Professor DAVID SALT

Professor DAVID SALT The University of Aberdeen School of Biological Sciences Professor DAVID SALT 6th Century Chair work +44 (0)1224 272696 http://www.ionomicshub.org pref University of Aberdeen Institute of Biological and Environmental Sciences Cruickshank Building St Machar Drive, Aberdeen, Scotland AB24 3UU, United Kingdom

6th Century Chair

Professor DAVID SALT

Personal Details

Telephone: +44 (0)1224 272696
Email: david.salt@abdn.ac.uk
Personal website: http://www.ionomicshub.org
Address: University of Aberdeen
Institute of Biological and Environmental Sciences
Cruickshank Building
St Machar Drive, Aberdeen, Scotland
AB24 3UU, United Kingdom
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Ionomics HUB http://www.ionomicshub.org

Literature Cloud http://www.ionomicshub.org/litcloud/

Ionomic Atlas http://www.ionomicshub.org/ionomicsatlas/


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Biography

EDUCATION

1981 - 1984       B.Sc. (Hons)  Biochemistry, 1st class with distinction, University College North Wales, Bangor, U.K.      

1984 - 1985       M.Sc.  Computer Studies, Hallam University, Sheffield, U.K.

1985 - 1988       Ph.D.  Thesis Title: Copper-binding peptides of Mimulus guttatus, Supervisor: DA Thurman, Liverpool University, Liverpool, U.K.

POSTDOCTORAL TRAINING

1988 - 1990       Team Leader, Centre for Biochemical Engineering, University College London,    London, U.K.

1990 - 1992       Postdoctoral Scholar, with GJ Wagner, Department of Agronomy, University of Kentucky, Lexington, KY, USA

1992 - 1993       Research Associate, with WE Rauser, Botany Department, Guelph University, Guelph, Ontario, Canada.

EMPLOYMENT HISTORY

1993 - 1997       Assistant Research Professor, Center for Agricultural Molecular Biology, Rutgers University, New Brunswick, NJ, USA

1995 - 1999       Consultant and member of Science Advisory Board for Phytotech Inc, Monmouth Junction, NJ, USA

1998 - 2000       Assistant Professor of Biochemistry, Department of Chemistry, Northern Arizona University, Flagstaff, AZ, USA.

2000 - 2004       Consultant and member of Science Advisory Board for NuCycle Inc., Monmouth Junction, NJ.

2000 – 2001      Associate Professor of Biochemistry, Dept of Chemistry, Northern Arizona University, Flagstaff, AZ, USA.

2001 – 2005      Associate Professor, Dept Horticulture and Landscape Architecture, Purdue University, West Lafayette, IN, USA.

2004 – 2007      Scientific Director for Genomic Research and Technology, Bindley Bioscience Center, Discovery Park, Purdue University, West Lafayette, IN, USA.

2005 – 2011      Professor, Dept Horticulture and Landscape Architecture, Purdue University, West Lafayette, IN

2011 – present  Professor and Sixth Century Chair, School of Biological Sciences, University of Aberdeen, Aberdeen, UK.

HONORS AND AWARDS

  • Fellow of the American Association for the Advancement of Science (AAAS), 2011.
  • Fellow of the Royal Society of Chemistry (FRSC), 2010.
  • The Purdue University Herbert Newby McCoy Award winner, 2010.
  • Critiques and Awards Program, Gold Award for Genomics Explorer exhibit, Association for Communication Excellence, 2010.
  • First prize Interactive Media Award, Science and Engineering Visualization Challenge, NSF/AAAS, 2008 (Science 321: 1767-1775 (Sept 2008) for the Genomics Digital Lab (GDL).
  • World Summit Awards e-Science & Technology winner for the Genomics Digital Lab (GDL), 2009 http://www.wsis-award.org/winners/winners.wbp
  • Purdue University Faculty Scholar 2003 – 2008
  • Nominated by Nature Biotechnology (March 2006) as one of the “thought leaders and technology pioneers” in biotechnology in the past 10 years (Nature Biotech 24: 291).

PhD STUDENTS, POSTDOCTORAL RESEARCHERS AND TECHNICAL STAFF

Ph.D. Students

  • John Freeman, (Purdue Univeristy 2001 – graduated 2004)
  • Jeff Gustin (Purdue University 2002 – graduated 2007).
  • Tommy Sors (Purdue University 2003 – graduated 2008)
  • Gun-Nam Na (Purdue University 2003 – graduated 2009)
  • Prashant Hosmani (Purdue University 2007 – graduated 2012)
  • Jessica Brazelton (Purdue University 2008 – graduated 2012)
  • Macarena Maria Silva Guzman (Purdue University 2010 – present)
  • Monika Ewa Mierzwinska (Univeristy of Aberdeen 2012 – present)

 M.Sc Students

  • Pam Motley, (Northern Arizona University 1998 – graduated 2000)
  • Matt Mandreat (Purdue University 2008 – graduated 2011)

 Postdoctoral Research Fellows

  • Dr. Xianghe Yan (Rutgers University 1996 - 1997)
  • Dr. Lakhar Sreedhar (Rutgers University 1996 - 1997)
  • Dr. Ute Krämer (Rutgers University 1996 - 1997)
  • Dr. Mike Persans (Northern Arizona University 1998 - 2002)
  • Dr Dennis Brunk (Purdue University 2001 – 2003)
  • Dr Bakhtiyor Yakubov (Purdue University 2001 – 2007)
  • Dr Mehrzad Mahmoudian (Purdue University 2001 – 2003)
  • Dr Wendy Peer (Purdue University 2001 – 2003)
  • Dr Donggiun Kim (Purdue University 2002 – 2005)
  • Dr Muthukumar Balasubramaniam (Purdue University 2003 – 2009)
  • Dr Ana Rus (Purdue University 2003 – 2006)
  • Dr Danielle Ellis (Purdue University 2001 – 2006)
  • Dr. Ivan Baxter (Purdue University 2004 – 2009)
  • Dr. Hyeong Cheol Park (Purdue University 2005 – 2008)
  • Dr. John Danku (Purdue University 2006 – 2011)
  • Dr. Monica Borghi (Purdue University 2007 – 2010)
  • Dr. Daiyin Chao (Purdue University/Univeristy of Aberdeen 2007 – present)
  • Dr. Xinyuan Huang (Purdue University/University of Aberdeen 2010 - present)
  • Dr. Takehiro Kamiya (Universitry of Aberdeen 2011 – present).

Technical Research Support Staff

  • Jean-Marc Patnoe (Northern Arizona University 1998 - 1999)
  • Teresa Thompson (Purdue University 2004 - 2011)
  • Brett Lahner (Purdue University 2000 – 2011)
  • Elena Yakubov (Purdue University 2004 – 2011)
  • Marina Tikhonova (Purdue University 2007 – 2009)
  • Dr. Daniel Lou-Hing (University of Aberdeen 2012 – present)
  • Dr. John Danku, Ionomics technologist (University of Aberdeen 2011 – present)

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Research Interests

Professor Salt’s long term research interest is to understand the function of the genes and gene networks that regulate the plant ionome [defined as the elemental composition of an organism, tissue or cell], along with the evolutionary forces that shape this regulation. It was Professor Salt’s pioneering work (Lahner et al., 2003), along with his collaborators, that led to the new research paradigm of ionomics (reviewed in Salt et al., 2008). This ionomics approach was featured on the cover of Nature Biotechnology, was the subject of a “News and Views” in Nature Biotechnology (Rea, 2003), and was reviewed in Trends in Biotechnology, where the approach was described as “an impressive incorporation of plant genetics, analytical chemistry and statistical analysis.”

To encourage a diverse group of researchers to participate in ionomics, Professor Salt has developed a unique online web-based community portal called the ionomicsHUB (www.ionomicshub.org). The ionomicsHUB focuses on both workflow control for high-throughput data collection (Baxter et al., 2007), and delivery of ionomic data to the community. New funding is now allowing additional new tools and resources to be added to the iHUB, as well as supporting community meetings and workshops to further develop the community and refine the iHUB.

Professor Salt is committed to engagement with the public through informal science education. He has developed a 2,000 sq ft informal science exhibit on genomics called Genomics Explorer (http://www.genomicsexplorer.com/) which has been displayed at the Indiana State Fair, Owensboro Museum of Science and History, and the Danville Science Center.  This exhibit won Gold at the Critiques and Awards Program, Association for Communication Excellence, 2010. Professor Salt has also developed the award winning science-based interactive game the Genomics Digital Lab (http://www.aspb.org/education/GDLProject.CFM). This game has won first prize in 2008 in the Interactive Media Award, Science and Engineering Visualization Challenge, and at the World Summit Awards e-Science & Technology, 2009.

Professor Salt has developed a novel functional genomics approach to study the ionome, combining high-throughput elemental analysis with bioinformatics, genetics and genomics. Using this approach he has published a series of high impact papers (Rus et al. 2006, Baxter et al., 2008ab, Baxter et al., 2009, Morrissey et al., 2009, Atwell et al., 2010; Baxter et al., 2010) that not only provide new biological insight into the mechanisms regulating the plant ionome, but also validate this type of approach. Professor Salt’s research using this approach has also started to reveal the molecular basis of plant adaptation to the environment. For example, a recent publication by Professor Salt (Baxter et al., 2010) provides strong evidence that selection is acting on the Na-transporter HKT1 to adapt local populations of A. thaliana in Europe to saline environments, and this paper was described by one reviewer as “This paper should stand as an example to other researchers hoping to thoroughly describe mechanisms of adaptation.”

GX figure

Fig 2. Genomics Explorer exhibit. (A) Overview of exhibit. (B) O2 interactive (C) Foreground Microscope, background DNA Dinner. (D) Walk Through Cell. (E) Genomics Digital Laboratory game. (F) Genomics Puzzle Pieces. (G) Visitor collecting one of the stamps to solve the “Genomics Puzzle”. For more details see http://www.genomicsexplorer.com/

Professor Salt has been a pioneer in using DNA microarrays to map the physical location of mutations. Two of Professor Salt’s papers were recently profiled in a review on root genomics by Benfey et al., (2010), highlighting the success of this approach. Professor Salt has also been an early pioneer in successfully applying genome-wide association analysis (GWA) to identify loci involved in regulating the ionome (Atwell et al., 2010; Baxter et al., 2010). Continuing to adopt new technologies to enhance his research approach, Professor Salt is currently applying short read resequencing technologies for the identification of causal DNA polymorphisms in A. thaliana ionomic mutants.

Professor Salt has also gone on to extend ionomics into yeast, completing a screen of all 12,000 strains in the full-genome knockout and overexpression collections. This unique data set is now being leveraged to better understand the regulation of the ionome in other species including A. thaliana and rice. Through collaborations Professor Salt is also extending the ionomics concept into C. elegans and mouse.

To encourage a diverse group of researchers to participate in ionomics, Professor Salt has developed a unique online web-based community portal called the ionomicsHUB (www.ionomicshub.org). The ionomicsHUB focuses on both workflow control for high-throughput data collection (Baxter et al., 2007), and delivery of ionomic data to the community. New funding is now allowing additional new tools and resources to be added to the iHUB (Fig 3), as well as supporting community meetings and workshops to further develop the community and refine the iHUB.


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Current Research

Professor Salt has developed a novel functional genomics approach to study the ionome, combining high-throughput elemental analysis with bioinformatics, genetics and genomics. Using this approach he has published a series of high impact papers (e.g. Rus et al. 2006, Baxter et al., 2008ab, Baxter et al., 2009, Morrissey et al., 2009, Atwell et al., 2010; Baxter et al., 2010, Tian et al., 2010; Choa et al., 2011; Borghi et al., 2011) that not only provide new biological insight into the mechanisms regulating the plant ionome, but also validate this type of approach. Professor Salt’s research using this approach has also started to reveal the molecular basis of plant adaptation to the environment. For example, a recent publication by Professor Salt (Baxter et al., 2010) provides strong evidence that selection is acting on the Na-transporter HKT1 to adapt local populations of A. thaliana in Europe to saline environments, and this paper was described by one reviewer as “This paper should stand as an example to other researchers hoping to thoroughly describe mechanisms of adaptation.”

Professor Salt has been a pioneer in using DNA microarrays to map the physical location of mutations. Two of Professor Salt’s papers were recently profiled in a review on root genomics by Benfey et al., (2010), highlighting the success of this approach. Professor Salt has also been an early pioneer in successfully applying genome-wide association (GWA) mapping to identify loci involved in regulating the ionome (Atwell et al., 2010; Baxter et al., 2010). Continuing to adopt new technologies to enhance his research approach, Professor Salt is currently applying short read next generation resequencing technologies for the identification of causal DNA polymorphisms in A. thaliana ionomic mutants, and natural accessions of A. thaliana and rice.

Professor Salt has also been applying these ionomic techniques for the identification of genes that control the mineral nutrient and trace element content of rice grain. This approach entails measuring the rice grain ionome in over 1,700 natural accessions of rice grown in the field. From this information accessions have been selected to develop over 25 mapping populations which Professor Salt is now using to identify the genes that control the rice grain ionome.


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Research Grants

FUNDED RESEARCH GRANTS

Ongoing Research projects

  • Ionome to Genome: Mapping the Gene Networks Controlling Nutrient Content in Rice grain, US National Science Foundation, Plant Genome Research Program (PI David E Salt, CoPI’s Mary Lou Guerinot, Shannon Pinson), 09/09/2007 – 07/31/2014, Purdue University $6,873,734
  • Cyberinfrastructure to enabled plant adaptation research, NSF supported iPlant Collaborative (PI David E Salt), 01/01/2011 – 31/3/2012, Purdue University $68,005
  • The genetic basis and adaptive significance of natural ionomic variation, FP7 Marie Curie Career Integration Grant (CIG) (PI David E Salt), 11/08/2011 – 10/08/2015, University of Aberdeen €100,000
  • The genetic basis of natural ionomic variation, US National Institutes of Health (PIs David E Salt and Mary Lou Guerinot), 04/01/2011 – 03/31/2015, University of Aberdeen £296,646.
  • The iHUB: A collaborative international network for ionomics, US National Science Foundation (PI David E Salt, CoPI Mourad Ouzzani), 06/01/2010 – 05/31/2014, Purdue University $527,339
  • US-Brazilian Rice Ionomics Collaborative (USBRIC), US National Science Foundation, Developing Country Collaborations in Plant Genome Research (DCC-PGR) (PI David E Salt), 08/01/2008 – 07/31/2012, Purdue University $95,500
  • Mechanisms underlying arsenic tolerance and hyperaccumulation in the fern Pteris vittata, US National Science Foundation (PI Jody Banks, CoPI David E Salt), 02/15/2009 – 01/31/2012, Purdue University $400,000

Completed Research Support

  • Tools to Facilitate Collaboration within the Virtual Ionomics Network at ionomicshub.org to Foster Ionomic Discovery, Purdue University Cyber Center (PI David E Salt, CoPI Ivan Baxter), 01/01/2009 – 12/31/2009, $49,000
  • The Genetic basis of natural ionomic variation, National Institutes of Health (PI David E Salt, CoPI Mary Lou Guerinot, Magnus Nordborg), 01/08/2010 – 12/31/2010, $135,175
  • Arsenic Uptake, Transport and Accumulation in Plants project #9, National Institutes of Health. This is a Program Project grant lead by PI Joshua Hamilton entitled “Toxic Metals in the Northeast: From Biological to Environmental Implications (Project #9 PI Mary Lou Guerinot, coPI David E Salt), 04/08 – 03/13, $208,690
  • The Genetic basis of natural ionomic variation, National Institutes of Health (PI David Salt, CoPI Mary Lou Guerinot, Magnus Nordborg), 03/31/2007 – 03/30/2010, $1,086,788
  • Acquisition of Metabolic Profiling Instrumentation at Purdue, National Science Foundation, MRI, (PI Clint Chapple, CoPI’s David Rhodes, David Salt, Barry Wanner), 10/01/04 - 09/30/07, Purdue award $839,427.
  • Tools for differential metabolomics, National Institute of Health Road Map, (PI Fred Regnier, CoPI’s Jiri Adamec, Graham Cook, Jo Davisson, John Morgan, Dan Raftery, David Salt, Barry Wanner), 10/01/04 - 09/30/07, Purdue award $4,719,117 (Salt budget $778,107).
  • Ionomics. National Science Foundation, 2010 Project, (Pi Guerinot M-L, CoPI’s Harper J, Salt DE Schroeder J, Ward J), 9/1/2004 to 8/31/2008, Purdue award $1,222,015 (total $3,490,000).
  • Molecular dissection of arsenic hyperaccumulation in the fern Pteris vittata US Department of Energy (PI Banks J, CoPI Salt DE), 9/01/2003 to 8/31/2006, $450,000
  • Center for Phytoremediation Research and Development. Fund for the 21st Century (CoPI  Kathy Banks) 07/01/2003 to 06/30/2007, $2,000,000.
  • Monitoring Phytoremediation Processes Using the Green Fluorescent Protein. Department of Energy, Small Business Technology Transfer Program, Phase II, 9/01/2002 to 8/31/2004, $500,000 Purdue award $350,000.
  • Characterization of potential cesium binding ligands in plant root exudates. Brookhaven National Laboratory, 01/01/2002 to 05/31/2002, $15,315
  • Monitoring Phytoremediation Processes Using the Green Fluorescent Protein. Department of Energy, Small Business Technology Transfer Program, Phase I, 9/01/2001 to 6/30/2002, $99,791.44, Purdue award $56,853.
  • Genome-wide hunt for metal hyperaccumulation genes. National Science Foundation, Integrative Plant Biology, 7/1/2001 to 6/30/2004, $450,000
  • Selenium enriched plant material for chemoprevention. National Institute of Health, Department of Health and Human Services, National Cancer Institute, Small Business Technology Transfer Program, Phase II. 5/1/2001 to 5/2/2003, $399,273 Purdue $169,498
  • Molecular mechanisms of nickel hyperaccumulation in Thlaspi goesingense. National Science Foundation, Integrative Plant Biology, 6/01/2001 to 5/31/2004, $329,807
  • Gene discovery in aid of plant nutrition, human health and environmental remediation. National Science Foundation, Plant Functional Genomics (Pi Guerinot M-L, CoPI’s Schroeder J, Harper J, Eide D, Salt DE), 9/1/2000 to 8/31/2004, Purdue award $689,611 (total $4,414,644).
  • Selenium enriched plant material for chemoprevention, National Institute of Health, Department of Health and Human Services, National Cancer Institute, Small Business Technology Transfer Program, Phase I. 1/1/99 to 12/31/2000, $100,000.
  • Molecular dissection of the cellular mechanisms involved in nickel hyperaccumulation in plants, US Department of Energy, 9/15/96 to 01/31/2000, $495,938.
  • Phytofiltration: A novel approach to water treatment using seedlings, US Department of Agriculture, 12/1/96 to 4/30/2000, $116,664.

FUNDED TEACHING GRANTS

Completed Grants

  • Genomics Revolution Uncloaked American Society of Plant Biologists, Education Foundation 08/01/2005, $30,000
  • Chemistry and genomics-driven drug discovery. The Camille and Henry Dreyfus Foundation, Inc., Special Grant Program in the Chemical Sciences, 01/27/00, $25,199 (CoPI with Dr Paul Torrence and Dr Colleen Kelley).
  • A day in the life of a protein- The green fluoresecent protein as a laboratory teaching aid. National Science Foundation, Course, Curriculum and Laboratory Improvement (CCLI), 09/01/99 to 08/31/2001, $91, 671 (NAU match of $94,524, providing a total of $186, 195).

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Teaching Responsibilities

Northern Arizona University

  • Introductory Chemistry (CHM 151)
  • Fundamental Biochemistry (CHM 360)
  • Biochemistry (CHM 460)
  • Fundamental Biochemistry Laboratory (CHM 360L)

Purdue University

  • Plant Physiology (HORT 301)
  • Planning and Presenting Horticulture Research (HORT 601)

University of Aberdeen

  • Biology for Undergraduates BI1006
  • Biological Topics in Plant and Soil Science BI25P2
  • Plant Environment Interactions PL3504

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External Responsibilities

  • Fellow of the American Association for the Advancement of Science.
  • Fellow of the Royal Society of Chemistry.
  • Member of The American Society of Plant Biologists.
  • Member of the US Department of Energy grants review panel.
  • Member of the US Environmental Protection Agency grants review panel.
  • Member of the United States Department of Agricutlure grants review panel.
  • Member of the US National Science Foundation grant review panel.
  • Editorial Board member, Metallomics 2008 – present.
  • Editorial Board member, Plant and Cell Physiology (PCP), 2011 - 2014.
  • Editorial Board member Molecular Plant, 2012 – present.
  • Editorial Board member, International Journal of Phytorememdiation, 2003 – 2009.
  • Editorial Board member, BMC Plant Biology, 2004 – 2007.
  • Monitoring Editor, Plant Physiology 2005 – 2011.
  • Associate Editor, Brazilian Journal of Plant Physiology, 2007 – present.
  • American Society of Plant Biologists Education Committee member 2003 – 2007.
  • American Society of Plant Biologists Committee on Public Affairs 2007 – 2009.
  • Organizer of iPlant Adapation workshop, 2008.
  • Chair Plant Science Opportunities Team, iPlant (http://www.iplantcollaborative.org/),  2009 – present.
  • Coorganizer iPlant 2010 Conference, Las Vegas, May 2010.
  • Organizer of New Phytologist sponsored workshop ‘Ecological and Evolutionary Genomics of Plant Adaptation’, Aberdeen, June 2012.
  • Member Faculty of 1000 editoral team, 2010 – present.

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Admin Responsibilities

Co-Director of the University of Aberdeen Centre for Genome Enabled Biology and Medicine


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Publications

Contributions to Journals

Articles

  • Danku, JMC., Lahner, B., Yakubova, E. & Salt, DE. (2013). 'Large-scale plant ionomics'. Methods in Molecular Biology, vol 953, pp. 255-276.
    [Online] DOI: 10.1007/978-1-62703-152-3_17
  • Norton, GJ., Pinson, SRM., Alexander, J., Mckay, S., Hansen, H., Duan, G-L, Islam, MR., Islam, S., Stroud, JL., Zhao, F-J, McGrath, SP., Zhu, Y-G, Lahner, B., Yakubova, E., Guerinot, ML., Tarpley, L., Eizenga, GC., Salt, DE., Meharg, AA. & Price, AH. (2012). 'Variation in grain arsenic assessed in a diverse panel of rice (Oryza sativa) grown in multiple sites'. New Phytologist, vol 193, no. 3, pp. 650-664.
    [Online] DOI: 10.1111/j.1469-8137.2011.03983.x
  • Lowry, DB., Sheng, CC., Zhu, Z., Juenger, TE., Lahner, B., Salt, DE. & Willis, JH. (2012). 'Mapping of ionomic traits in Mimulus guttatus reveals Mo and Cd QTLs that colocalize with MOT1 homologues'. PLoS ONE, vol 7, no. 1, e30730.
    [Online] DOI: 10.1371/journal.pone.0030730
  • Baxter, I., Hermans, C., Lahner, B., Yakubova, E., Tikhonova, M., Verbruggen, N., Chao, D. & Salt, DE. (2012). 'Biodiversity of Mineral Nutrient and Trace Element Accumulation in Arabidopsis thaliana'. PloS one, vol 7, no. 4, e35121.
    [Online] DOI: 10.1371/journal.pone.0035121
  • Chao, D-Y, Silva, A., Baxter, I., Huang, YS., Nordborg, M., Danku, J., Lahner, B., Yakubova, E. & Salt, DE. (2012). 'Genome-Wide Association Studies Identify Heavy Metal ATPase3 as the Primary Determinant of Natural Variation in Leaf Cadmium in Arabidopsis thaliana'. PLoS Genetics, vol 8, no. 9, e1002923.
    [Online] DOI: 10.1371/journal.pgen.1002923
  • Liu, W., Schat, H., Bliek, M., Chen, Y., McGrath, SP., George, G., Salt, DE. & Zhao, F-J (2012). 'Knocking Out ACR2 Does Not Affect Arsenic Redox Status in Arabidopsis thaliana: implications for as detoxification and accumulation in plants'. PloS one, vol 7, no. 8, e42408.
    [Online] DOI: 10.1371/journal.pone.0042408
  • Kiani, SP., Trontin, C., Andreatta, M., Simon, M., Robert, T., Salt, DE. & Loudet, O. (2012). 'Allelic Heterogeneity and Trade-Off Shape Natural Variation for Response to Soil Micronutrient'. PLoS Genetics, vol 8, no. 7, e1002814.
    [Online] DOI: 10.1371/journal.pgen.1002814
  • Yu, D., Danku, JM., Baxter, I., Kim, S., Vatamaniuk, OK., Vitek, O., Ouzzani, M. & Salt, DE. (2012). 'High-resolution genome-wide scan of genes, gene-networks and cellular systems impacting the yeast ionome'. BMC Genomics, vol 13, pp. 623.
    [Online] DOI: 10.1186/1471-2164-13-623
  • Lim, PH., Pisat, NP., Gadhia, N., Pandey, A., Donovan, FX., Stein, L., Salt, DE., Eide, DJ. & MacDiarmid, CW. (2011). 'Regulation of Alr1 Mg Transporter Activity by Intracellular Magnesium'. PLoS ONE, vol 6, no. 6, pp. -.
    [Online] DOI: 10.1371/journal.pone.0020896
  • Na, G. & Salt, DE. (2011). 'The role of sulfur assimilation and sulfur-containing compounds in trace element homeostasis in plants'. Environmental and Experimental Botany, vol 72, no. 1, pp. 18-25.
    [Online] DOI: 10.1016/j.envexpbot.2010.04.004
  • Chao, D-Y, Gable, K., Chen, M., Baxter, I., Dietrich, CR., Cahoon, EB., Guerinot, ML., Lahner, B., Lue, S., Markham, JE., Morrissey, J., Han, G., Gupta, SD., Harmon, JM., Jaworski, JG., Dunn, TM. & Salt, DE. (2011). 'Sphingolipids in the Root Play an Important Role in Regulating the Leaf Ionome in Arabidopsis thaliana'. The Plant Cell, vol 23, no. 3, pp. 1061-1081.
    [Online] DOI: 10.1105/tpc.110.079095
  • Gustin, JL., Zanis, MJ. & Salt, DE. (2011). 'Structure and evolution of the plant cation diffusion facilitator family of ion transporters'. BMC Evolutionary Biology, vol 11, pp. 76.
    [Online] DOI: 10.1186/1471-2148-11-76
  • Becker, A., Chao, D-Y, Zhang, X., Salt, DE. & Baxter, I. (2011). 'Bulk Segregant Analysis Using Single Nucleotide Polymorphism Microarrays'. PLoS ONE, vol 6, no. 1.
    [Online] DOI: 10.1371/journal.pone.0015993
  • Fleet, JC., Replogle, R. & Salt, DE. (2011). 'Systems Genetics of Mineral Metabolism'. Journal of Nutrition, vol 141, no. 3, pp. 520-525.
    [Online] DOI: 10.3945/jn.110.128736
  • Borghi, M., Rus, A. & Salt, DE. (2011). 'Loss-of-Function of Constitutive Expresser of Pathogenesis Related Genes5 Affects Potassium Homeostasis in Arabidopsis thaliana'. PLoS ONE, vol 6, no. 10, e26360.
    [Online] DOI: 10.1371/journal.pone.0026360
  • Na, G. & Salt, DE. (2011). 'Differential Regulation of Serine Acetyltransferase Is Involved in Nickel Hyperaccumulation in Thlaspi goesingense'. Journal of Biological Chemistry, vol 286, no. 47, pp. 40423-40432.
    [Online] DOI: 10.1074/jbc.M111.247411
  • Yu, D., Danku, J., Baxter, I., Kim, S., Vatamaniuk, OK., Salt, DE. & Vitek, O. (2011). 'Noise reduction in genome-wide perturbation screens using linear mixed-effect models'. Bioinformatics, vol 27, no. 16, pp. 2173-2180.
    [Online] DOI: 10.1093/bioinformatics/btr359
  • Tian, H., Baxter, IR., Lahner, B., Reinders, A., Salt, DE. & Ward, JM. (2010). 'Arabidopsis NPCC6/NaKR1 Is a Phloem Mobile Metal Binding Protein Necessary for Phloem Function and Root Meristem Maintenance'. The Plant Cell, vol 22, no. 12, pp. 3963-3979.
    [Online] DOI: 10.1105/tpc.110.080010
  • Robinson, GE., Banks, JA., Padilla, DK., Burggren, WW., Cohen, CS., Delwiche, CF., Funk, V., Hoekstra, HE., Jarvis, ED., Johnson, L., Martindale, MQ., del Rio, CM., Medina, M., Salt, DE., Sinha, S., Specht, C., Strange, K., Strassmann, JE., Swalla, BJ. & Tomanek, L. (2010). 'Empowering 21st Century Biology'. Bioscience, vol 60, no. 11, pp. 923-930.
    [Online] DOI: 10.1525/bio.2010.60.11.8
  • Mason, MG., Jha, D., Salt, DE., Tester, M., Hill, K., Kieber, JJ. & Schaller, GE. (2010). 'Type-B response regulators ARR1 and ARR12 regulate expression of AtHKT1;1 and accumulation of sodium in Arabidopsis shoots'. The Plant Journal, vol 64, no. 5, pp. 753-763.
    [Online] DOI: 10.1111/j.1365-313X.2010.04366.x
  • Baxter, I., Brazelton, JN., Yu, D., Huang, YS., Lahner, B., Yakubova, E., Li, Y., Bergelson, J., Borevitz, JO., Nordborg, M., Vitek, O. & Salt, DE. (2010). 'A Coastal Cline in Sodium Accumulation in Arabidopsis thaliana Is Driven by Natural Variation of the Sodium Transporter AtHKT1;1'. PLoS Genetics, vol 6, no. 11.
    [Online] DOI: 10.1371/journal.pgen.1001193
  • Prinzenberg, AE., Barbier, H., Salt, DE., Stich, B. & Reymond, M. (2010). 'Relationships between Growth, Growth Response to Nutrient Supply, and Ion Content Using a Recombinant Inbred Line Population in Arabidopsis'. Plant Physiology, vol 154, no. 3, pp. 1361-1371.
    [Online] DOI: 10.1104/pp.110.161398
  • Mills, RF., Valdes, B., Duke, M., Peaston, KA., Lahner, B., Salt, DE. & Williams, LE. (2010). 'Functional Significance of AtHMA4 C-Terminal Domain In Planta'. PLoS ONE, vol 5, no. 10, e13388.
    [Online] DOI: 10.1371/journal.pone.0013388
  • Long, TA., Tsukagoshi, H., Busch, W., Lahner, B., Salt, DE. & Benfey, PN. (2010). 'The bHLH Transcription Factor POPEYE Regulates Response to Iron Deficiency in Arabidopsis Roots'. The Plant Cell, vol 22, no. 7, pp. 2219-2236.
    [Online] DOI: 10.1105/tpc.110.074096
  • Chu, H-H, Chiecko, J., Punshon, T., Lanzirotti, A., Lahner, B., Salt, DE. & Walker, EL. (2010). 'Successful Reproduction Requires the Function of Arabidopsis YELLOW STRIPE-LIKE1 and YELLOW STRIPE-LIKE3 Metal-Nicotianamine Transporters in Both Vegetative and Reproductive Structures'. Plant Physiology, vol 154, no. 1, pp. 197-210.
    [Online] DOI: 10.1104/pp.110.159103
  • Indriolo, E., Na, G., Ellis, D., Salt, DE. & Banks, JA. (2010). 'A Vacuolar Arsenite Transporter Necessary for Arsenic Tolerance in the Arsenic Hyperaccumulating Fern Pteris vittata Is Missing in Flowering Plants'. The Plant Cell, vol 22, no. 6, pp. 2045-2057.
    [Online] DOI: 10.1105/tpc.109.069773
  • Buescher, E., Achberger, T., Amusan, I., Giannini, A., Ochsenfeld, C., Rus, A., Lahner, B., Hoekenga, O., Yakubova, E., Harper, JF., Guerinot, ML., Zhang, M., Salt, DE. & Baxter, IR. (2010). 'Natural Genetic Variation in Selected Populations of Arabidopsis thaliana Is Associated with Ionomic Differences'. PLoS ONE, vol 5, no. 6.
    [Online] DOI: 10.1371/journal.pone.0011081
  • Atwell, S., Huang, YS., Vilhjalmsson, BJ., Willems, G., Horton, M., Li, Y., Meng, D., Platt, A., Tarone, AM., Hu, TT., Jiang, R., Muliyati, NW., Zhang, X., Amer, MA., Baxter, I., Brachi, B., Chory, J., Dean, C., Debieu, M., de Meaux, J., Ecker, JR., Faure, N., Kniskern, JM., Jones, JDG., Michael, T., Nemri, A., Roux, F., Salt, DE., Tang, C., Todesco, M., Traw, MB., Weigel, D., Marjoram, P., Borevitz, JO., Bergelson, J. & Nordborg, M. (2010). 'Genome-wide association study of 107 phenotypes in Arabidopsis thaliana inbred lines'. Nature, vol 465, no. 7298, pp. 627-631.
    [Online] DOI: 10.1038/nature08800
  • Yang, J., Worley, E., Wang, M., Lahner, B., Salt, DE., Saha, M. & Udvardi, M. (2009). 'Natural Variation for Nutrient Use and Remobilization Efficiencies in Switchgrass'. BioEnergy Research, vol 2, no. 4, pp. 257-266.
    [Online] DOI: 10.1007/s12155-009-9055-9
  • Morrissey, J., Baxter, IR., Lee, J., Li, L., Lahner, B., Grotz, N., Kaplan, J., Salt, DE. & Guerinot, ML. (2009). 'The Ferroportin Metal Efflux Proteins Function in Iron and Cobalt Homeostasis in Arabidopsis'. The Plant Cell, vol 21, no. 10, pp. 3326-3338.
    [Online] DOI: 10.1105/tpc.109.069401
  • Guimaraes, MDA., Gustin, JL. & Salt, DE. (2009). 'Reciprocal grafting separates the roles of the root and shoot in zinc hyperaccumulation in Thlaspi caerulescens'. New Phytologist, vol 184, no. 2, pp. 323-329.
    [Online] DOI: 10.1111/j.1469-8137.2009.02969.x
  • Lowry, DB., Hall, MC., Salt, DE. & Willis, JH. (2009). 'Genetic and physiological basis of adaptive salt tolerance divergence between coastal and inland Mimulus guttatus'. New Phytologist, vol 183, no. 3, pp. 776-788.
    [Online] DOI: 10.1111/j.1469-8137.2009.02901.x
  • Sors, TG., Martin, CP. & Salt, DE. (2009). 'Characterization of selenocysteine methyltransferases from Astragalus species with contrasting selenium accumulation capacity'. The Plant Journal, vol 59, no. 1, pp. 110-122.
    [Online] DOI: 10.1111/j.1365-313X.2009.03855.x
  • Baxter, I., Hosmani, PS., Rus, A., Lahner, B., Borevitz, JO., Muthukumar, B., Mickelbart, MV., Schreiber, L., Franke, RB. & Salt, DE. (2009). 'Root Suberin Forms an Extracellular Barrier That Affects Water Relations and Mineral Nutrition in Arabidopsis'. PLoS Genetics, vol 5, no. 5, e1000492.
    [Online] DOI: 10.1371/journal.pgen.1000492
  • Gustin, JL., Loureiro, ME., Kim, D., Na, G., Tikhonova, M. & Salt, DE. (2009). 'MTP1-dependent Zn sequestration into shoot vacuoles suggests dual roles in Zn tolerance and accumulation in Zn-hyperaccumulating plants'. The Plant Journal, vol 57, no. 6, pp. 1116-1127.
    [Online] DOI: 10.1111/j.1365-313X.2008.03754.x
  • Danku, JMC., Gumaelius, L., Baxter, I. & Salt, DE. (2009). 'A high-throughput method for Saccharomyces cerevisiae (yeast) ionomics'. Journal of Analytical Atomic Spectrometry, vol 24, no. 1, pp. 103-107.
    [Online] DOI: 10.1039/b803529f
  • Baxter, IR., Vitek, O., Lahner, B., Muthukumar, B., Borghi, M., Morrissey, J., Guerinot, ML. & Salt, DE. (2008). 'The leaf ionome as a multivariable system to detect a plant's physiological status'. PNAS, vol 105, no. 33, pp. 12081-12086.
    [Online] DOI: 10.1073/pnas.0804175105
  • Ward, JT., Lahner, B., Yakubova, E., Salt, DE. & Raghothama, KG. (2008). 'The effect of iron on the primary root elongation of Arabidopsis during phosphate deficiency'. Plant Physiology, vol 147, no. 3, pp. 1181-1191.
    [Online] DOI: 10.1104/pp.108.118562
  • Kerkeb, L., Mukherjee, I., Chatterjee, I., Lahner, B., Salt, DE. & Connolly, EL. (2008). 'Iron-induced turnover of the Arabidopsis IRON- REGULATED TRANSPORTER1 metal transporter requires lysine residues'. Plant Physiology, vol 146, no. 4, pp. 1964-1973.
    [Online] DOI: 10.1104/pp.107.113282
  • Baxter, I., Muthukumar, B., Park, HC., Buchner, P., Lahner, B., Danku, J., Zhao, K., Lee, J., Hawkesford, MJ., Guerinot, ML. & Salt, DE. (2008). 'Variation in molybdenum content across broadly distributed populations of Arabidopsis thaliana is controlled by a mitochondrial molybdenum transporter (MOT1)'. PLoS Genetics, vol 4, no. 2, pp. -.
    [Online] DOI: 10.1371/journal.pgen.1000004
  • Kambe, T., Geiser, J., Lahner, B., Salt, DE. & Andrews, GK. (2008). 'Slc39a1 to 3 (subfamily II) Zip genes in mice have unique cell-specific functions during adaptation to zinc deficiency'. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, vol 294, no. 5, pp. R1474-R1481.
    [Online] DOI: 10.1152/ajpregu.00130.2008
  • Zhang, M., Ouyang, Q., Stephenson, A., Kane, MD., Salt, DE., Prabhakar, S., Burgner, J., Buck, C. & Zhang, X. (2008). 'Interactive analysis of systems biology molecular expression data'. BMC Systems Biology, vol 2, no. 23, pp. -.
    [Online] DOI: 10.1186/1752-0509-2-23
  • Freeman, JL. & Salt, DE. (2007). 'The metal tolerance profile of Thlaspi goesingense is mimicked in Arabidopsis thaliana heterologously expressing serine acetyl-transferase'. Bmc plant biology, vol 7, 63, pp. -.
    [Online] DOI: 10.1186/1471-2229-7-63
  • Muthukumar, B., Yakubov, B. & Salt, DE. (2007). 'Transcriptional activation and localization of expression of Brassica juncea putative metal transport protein BjMTPI'. Bmc plant biology, vol 7, 32, pp. -.
    [Online] DOI: 10.1186/1471-2229-7-32
  • Callahan, DL., Kolev, SD., O'Hair, RAJ., Salt, DE. & Baker, AJM. (2007). 'Relationships of nicotianamine and other amino acids with nickel, zinc and iron in Thlaspi hyperaccumulators'. New Phytologist, vol 176, no. 4, pp. 836-848.
    [Online] DOI: 10.1111/j.1469-8137.2007.02216.x
  • Peters, JL., Dufner-Beattie, J., Xu, W., Geiser, J., Lahner, B., Salt, DE. & Andrews, GK. (2007). 'Targeting of the mouse Slc39a2 (Zip2) gene reveals highly cell-specific patterns of expression, and unique functions in zinc, iron, and calcium homeostasis'. Genesis, vol 45, no. 6, pp. 339-352.
    [Online] DOI: 10.1002/dvg.20297
  • Baxter, I., Ouzzani, M., Orcun, S., Kennedy, B., Jandhyala, SS. & Salt, DE. (2007). 'Purdue Ionomics Information Management System. An integrated functional genomics platform'. Plant Physiology, vol 143, no. 2, pp. 600-611.
    [Online] DOI: 10.1104/pp.106.092528
  • Lee, J., Nam, J., Park, HC., Na, G., Miura, K., Jin, GBJ., Yoo, CY., Baek, D., Kim, DH., Jeong, JC., Kim, D., Lee, SY., Salt, DE., Mengiste, T., Gong, Q., Ma, S., Bohnert, HJ., Kwak, S-S, Bressan, RA., Hasegawa, PM. & Yun, D-J (2007). 'Salicylic acid-mediated innate immunity in Arabidopsis is regulated by SIZ1 SUMO E3 ligase'. The Plant Journal, vol 49, no. 1, pp. 79-90.
    [Online] DOI: 10.1111/j.1365-313X.2006.02947.x
  • Simm, C., Lahner, B., Salt, D., LeFurgey, A., Ingram, P., Yandell, B. & Eide, DJ. (2007). 'Saccharomyces cerevisiae vacuole in zinc storage and intracellular zinc distribution'. Eukaryotic Cell, vol 6, no. 7, pp. 1166-1177.
    [Online] DOI: 10.1128/EC.00077-07
  • Rus, A., Baxter, I., Muthukumar, B., Gustin, J., Lahner, B., Yakubova, E. & Salt, DE. (2006). 'Natural variants of AtHKT1 enhance Na+ accumulation in two wild Populations of Arabidopsis'. PLoS Genetics, vol 2, no. 12, e210, pp. 1964-1973.
    [Online] DOI: 10.1371/journal.pgen.0020210
  • Rampey, RA., Woodward, AW., Hobbs, BN., Tierney, MP., Lahner, B., Salt, DE. & Bartel, B. (2006). 'An arabidopsis basic helix-loop-helix leucine zipper protein modulates metal homeostasis and auxin conjugate responsiveness'. Genetics, vol 174, no. 4, pp. 1841-1857.
    [Online] DOI: 10.1534/genetics.106.061044
  • Yoo, CY., Miura, K., Jin, JB., Lee, J., Park, HC., Salt, DE., Yun, D-J, Bressan, RA. & Hasegawa, PM. (2006). 'SIZ1 small ubiquitin-like modifier E3 ligase facilitates basal thermotolerance in Arabidopsis independent of salicylic acid'. Plant Physiology, vol 142, no. 4, pp. 1548-1558.
    [Online] DOI: 10.1104/pp.106.088831
  • Peer, WA., Mahmoudian, M., Freeman, JL., Lahner, B., Richards, EL., Reeves, RD., Murphy, AS. & Salt, DE. (2006). 'Assessment of plants from the Brassicaceae family as genetic models for the study of nickel and zinc hyperaccumulation'. New Phytologist, vol 172, no. 2, pp. 248-260.
    [Online] DOI: 10.1111/j.1469-8137.2006.01820.x
  • Waters, BM., Chu, H-H, DiDonato, RJ., Roberts, LA., Eisley, RB., Lahner, B., Salt, DE. & Walker, EL. (2006). 'Mutations in Arabidopsis Yellow Stripe-Like1 and Yellow Stripe-Like3 reveal their roles in metal ion homeostasis and loading of metal ions in seeds'. Plant Physiology, vol 141, no. 4, pp. 1446-1458.
    [Online] DOI: 10.1104/pp.106.082586
  • Ellis, DR., Gumaelius, L., Indriolo, E., Pickering, IJ., Banks, JA. & Salt, DE. (2006). 'A novel arsenate reductase from the arsenic hyperaccumulating fern Pteris vittata'. Plant Physiology, vol 141, no. 4, pp. 1544-1554.
    [Online] DOI: 10.1104/pp.106.084079
  • Pickering, IJ., Gumaelius, L., Harris, HH., Prince, RC., Hirsch, G., Banks, JA., Salt, DE. & George, GN. (2006). 'Localizing the biochemical transformations of arsenate in a hyperaccumulating fern'. Environmental Science & Technology, vol 40, no. 16, pp. 5010-5014.
    [Online] DOI: 10.1021/es052559a
  • Freeman, JL., Persans, MW., Nieman, K. & Salt, DE. (2005). 'Nickel and cobalt resistance engineered in Escherichia coli by overexpression of serine acetyltransferase from the nickel hyperaccumulator plant Thlaspi goesingense'. Applied and Environmental Microbiology, vol 71, no. 12, pp. 8627-8633.
    [Online] DOI: 10.1128/AEM.71.12.8627-8633.2005
  • Cheng, NH., Pittman, JK., Shigaki, T., Lachmansingh, J., LeClere, S., Lahner, B., Salt, DE. & Hirschi, KD. (2005). 'Functional association of Arabidopsis CAX1 and CAX3 is required for normal growth and ion homeostasis'. Plant Physiology, vol 138, no. 4, pp. 2048-2060.
    [Online] DOI: 10.1104/pp.105.061218
  • Sors, TG., Ellis, DR., Na, GN., Lahner, B., Lee, S., Leustek, T., Pickering, IJ. & Salt, DE. (2005). 'Analysis of sulfur and selenium assimilation in Astragalus plants with varying capacities to accumulate selenium'. The Plant Journal, vol 42, no. 6, pp. 785-797.
    [Online] DOI: 10.1111/j.1365-313X.2005.02413.x
  • Freeman, JL., Garcia, D., Kim, DG., Hopf, A. & Salt, DE. (2005). 'Constitutively elevated salicylic acid signals glutathione-mediated nickel tolerance in Thlaspi nickel hyperaccumulators'. Plant Physiology, vol 137, no. 3, pp. 1082-1091.
    [Online] DOI: 10.1104/pp.104.055293
  • Gumaelius, L., Lahner, B., Salt, DE. & Banks, JA. (2004). 'Arsenic hyperaccumulation in gametophytes of Pteris vittata: a new model system for analysis of arsenic hyperaccumulation'. Plant Physiology, vol 136, no. 2, pp. 3198-3208.
    [Online] DOI: 10.1104/pp.104.044073
  • Salt, DE. (2004). 'Update on plant ionomics'. Plant Physiology, vol 136, no. 1, pp. 2451-2456.
    [Online] DOI: 10.1104/pp.104.047753
  • Freeman, JL., Persans, MW., Nieman, K., Albrecht, C., Peer, WA., Pickering, IJ. & Salt, DE. (2004). 'Increased glutathione biosynthesis plays a role in nickel tolerance in Thlaspi nickel hyperaccumulators'. The Plant Cell, vol 16, no. 8, pp. 2176-2191.
    [Online] DOI: 10.1105/tpc.104.023036
  • Kim, D., Gustin, JL., Lahner, B., Persans, MW., Baek, D., Yun, D-J & Salt, DE. (2004). 'The plant CDF family member TgMTP1 from the Ni/Zn hyperaccumulator Thlaspi goesingense acts to enhance efflux of Zn at the plasma membrane when expressed in Saccharomyces cerevisiae'. The Plant Journal, vol 39, no. 2, pp. 237-251.
    [Online] DOI: 10.1111/j.1365-313X.2004.02126.x
  • Ticconi, CA., Delatorre, CA., Lahner, B., Salt, DE. & Abel, S. (2004). 'Arabidopsis pdr2 reveals a phosphate-sensitive checkpoint in root development'. The Plant Journal, vol 37, no. 6, pp. 801-814.
    [Online] DOI: 10.1111/j.1365-313X.2004.02005.x
  • Whiting, SN., Reeves, RD., Richards, D., Johnson, MS., Cooke, JA., Malaisse, F., Paton, DA., Smith, JA.C, Angle, JS., Chaney, RL., Ginocchio, R., Jaffre, T., Johns, R., McIntyre, T., Purvis, OW., Salt, DE., Schat, H., Zhao, FJ. & Baker, AJM. (2004). 'Research priorities for conservation of metallophyte biodiversity and their potential for restoration and site remediation'. Restoration ecology, vol 12, no. 1, pp. 106-116.
    [Online] DOI: 10.1111/j.1061-2971.2004.00367.x
  • Pickering, IJ., Prince, RC., Salt, DE. & George, GN. (2003). 'Metals and metalloids in plants: What can X-rays tell us?'. Abstracts of Papers of the American Chemical Society, vol 225, pp. U837.
  • Lahner, B., Gong, JM., Mahmoudian, M., Smith, EL., Abid, KB., Rogers, EE., Guerinot, ML., Harper, JF., Ward, JM., McIntyre, L., Schroeder, JI. & Salt, DE. (2003). 'Genomic scale profiling of nutrient and trace elements in Arabidopsis thaliana'. Nature Biotechnology, vol 21, no. 10, pp. 1215-1221.
    [Online] DOI: 10.1038/nbt865
  • Pickering, IJ., Wright, C., Bubner, B., Ellis, D., Persans, MW., Yu, EY., George, GN., Prince, RC. & Salt, DE. (2003). 'Chemical form and distribution of selenium and sulfur in the selenium hyperaccumulator Astragalus bisulcatus'. Plant Physiology, vol 131, no. 3, pp. 1460-1467.
    [Online] DOI: 10.1104/pp.014787
  • Peer, WA., Mamoudian, M., Lahner, B., Reeves, RD., Murphy, AS. & Salt, DE. (2003). 'Identifying model metal hyperaccumulating plants: germplasm analysis of 20 Brassicaceae accessions from a wide geographical area'. New Phytologist, vol 159, no. 2, pp. 421-430.
    [Online] DOI: 10.1046/j.1469-8137.2003.00822.x
  • Pickering, IJ., Hirsch, G., Prince, RC., Sneeden, EY., Salt, DE. & George, GN. (2003). 'Imaging of selenium in plants using tapered metal monocapillary optics'. Journal of synchrotron radiation, vol 10, pp. 289-290.
    [Online] DOI: 10.1107/S0909049503003273
  • Salt, DE., Prince, RC. & Pickering, IJ. (2002). 'Chemical speciation of accumulated metals in plants: evidence from X-ray absorption spectroscopy'. Microchemical Journal, vol 71, no. 2-3, pp. 255-259.
  • Prince, RC., Gailer, J., Salt, DE., George, GN. & Pickering, IJ. (2002). 'Selenium, arsenic and mercury in plants and animals: Can a little poison do you good?'. Abstracts of Papers of the American Chemical Society, vol 223, pp. A10-A10.
  • Dhankher, OP., Li, YJ., Rosen, BP., Shi, J., Salt, DE., Senecoff, JF., Sashti, NA., Meagher, RB. & Salt, DE. (2002). 'Engineering tolerance and hyperaccumulation of arsenic in plants by combining arsenate reductase and gamma-glutamylcysteine synthetase expression'. Nature Biotechnology, vol 20, no. 11, pp. 1140-1145.
    [Online] DOI: 10.1038/nbt747
  • Persans, MW., Nieman, K. & Salt, DE. (2001). 'Functional activity and role of cation-efflux family members in Ni hyperaccumulation in Thlaspi goesingense'. PNAS, vol 98, no. 17, pp. 9995-10000.
  • Pickering, IJ., Prince, RC., Salt, DE. & George, GN. (2000). 'Quantitative, chemically specific imaging of selenium transformation in plants'. PNAS, vol 97, no. 20, pp. 10717-10722.
  • Pickering, IJ., Salt, DE., Prince, RC., Hirsch, G. & George, GN. (2000). 'Chemical and spatial speciation of selenium in environmental samples'. Abstracts of Papers of the American Chemical Society, vol 219, pp. U748-U748.
  • Pickering, IJ., Prince, RC., George, MJ., Smith, RD., George, GN. & Salt, DE. (2000). 'Reduction and coordination of arsenic in Indian mustard'. Plant Physiology, vol 122, no. 4, pp. 1171-1177.
  • Kramer, U., Pickering, IJ., Prince, RC., Raskin, I. & Salt, DE. (2000). 'Subcellular localization and speciation of nickel in hyperaccumulator and non-accumulator Thlaspi species'. Plant Physiology, vol 122, no. 4, pp. 1343-1353.
  • Persans, MW., Yan, XG., Patnoe, JMML., Kramer, U. & Salt, DE. (1999). 'Molecular dissection of the role of histidine in nickel hyperaccumulation in Thlaspi goesingense (Halacsy)'. Plant Physiology, vol 121, no. 4, pp. 1117-1126.
  • Schulman, RN., Salt, DE. & Raskin, I. (1999). 'Isolation and partial characterization of a lead-accumulating Brassica juncea mutant'. Theoretical and Applied Genetics, vol 99, no. 3-4, pp. 398-404.
  • Salt, DE., Prince, RC., Baker, AJM., Raskin, I. & Pickering, IJ. (1999). 'Zinc ligands in the metal hyperaccumulator Thlaspi caerulescens as determined using X-ray absorption spectroscopy'. Environmental Science & Technology, vol 33, no. 5, pp. 713-717.
  • Pickering, IJ., Prince, RC., George, GN., Rauser, WE., Wickramasinghe, WA., Watson, AA., Dameron, CT., Dance, IG., Fairlie, DP. & Salt, DE. (1999). 'X-ray absorption spectroscopy of cadmium phytochelatin and model systems'. Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, vol 1429, no. 2, pp. 351-364.
  • Vassil, AD., Kapulnik, Y., Raskin, I. & Salt, DE. (1998). 'The role of EDTA in lead transport and accumulation by Indian mustard'. Plant Physiology, vol 117, no. 2, pp. 447-453.
  • Kramer, U., Smith, RD., Wenzel, WW., Raskin, I. & Salt, DE. (1997). 'The role of metal transport and tolerance in nickel hyperaccumulation by Thlaspi goesingense Halacsy'. Plant Physiology, vol 115, no. 4, pp. 1641-1650.
  • Salt, DE., Pickering, IJ., Prince, RC., Gleba, D., Dushenkov, S., Smith, RD. & Raskin, I. (1997). 'Metal accumulation by aquacultured seedlings of Indian mustard'. Environmental Science & Technology, vol 31, no. 6, pp. 1636-1644.
  • Blaylock, MJ., Salt, DE., Dushenkov, S., Zakharova, O., Gussman, C., Kapulnik, Y., Ensley, BD. & Raskin, I. (1997). 'Enhanced accumulation of Pb in Indian mustard by soil-applied chelating agents'. Environmental Science & Technology, vol 31, no. 3, pp. 860-865.
  • Salt, DE., Bentham, AC., Hay, S., Idris, A., Gregory, J., Hoare, M. & Dunnill, P. (1996). 'The mechanism of flocculation of a Saccharomyces cerevisiae cell homogenate using polyethyleneimine'. Bioprocess engineering, vol 15, no. 2, pp. 71-76.
  • SALT, DE., PRINCE., RC., PICKERING., IJ. & RASKIN, I. (1995). 'MECHANISMS OF CADMIUM MOBILITY AND ACCUMULATION IN INDIAN MUSTARD'. Plant Physiology, vol 109, no. 4, pp. 1427-1433.
  • SALT, DE. & RAUSER, WE. (1995). 'MGATP-DEPENDENT TRANSPORT OF PHYTOCHELATINS ACROSS THE TONOPLAST OF OAT ROOTS'. Plant Physiology, vol 107, no. 4, pp. 1293-1301.
  • SALT, DE., HAY., S., THOMAS., ORT., HOARE., M. & DUNNILL, P. (1995). 'SELECTIVE FLOCCULATION OF CELLULAR CONTAMINANTS FROM SOLUBLE-PROTEINS USING POLYETHYLENEIMINE - A STUDY OF SEVERAL ORGANISMS AND POLYMER MOLECULAR-WEIGHTS'. Enzyme and microbial technology, vol 17, no. 2, pp. 107-113.
  • SALT, DE. & WAGNER, GJ. (1993). 'CADMIUM TRANSPORT ACROSS TONOPLAST OF VESICLES FROM OAT ROOTS - EVIDENCE FOR A CD2+/H+ ANTIPORT ACTIVITY'. Journal of Biological Chemistry, vol 268, no. 17, pp. 12297-12302.
  • SALT, DE., THURMAN., DA., TOMSETT., AB. & SEWELL, AK. (1989). 'Copper Phytochelatins of Mimulus-Guttatus'. Proceedings of the Royal Society of London. B, Biological Sciences, vol 236, no. 1282, pp. 79-89.

Letters

  • Broadley, MR., Hammond, JP., White, PJ. & Salt, DE. (2010). 'An efficient procedure for normalizing ionomics data for Arabidopsis thaliana'. New Phytologist, vol 186, no. 2, pp. 270-274.
    [Online] DOI: 10.1111/j.1469-8137.2009.03145.x
  • Baxter, IR., Vitek, O., Guerinot, ML. & Salt, DE. (2009). 'Reply to Evens and Niedz: Multivariate ionomics models are robustly validated'. PNAS, vol 106, no. 2, pp. E6.
    [Online] DOI: 10.1073/pnas.0811786106

Comments and Debates

  • Salt, DE. (1998). 'Arboreal alchemy'. Nature Biotechnology, vol 16, no. 10, pp. 905-905.

Scientific Reviews

  • Salt, DE., Baxter, I. & Lahner, B. (2008). 'Ionomics and the study of the plant ionome'. Annual Review of Plant Biology, vol 59, pp. 709-733.
    [Online] DOI: 10.1146/annurev.arplant.59.032607.092942
  • Sors, TG., Ellis, DR. & Salt, DE. (2005). 'Selenium uptake, translocation, assimilation and metabolic fate in plants'. Photosynthesis research, vol 86, no. 3, pp. 373-389.
    [Online] DOI: 10.1007/s11120-005-5222-9
  • Ellis, DR. & Salt, DE. (2003). 'Plants, selenium and human health'. Current Opinion in Plant Biology, vol 6, no. 3, pp. 273-279.
    [Online] DOI: 10.1016/S1369-5266(03)00030-X
  • Maser, P., Thomine, S., Schroeder, JI., Ward, JM., Hirschi, K., Sze, H., Talke, IN., Amtmann, A., Maathuis, FJM., Sanders, D., Harper, JF., Tchieu, J., Gribskov, M., Persans, MW., Salt, DE., Kim, SA. & Guerinot, ML. (2001). 'Phylogenetic relationships within cation transporter families of Arabidopsis'. Plant Physiology, vol 126, no. 4, pp. 1646-1667.
  • Salt, DE., Smith, RD. & Raskin, I. (1998). 'Phytoremediation'. Annual review of plant physiology and plant molecular biology, vol 49, pp. 643-668.
  • Raskin, I., Smith, RD. & Salt, DE. (1997). 'Phytoremediation of metals: Using plants to remove pollutants from the environment'. Current Opinion in Biotechnology, vol 8, no. 2, pp. 221-226.
  • SALT, DE., BLAYLOCK., M., KUMAR., NPBA., DUSHENKOV., V., ENSLEY, BD., CHET., I. & RASKIN, I. (1995). 'PHYTOREMEDIATION - A NOVEL STRATEGY FOR THE REMOVAL OF TOXIC METALS FROM THE ENVIRONMENT USING PLANTS'. Bio-Technology, vol 13, no. 5, pp. 468-474.

Editorials

  • Williams, L. & Salt, DE. (2009). 'The plant ionome coming into focus'. Current Opinion in Plant Biology, vol 12, no. 3, pp. 247-249.
    [Online] DOI: 10.1016/j.pbi.2009.05.009
  • Salt, DE. & Norton, GJ. (2008). 'Arsenic-eaters: by accident or by design'. New Phytologist, vol 180, no. 1, pp. 8-11.
    [Online] DOI: 10.1111/j.1469-8137.2008.02609.x
  • Guerinot, ML. & Salt, DE. (2001). 'Fortified foods and phytoremediation. Two sides of the same coin'. Plant Physiology, vol 125, no. 1, pp. 164-167.

Chapters in Books, Reports and Conference Proceedings

Conference Proceedings

  • Eltabkh, MY., Ouzzani, M., Aref, WG., Elmagarmid, AK., Laura-Silva, Y., Arshad, MU., Salt, D. & Baxter, I. (2008). 'Managing biological data using bdbms'. in 2008 IEEE 24th International Conference on Data Engineering, Vols 1-3. IEEE Press, New York, pp. 1600-1603, 24th IEEE International Conference on Data Engineering, Cancun, 7-12 April.
  • Salt, DE., Kato, N., Kramer, U., Smith, RD. & Raskin, I. (2000). 'The role of root exudates in nickel hyperaccumulation and tolerance in accumulator and nonaccumulator species of Thlaspi'. in N Terry & G Banuelos (eds), PHYTOREMEDIATION OF CONTAMINATED SOIL AND WATER. LEWIS PUBLISHERS INC, BOCA RATON, pp. 189-200.
  • Ensley, BD., Raskin, I. & Salt, DE. (1997). 'Phytoremediation application for removing heavy metal contamination from soil and water'. in GS Sayler, J Sanseverino & KL Davis (eds), BIOTECHNOLOGY IN THE SUSTAINABLE ENVIRONMENT. PLENUM PRESS DIV PLENUM PUBLISHING CORP, NEW YORK, pp. 59-64, Conference on Biotechnology in the Sustainable Environment, KNOXVILLE, 14-17 April.

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