Prof Michael Frenneaux
MB BS, PhD, FRCP
Professor Frenneaux is the newly appointed Regius Chair of Medicine at Aberdeen University and is an honorary Consultant Cardiologist. Prior to this appointment he was the BHF Chair in Cardiology and Head of the Department for Cardiovascular Medicien at Birmingham University.
He qualified in London and has previously held Chairs in Brisbane and Cardiff. Professor Frenneaux is a Clinical Cardiologist whose major interests include heart failure and cardiomyopathies. His research is wide ranging but is best described as integrated physiology. He is currently working on a new treatment for heart failure based around the drug perhexiline. One of his research interests has been the mechanisms responsible for increased cardiovascular risk in individuals with a past history of depression and has focussed on the potential effects of increased Cortisol on the endothelium.
Williams LK, Ellery S, Patel K, Leyva F, Bleasdale RA, Phan TT, Stegemann B, Paul V, Steendijk P, Frenneaux M. Short-term hemodynamic effects of cardiac resynchronization therapy in patients with heart failure, a narrow QRS duration, and no dyssynchrony. Circulation. 2009 Oct 27;120(17):1687-94.
Phan TT, Abozguia K, Nallur Shivu G, Mahadevan G, Ahmed I, Williams L, Dwivedi G, Patel K, Steendijk P, Ashrafian H, Henning A, Frenneaux M. Heart failure with preserved ejection fraction is characterized by dynamic impairment of active relaxation and contraction of the left ventricle on exercise and associated with myocardial energy deficiency. J Am Coll Cardiol. 2009 Jul 28;54(5):402-9.
Foley PW, Chalil S, Khadjooi K, Jordan P, Smith RE, Frenneaux MP, Leyva F. Effects of cardiac resynchronization therapy in patients unselected for mechanical dyssynchrony. Int J Cardiol. 2009 Feb 24.
Maher AR, Milsom AB, Gunaruwan P, Abozguia K, Ahmed I, Weaver RA, Thomas P, Ashrafian H, Born GV, James PE, Frenneaux MP. Hypoxic modulation of exogenous nitrite-induced vasodilation in humans. Circulation. 2008 Feb 5;117(5):670-7.Abozguia K, Clarke K, Lee L, Frenneaux M. Modification of myocardial substrate use as a therapy for heart failure. Nat Clin Pract Cardiovasc Med. 2006 Sep;3(9):490-8. Review.