in 2008.  He graduated with an MSc in Applied Statistics from Napier University in 2007.  As a member of the statistics team in HSRU, Andrew mainly works on the design and analysis of clinical trials and conducts meta-analyses for systematic reviews.


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Research Interests

Research interests include methodologies for randomised control trials, medical record linkage, quality improvement and analysis of complex sample survey data.


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Current Research

  • FOCCUS: Pragmatic multi-centre randomised controlled trial of routine postoperative ICU care and / or pre-operative fluid loading in high-risk surgical patients undergoing major elective and urgent surgery.
  • eTHoS: Pragmatic multicentre randomised controlled trial comparing stapled haemorrhoidopexy to traditional excisional surgery for haemorrhoidal disease.
  • CLaSS: Randomised controlled trial comparing foam sclerotherapy, alone or in combination with endovenous laser therapy, with conventional surgery as a treatment for varicose veins.
  • PROSPECT: Clinical and cost-effectiveness of surgical options for the management of anterior and/or posterior vaginal wall prolapse:  two randomised controlled trials within a Comprehensive Cohort Study. 
  • ProLong: The relationship of pregnancy and delivery with incontinence and prolapse.
  • TRiaDS: Translation research in a dental setting.
  • IQuaD: Improving quality in dentistry - randomised controlled trial.
  • Surveillance for Ocular Hypertension: Systematic review of the reliability and agreement between alternative tonometers for ascertaining and monitoring ocular hypertension.
  • Indirect comparison of relative effectiveness of ranibizumab and bevacizumab in diabetic macular oedema.
  • Network meta-analysis of insulin treatments for Type II diabetes.
  • Appraisal of denosumab for the treatment of bone metastases from solid tumours and multiple myeloma.
  • Appraisal of pazopanib for the first-line treatment of patients with advanced renal cell carcinoma.
  • Study of the effects on short and long term outcomes of the treatment of severe sepsis with activated protein C.

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Qualifications

  •  MSc Applied Statistics, Edinburgh Napier University
  •  BSc Mathematics and Economics, University of St Andrews

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Selected Publications

Payne RA, Oliver JJ, Bain M, Elders A, Bateman DN (2009). Patterns and predictors of re-admission to hospital with self-poisoning in Scotland. Public Health, 123(2), 134-137.

O'Regan B, Bharadwaj G, Elders A (2008). Techniques for dissection of the facial nerve in benign parotid surgery, a cross specialty survey of oral and maxillofacial and ear nose and throat surgeons in the UK. The British Journal of Oral & Maxillofacial Surgery, 46(7), 564-566.

Mackenzie DG, Elders A, Wild S, Muir R (2008). Thromboprophylaxis for patients at high risk of VTE. Lancet, 371(9628), 1911.

Hanlon P, Lawder R, Elders A, Clark D, Walsh D, Whyte B, Sutton M (2007). An analysis of the link between behavioural, biological and social risk factors and subsequent hospital admission in Scotland. Journal of Public Health, 29(4), 405-412.

Kang JY, Elders A, Majeed A, Maxwell JD, Bardhan KD (2006). Recent trends in hospital admissions and mortality rates for peptic ulcer in Scotland 1982-2002. Alimentary Pharmacology & Therapeutics, 24(1), 65-79.

Nyirenda MY, Clark D, Finlayson AR, Read J, Elders A, Bain M, Fox KAA, Toft AD (2005). Thyroid disease and increased cardiovascular risk. Thyroid, 15(7), 718-724.


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Publications

Contributions to Journals

Articles

  • Hislop, J., Quayyum, Z., Elders, A., Fraser, C., Jenkinson, D., Mowatt, G., Sharma, P., Vale, L. & Petty, R. (2011). 'Clinical effectiveness and cost-effectiveness of imatinib dose escalation for the treatment of unresectable and/or metastatic gastrointestinal stromal tumours that have progressed on treatment at a dose of 400 mg/day: a systematic review and economic evaluation'. Health Technology Assessment, vol 15, no. 25, pp. 1-178.
    [Online] DOI: 10.3310/hta15250
    [Online] AURA: Hislop_2011.pdf
  • Cuthbertson, BH., Campbell, MK., Stott, SA., Elders, A., Hernández, R., Boyers, D., Norrie, J., Kinsella, J., Brittenden, J., Cook, J., Rae, D., Cotton, SC., Alcorn, D., Addison, J., Grant, A. & the FOCCUS study group (2011). 'A pragmatic multi-centre randomised controlled trial of fluid loading in high-risk surgical patients undergoing major elective surgery: the FOCCUS study'. Critical Care, vol 15, no. 6, pp. R296.
    [Online] DOI: 10.1186/cc10592
    [Online] AURA: Cuthbertson_2011.pdf
  • Hislop, JM., Mowatt, G., Sharma, P., Fraser, CM., Elders, AS., Jenkinson, DJ., Vale, L. & Petty, RD. (in press). 'Systematic Review of Escalated Imatinib Doses Compared with Sunitinib or Best Supportive Care, for the Treatment of People with Unresectable/Metastatic Gastrointestinal Stromal Tumours Whose Disease has Progressed on the Standard Imatinib Dose'. Journal of Gastrointestinal CAncer.
    [Online] DOI: 10.1007/s12029-011-9325-6

Books and Reports

Commissioned Reports

  • Cuthbertson, B., Campbell, MK., Stott, S., Vale, LD., Norrie, JDT., Kinsella, J., Cook, JA., Brittenden, J., Grant, AM., Alcorn, D., Serpell, M., McColl, S., Rae, D., Shepherd, K., Addison, J., McPherson, GC., McDonald, AM., Cotton, SC., Elders, AS., MacLennan, GS., Boyers, D. & Hernández, RA. (2010). 'Pragmatic multi-centre randomised trial of (1) routine postoperative ICU care and/or (2) pre-operative fluid loading in high-risk surgical patients undergoing major elective and urgent surgery'. Chief Scientist Office, Edinburgh, United Kingdom.

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