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Dr Sharon Mitchell The University of Aberdeen School of Biological Sciences Research Fellow work +44 (0)1224 273637 pref s.e.mitchell@abdn.ac.uk

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Research Interests

Hormonal interactions in the hypothalamus and their involvement in obesity. 

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Current Research

 

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Selected Publications

• Mitchell SE, Nogueiras R, Morris A, Tovar S, Grant C, Cruickshank M, Rayner DV, Dieguez C and Williams LM.(In Prep) Regulation of leptin receptor gene expression and [125I]leptin binding sites in the mouse brain by nutritional status and leptin.
• Mitchell SE, Nogueiras R, Rance K, Rayner DV, Wood S, Dieguez C and Williams LM.(In Press)Circulating hormones and hypothalamic energy balance regulatory gene expression in theLou/C and Wistar rat. J. Endocrinology
• Mitchell SE, Robinson JJ, King ME and Williams LM (2005) Proteinase-activated receptors in ovine cervical function. Reproduction, Fertility and Development. 17: 693-699
• Kola B, Hubina E, Tucci SA, Kirkham TC, Garcia EA, Mitchell SE, Williams LM, Hawley SA, Hardie G, Grossman B and Korbonits M (2005) Cannabinoids and ghrelin have both central and peripheral metabolic and cardiac effects via AMP-activated protein kinase. Journal of Biological Chemistry 280: 25196-25201
• Nogueiras R, Tovar S, Mitchell SE, Rayner DV, Archer ZA, Dieguez C and Williams LM (2004) Regulation of growth hormone secretagogue receptor gene expression in the arcuate nuclei of the rat by leptin and ghrelin. Diabetes 53: 2552-2558
• Mitchell SE, Robinson JJ, King ME, McKelvey WAC, Williams LM 2002) Interleukin 8 in the cervix of non-pregnant ewes. Reproduction 124: 409-416.
• Steinhoff M, Vergonelle N, Young S, Ennes H, Hollenberg MD, Wallace JL, Caughey GH, Mitchell SE, Williams LM, Gepetti P, Mayer EA and Bunnett NW (2000) Agonists of protease-activated receptor 2 induce inflammation by a neurogenic mechanism. Nature Medicine 6: 151-158.
• Robinson JJ, Williams LM, Mitchell SE, Mylne MJ, McKelvey WAC (1999) Towards improved reproductive technologies for sheep. Animal and Food Science Research Report, Scottish Agricultural College 2-5.
• Brogan RS, Mitchell SE, Trayhurn P, Smith MS (1999) Suppression of leptin during lactation: Contribution of the suckling stimulus versus milk production. Endocrinology (6) 2621-2627.
• Trayhurn P, Hoggard H, Mitchell SE, and Rayner DV. (1997) Nutritional and hormonal regulation of the leptin system. Proceedings of the 16th International Congress on Nutrition – Montreal - From Nutritional Science to Nutrition Practice for Better Global Health. Fitzpatrick DW, Anderson JE and L’Abbe M Eds. Canadian Federation Biological Societies, Ottawa.
• Mitchell SE, Rees WD, Hardie LJ, Hoggard N, Tadayyon M, Arch JRS, and Trayhurn P (1997) ob gene expression in and secretion of leptin following differentiation of rat preadipocytes to adipocytes in primary culture. Biochemical and Biophysical Research Communications 230: 60-364.

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