Clinical Trials
Today’s clinical trial is tomorrow’s clinical practice.


The clinical department is one of the busiest University centres in the UK, being the sole provider of secondary and tertiary level cardiological care to a population of more than 500,000 in Grampian Region and the Northern Isles (Orkney and Shetland). The Cardiology Research Group recruits many patients to a number of multi-centre randomised controlled trials of pharmacological therapy.

Currently, patients with a wide spectrum of cardiovascular disease are involved with the following studies:

ACTIVE – A parallel randomised controlled evaluation of Clopidogrel plus Aspirin, with factorial evaluation of Ibesartan, for the prevention of vascular events in patients with atrial fibrillation.

ARCHIPELAGO - a randomised comparison of a two month regimen of irbesartan versus enalapril on cardiovascular markers in patients with acute coronary syndrome without ST segment elevation

ARISE – A randomised double-blind study evaluating the effects of a new anti-inflammatory agent in reduction of progression of atherosclerosis and cardiac events.

FAMI A study of the environmental, inflammatory and genetic causes , and of the gene-environment interactions which cause MI in Italy, China and Scotland.

HAT – Home AED Trial: A multi-centre randomised trial, comparing lay use of an AED (automatic external defibrillator), versus lay activation of standard medical emergency services, for sudden cardiac arrest in patients with a history of anterior wall MI.

MBG - An open-label study to investigate the prognostic usefulness of I-mIBG imaging to investigate patients with NYHA class II or III Heart Failure who will experience an adverse cardiac event.


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