Dr Sharon Mitchell

Dr Sharon Mitchell The University of Aberdeen School of Biological Sciences Research Fellow work +44 (0)1224 273637

Research Fellow

PhD (Aberdeen University 2002)

Personal Details

Telephone: +44 (0)1224 273637
Email: s.e.mitchell@abdn.ac.uk
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Research Interests

Hormonal interactions in the hypothalamus and their involvement in obesity. 


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Current Research

 


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Publications

Contributions to Journals

Articles

  • Zhang, L-N, Gamo, Y., Sinclair, R., Mitchell, SE., Morgan, DG., Clapham, JC. & Speakman, JR. (2012). 'Effects of Chronic Oral Rimonabant Administration on Energy Budgets of Diet-Induced Obese C57BL/6 Mice'. Obesity, vol 20, no. 5, pp. 954-962.
    [Online] DOI: 10.1038/oby.2011.357
  • Zhang, L-N, Mitchell, SE., Hambly, C., Morgan, DG., Clapham, JC. & Speakman, JR. (2012). 'Physiological and behavioral responses to intermittent starvation in C57BL/6J mice'. Physiology and Behavior, vol 105, no. 2, pp. 376-387.
    [Online] DOI: 10.1016/j.physbeh.2011.08.035
  • Speakman, JR. & Mitchell, SE. (2011). 'Caloric Restriction'. Molecular Aspects of Medicine, vol 32, no. 3, pp. 159-221.
    [Online] DOI: 10.1016/j.mam.2011.07.001
  • Robinson, JJ., McKelvey, WAC., King, ME., Mitchell, SE., Mylne, MJA., McEvoy, TG., Dingwall, WS. & Williams, L. (2011). 'Traversing the ovine cervix: a challenge for cryopreserved semen and creative science'. Animal, vol 5, no. 11, pp. 1791-1804.
    [Online] DOI: 10.1017/S1751731111000978
  • Hempenstall, S., Picchio, L., Mitchell, SE., Speakman, JR. & Selman, C. (2010). 'The impact of acute caloric restriction on the metabolic phenotype in male C57BL/6 and DBA/2 mice'. Mechanisms of Ageing and Development, vol 131, no. 2, pp. 111-118.
    [Online] DOI: 10.1016/j.mad.2009.12.008
  • Mitchell, SE., Nogueiras, R., Morris, A., Tovar, S., Grant, C., Cruickshank, M., Rayner, DV., Dieguez, C. & Williams, L. (2009). 'Leptin receptor gene expression and number in the brain are regulated by leptin level and nutritional status'. Journal of Physiology, vol 587, no. 14, pp. 3573-3585.
    [Online] DOI: 10.1113/jphysiol.2009.173328
  • Sneddon, AA., Rayner, DV., Mitchell, SE., Bashir, S., Ha, J-H, Wahle, KWJ., Morris, A. & Williams, L. (2009). 'Dietary supplementation with conjugated linoleic acid plus n-3 polyunsatturated fatty acid increases food intake and brown adipose tissue in rats'. Nutrients, vol 1, no. 2, pp. 178-196.
  • Speakman, JR., Hambly, C., Mitchell, SE. & Król, E. (2008). 'The contribution of animal models to the study of obesity'. Laboratory Animals, vol 42, no. 4, pp. 413-432.
    [Online] DOI: 10.1258/la.2007.006067
  • Speakman, J., Hambly, C., Mitchell, S. & Król, E. (2007). 'Animal models of obesity'. Obesity Reviews, vol 8, no. Suppl 1, pp. 55-61.
    [Online] DOI: 10.1111/j.1467-789X.2007.00319.x
  • Nogueiras, R., Pfluger, P., Tovar, S., Arnold, M., Mitchell, SE., Morris, A., Perez-Tilve, D., Vázquez, MJ., Wiedmer, P., Castañeda, TR., DiMarchi, R., Tschöp, M., Schurmann, A., Joost, H-G, Williams, L., Langhans, W. & Diéguez, C. (2007). 'Effects of Obestatin on Energy Balance and Growth Hormone Secretion in Rodents'. Endocrinology, vol 148, no. 1, pp. 21-26.
    [Online] DOI: 10.1210/en.2006-0915
  • Mitchell, SE., Nogueiras, R., Rance, K., Rayner, DV., Wood, S., Dieguez, C. & Williams, L. (2006). 'Circulating hormones and hypothalamic, energy balance'. Journal of Endocrinology, vol 190, no. 3, pp. 571-579.
    [Online] DOI: 10.1677/joe.1.06576
  • Nogueiras, R., Tovar, S., Mitchell, SE., Barrett, P., Rayner, DV., Dieguez, C. & Williams, L. (2006). 'Negative energy balance and leptin regulate neuromedin-U expression in the rat pars tuberalis'. Journal of Endocrinology, vol 190, no. 2, pp. 545-553.
    [Online] DOI: 10.1677/joe.1.06577
  • Mitchell, SE., Robinson, JJ., King, ME. & Williams, L. (2005). 'Proteinase-activated receptors in ovine cervical function'. Reproduction, Fertility, Development, vol 17, no. 7, pp. 693-699.
    [Online] DOI: 10.1071/RD05032
  • Kola, B., Hubina, E., Tucci, SA., Kirkham, TC., Garcia, EA., Mitchell, SE., Williams, L., Hawley, SA., Hardie, DG., Grossman, AB. & Korbonits, M. (2005). 'Cannabinoids and ghrelin have both central and peripheral metabolic and cardiac effects via AMP-activated protein kinase'. Journal of Biological Chemistry, vol 280, no. 26, pp. 25196-25201.
    [Online] DOI: 10.1074/jbc.C500175200
  • Nogueiras, R., Tovar, S., Mitchell, SE., Rayner, DV., Archer, ZA., Dieguez, C. & Williams, L. (2004). 'Regulation of growth hormone secretagogue receptor gene expression in the arcuate nuclei of the rat by leptin and ghrelin'. Diabetes, vol 53, no. 10, pp. 2552-2558.
    [Online] DOI: 10.2337/diabetes.53.10.2552
  • Mitchell, SE., Robinson, JJ., King, ME., McKelvey, WAC. & Williams, L. (2002). 'Interleukin 8 in the cervix of non-pregnant ewes'. Reproduction, vol 124, no. 3, pp. 409-416.
  • Steinhoff, M., Vergnolle, N., Young, SH., Tognetto, M., Amadesi, S., Ennes, HS., Trevisani, M., Hollenberg, MD., Wallace, JL., Caughey, GH., Mitchell, SE., Williams, L., Geppetti, P., Mayer, EA. & Bunnett, NW. (2000). 'Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism'. Nature Medicine, vol 6, no. 2, pp. 151-158.
    [Online] DOI: 10.1038/72247
  • Brogan, RS., Mitchell, SE., Trayhurn, P. & Smith, MS. (1999). 'Suppression of leptin during lactation: contribution of the suckling stimulus versus milk production'. Endocrinology, vol 140, no. 6, pp. 2621-7.
  • Mitchell, SE., Rees, W., Hardie, MJ., Hoggard, N., Tadayyon, M., Arch, JR. & Trayhurn, P. (1997). 'ob gene expression and secretion of leptin following differentiation of rat preadipocytes to adipocytes in primary culture'. Biochemical and Biophysical Research Communications, vol 230, no. 2, pp. 360-364.
    [Online] DOI: 10.1006/bbrc.1996.5964

Abstracts

  • Hambly, C., Mitchell, SE., Speakman, JR. & Williams, L. (2007). 'The Lou/C rat is proportionally smaller than the Wistar and not anorexic or hyperactive as previously reported'. International Journal of Obesity, vol 31, no. S1, T2:PO.28, pp. S84-S84.
    [Online] DOI: 10.1038/sj.ijo.0803597

Chapters in Books, Reports and Conference Proceedings

Conference Proceedings

  • Trayhurn, P., Hoggard, N., Mitchell, SE. & Rayner, DV. (1998). 'Nutritional and hormonal regulation of the leptin system'. in Proceedings of the 16th International Congress of Nutrition - Nutrition Montreal 97: From nutritional science to nutrition practice for better global health. CANADIAN FEDERATION BIOLOGICALSOCIETIES, Ottawa, Canada, pp. 121-123.

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